15 completed. 15 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 15 | Completed 15 |
Follow GERD: new trials by email Literature Review of GERD trials Research Report on GERD
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Compare Pharmacokinetics, Pharmacodynamics and Safety of UI059 and UIC202201 in Healthy Subjects UI059, UIC202201 - GERD | Phase 1 | Completed | Korea United Pharm. Inc. | 8 | 2023-10-08 | 2023-11-21 |
| Investigate Linaprazan Glurate/Linaprazan in Healthy Subjects linaprazan glurate 25 mg QD, linaprazan glurate 50 mg QD, linaprazan glurate 75 mg QD - GERD | Phase 1 | Completed | Cinclus Pharma Holding AB | 75 | 2023-01-26 | 2025-05-07 |
| A Study to Investigate the Effect of Food on the PK, PD of CKD-381 in Healthy Volunteers CKD-381 - GERD | Phase 1 | Completed | Chong Kun Dang Pharmaceutical | 28 | 2021-04-21 | 2021-08-18 |
| A Study to Compare PK, PD and Safety of UI058 and UIC202004 in Healthy Subjects administration of UI058, administration of UIC202004 - GERD | Phase 1 | Completed | Korea United Pharm. Inc. | 41 | 2021-02-03 | 2024-07-03 |
| Clinical Trial to Assess the PK/PD of YYD601 20mg After Oral Administration if Healthy Adult Subjects (Phase1) YYD601 20mg, Nexium tab 20mg - GERD | Phase 1 | Completed | Yooyoung Pharmaceutical Co., Ltd. | 28 | 2019-07-08 | 2021-05-11 |
| A Study to Compare PK, PD and Safety of CKD-381 and D026 in Healthy Subjects CKD-381, D026 - GERD | Phase 1 | Completed | Chong Kun Dang Pharmaceutical | 41 | 2018-06-27 | 2018-10-12 |
| A Study to Compare PK and Safety of CKD-381 and D026 in Healthy Male Subjects CKD-381(formulation I), CKD-381(formulation II), D026(Nexium 40mg) - GERD | Phase 1 | Completed | Chong Kun Dang Pharmaceutical | 18 | 2018-03-02 | 2018-05-24 |
| PK/PD Clinical Trial of YYD601 in Healthy Adult Male YYD601 1, YYD601 2, YYD601 3 - GERD | Phase 1 | Completed | Yooyoung Pharmaceutical Co., Ltd. | 30 | 2017-09-19 | 2018-06-15 |
| A Study to Compare PK, PD and Safety of CKD-381 in Healthy Subjects CKD-381, Nexium - GERD | Phase 1 | Completed | Chong Kun Dang Pharmaceutical | 41 | 2017-06-20 | 2017-11-21 |
| Can Quercetin Increase Claudin-4 and Improve Esophageal Barrier Function in GERD? Quercetin - Gastroesophageal Reflux Disease, GERD | Phase 1 | Completed | University of North Carolina, Chapel Hill | 26 | 2014-08-01 | 2016-12-20 |
| Pharmacokinetics of Pantoprazole and CYP2C19 Activity in Children and Adolescents With GERD: A Pilot Study Pantoprazole - Obesity, GERD | Phase 1 | Completed | Children's Mercy Hospital Kansas City | 71 | 2013-06-01 | 2021-12-03 |
| A Study of the Effect of ONO-8539 on Oesophageal Pain Hypersensitivity in Patients With Non-erosive Reflux Disease ONO-8539, Placebo - GERD | Phase 1 | Completed | Ono Pharmaceutical Co., Ltd. | 14 | 2012-12-01 | 2015-10-14 |
| A Pharmacokinetic and Safety Study of Single and Multiple Doses of Rabreprazole in Pediatric Patients With Gastroesophageal Reflux Disease (GERD) 1 to 11 Years Old, Inclusive Rabeprazole sodium - GERD | Phase 1 | Completed | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | 31 | 2008-03-01 | 2011-01-10 |
| Acid Reflux and Stromal Fibroblasts in Barrett's Esophagus Endoscopy and pH study - Barrett's Esophagus, GERD | Phase 1 | Completed | Mayo Clinic | 16 | 2007-08-01 | 2013-01-17 |
| A Study to Monitor Intragastric pH in Patients Taking Rabeprazole vs. Patients Taking Pantoprazole rabeprazole sodium - GERD | Phase 1 | Completed | Janssen-Ortho Inc., Canada | 37 | 2005-10-01 | 2012-12-10 |
Gastroesophageal Reflux (15) · Barrett Esophagus (1) · Obesity (1)
Deglutition Disorders (15) · Digestive System Diseases (15) · Esophageal Diseases (15) · Esophageal Motility Disorders (15) · Gastrointestinal Diseases (15) · Body Weight (1) · Neoplasms (1) · Nutrition Disorders (1) · Nutritional and Metabolic Diseases (1) · Overnutrition (1) · Overweight (1) · Pathological Conditions, Signs and Symptoms (1) · Precancerous Conditions (1) · Signs and Symptoms (1)
Esomeprazole (3) · Rabeprazole (2) · BID protein, human (1) · Drugs, Investigational (1) · Endoscopy (1) · ONO-8539 (1) · Pantoprazole (1) · Quercetin (1)
Chong Kun Dang Pharmaceutical (4) · Korea United Pharm. Inc. (2) · Yooyoung Pharmaceutical Co., Ltd. (2) · Children's Mercy Hospital Kansas City (1) · Cinclus Pharma Holding AB (1) · Janssen-Ortho Inc., Canada (1) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (1) · Mayo Clinic (1) · Ono Pharmaceutical Co., Ltd. (1) · University of North Carolina, Chapel Hill (1)
South Korea (8) · United States (3) · Belgium (1) · Slovenia (1) · United Kingdom (1)
Choon Ok Kim, MD (1) · Craig Friesen, MD (1) · Kyung Sang Yu, M.D (1) · Kyung Sang Yu, M.D., Ph.D. (1) · Kyungsang Yu, M.D., Ph.D. (1) · Min Kyu Park, Dr (1) · Minkyu Park, Dr (1) · Nicholas Shaheen, MD, MPH (1) · Prasad G Iyer, M.D. (1) · Tanja Turk, M.Pharm (1)
PMID 17116123, PMID 30257076, PMID 31564831, PMID 35281316, PMID 39803609
R21DK097529 (1)