6 recruiting, 4 not yet recruiting, 2 completed, 1 enrolling by invitation. 7 Not applicable, 4 Phase 4, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Completed 2, Not yet recruiting 2, Recruiting 2, Enrolling by invitation 1 |
| Phase 4 | 4 | Not yet recruiting 2, Recruiting 2 |
| Phase 2 | 2 | Recruiting 2 |
Follow GLP - 1: new trials by email Literature Review of GLP - 1 trials Research Report on GLP - 1
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Scalable Behavioral Program for Weight Loss Maintenance After GLP-1 and Anti-Obesity Medication Discontinuation Weight Loss Maintenance Program (Foundational), Mom's Meals, YMCA Membership - Weight Loss, GLP - 1 | Not applicable | Not yet recruiting | University of Alabama at Birmingham | 64 | 2026-11-01 | 2026-06-26 |
| GLP-1s in Hip and Knee Arthroplasty GLP-1 Receptor Agonists + Behavioral modification, Behavioral + placebo - Arthritis, Obesity & Overweight | Phase 4 | Not yet recruiting | Nova Scotia Health Authority | 100 | 2026-10-01 | 2026-08-10 |
| A Study on Ubiquinol on Fatigue and Muscle Strength in Healthy Adults Taking GLP-1 Agonists Ubiquinol 100 MG Oral Capsule, Placebo - Obesity & Overweight, GLP - 1 | Not applicable | Recruiting | StudySetGo | 90 | 2026-09-01 | 2026-10-19 |
| Exploring the Influence of Glucagon-like Peptide -1 (GLP-1) Medications on Food Cravings, Food Selection, and Food Intake Following Exposure to Food Advertisements Food advertisements, Tech advertisements - GLP - 1 | Not applicable | Not yet recruiting | Penn State University | 50 | 2026-09-01 | 2026-10-07 |
| Lifestyle Change Implementation Research Network at PRC at UMass Chan Digital Lifestyle Coaching Program - GLP - 1 | Not applicable | Recruiting | University of Massachusetts, Worcester | 220 | 2026-07-22 | 2026-09-24 |
| Combatting Muscle Loss in Obese Adult Patients on GLP-1 Medications Through Dietary Counseling and Exercise During Treatment Evaluates Whether a 12-week Exercise and Individualized Nutrition Program Can Reduce Muscle and Bone Loss and Improve Strength, Fitness, and Function in Obese Adults on GLP-1 Semaglutide, Dietary Counseling, Exercise - GLP - 1, Obesity & Overweight | Phase 4 | Not yet recruiting | William Marsh Rice University | 20 | 2026-04-06 | 2026-04-28 |
| Effects of Tirzepatide on Muscle and Vascular Health in Obese Older Adults Tirzepatide - Obesity Prevention, Sarcopenia in Elderly | Phase 2 | Recruiting | The University of Texas Health Science Center at San Antonio | 20 | 2026-04-01 | 2026-04-15 |
| Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder Group Therapy Program, semaglutide, Phentermine-Topiramate - Bipolar I Disorder, Bipolar II Disorder | Phase 4 | Recruiting | Mayo Clinic | 100 | 2026-01-19 | 2026-03-11 |
| Multivitamin Impact on Micronutrient Status in GLP-1 Users: A Randomized Trial Multivitamin Supplementation, Placebo - Weight Loss, Nutritional Deficiencies | Not applicable | Enrolling by invitation | Erasmus Medical Center | 246 | 2025-12-16 | 2025-11-19 |
| The Impact of GLP Medication on Colonoscopy Bowel Preparation Quality Continue GLP/GIP - GLP - 1, Bowel Preparation for Colonoscopy | Phase 4 | Recruiting | The Cleveland Clinic | 132 | 2025-08-01 | 2025-12-04 |
| Bone Metabolism in 12-21 Year Olds Undergoing Glucagon Like Peptide (GLP)-1 Receptor Agonist Therapy GLP-1 receptor agonist, Lifestyle intervention - Obesity in Children, Bone Strength | Phase 2 | Recruiting | University of Virginia | 120 | 2025-07-31 | 2026-04-17 |
| FIT-COACH: Fitbit Intervention With Coordinated Health Coaching and PCP Support Health Coach/Fitbit - GLP - 1, Diabetes | Not applicable | Completed | University of Massachusetts, Worcester | 15 | 2025-03-18 | 2025-12-18 |
| The Comparison of PYY, Ghrelin, GLP1, Glucose Level, Level of Satiety, and Ad Libitum Intake in Obese and Non-Obese Patients After Breakfast With Balanced Macronutrient Composition Diet with balance composition to know the effect of a meal to gut hormones in obese and non obese women - PYY, Ghrelin | Not applicable | Completed | Universitas Indonesia | 40 | 2010-10-01 | 2018-10-10 |
Obesity (10) · Overweight (4) · Weight Loss (4) · Diabetes Mellitus (2) · Motor Activity (2) · Arthritis (1) · Bipolar Disorder (1) · Body Weight (1) · Cardiovascular Diseases (1) · Malnutrition (1) · Muscular Atrophy (1) · Pediatric Obesity (1) · Psychotic Disorders (1) · Sarcopenia (1)
Nutritional and Metabolic Diseases (11) · Pathological Conditions, Signs and Symptoms (11) · Signs and Symptoms (11) · Body Weight (10) · Nutrition Disorders (10) · Overnutrition (10) · Overweight (6) · Body Weight Changes (4) · Atrophy (2) · Behavior (2) · Endocrine System Diseases (2) · Glucose Metabolism Disorders (2) · Metabolic Diseases (2) · Nervous System Diseases (2) · Neurologic Manifestations (2)
semaglutide (2) · Adiposity (1) · Behavior Therapy (1) · Diet (1) · Exercise (1) · Glucagon-Like Peptide-1 Receptor Agonists (1) · Naltrexone-Bupropion combination (1) · Nutrition Assessment (1) · Qsymia (1) · Tirzepatide (1) · ubiquinol (1)
University of Massachusetts, Worcester (2) · Erasmus Medical Center (1) · Mayo Clinic (1) · Nova Scotia Health Authority (1) · Penn State University (1) · StudySetGo (1) · The Cleveland Clinic (1) · The University of Texas Health Science Center at San Antonio (1) · Universitas Indonesia (1) · University of Alabama at Birmingham (1) · University of Virginia (1) · William Marsh Rice University (1)
United States (8) · Canada (1) · Indonesia (1) · Netherlands (1) · United Kingdom (1)
Elena Volpi, MD, PhD (1) · Holly Wyatt, MD (1) · Jamie Faro, PhD (1) · Madhusmita Misra, MD, MPH (1) · Mark A Frye, M.D. (1) · Shreya Rao, MD, MPH (1) · Tiffany Cortes, MD (1)
PMID 31565876, PMID 33269530, PMID 36568085, PMID 38454010, PMID 39040467, PMID 39175746, PMID 39295512, PMID 39722834, PMID 39892489
R01DK147319 (1), R01HD118635 (1), U48DP006955 (1)