2 terminated. 2 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 2 | Terminated 2 |
| Phase 2 | 1 | Terminated 1 |
Follow Frontotemporal Lobar Degeneration: new trials by email Literature Review of Frontotemporal Lobar Degeneration trials Research Report on Frontotemporal Lobar Degeneration
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Open-label Extension (OLE) Study of WVE-004 in Patients With C9orf72-associated Amyotrophic Lateral Sclerosis (ALS) and/or Frontotemporal Dementia (FTD) WVE-004 10 mg Q12W - Amyotrophic Lateral Sclerosis, Frontotemporal Dementia | Phase 1 / Phase 2 | Terminated | Wave Life Sciences USA, Inc. | 8 | 2022-12-14 | 2026-09-09 |
| BIIB092 in Primary Tauopathies: CBS, nfvPPA, sMAPT, and TES BIIB092, Placebo - Primary Tauopathies, Corticobasal Degeneration Syndrome | Phase 1 | Terminated | University of California, San Francisco | 22 | 2018-09-12 | 2019-12-19 |
Amyotrophic Lateral Sclerosis (1) · Color Vision Defects (1) · Frontotemporal Dementia (1) · Pick Disease of the Brain (1) · Primary Progressive Nonfluent Aphasia (1)
Brain Diseases (2) · Central Nervous System Diseases (2) · Dementia (2) · Mental Disorders (2) · Metabolic Diseases (2) · Nervous System Diseases (2) · Neurocognitive Disorders (2) · Neurodegenerative Diseases (2) · Nutritional and Metabolic Diseases (2) · Proteostasis Deficiencies (2) · TDP-43 Proteinopathies (2) · Aphasia (1) · Aphasia, Primary Progressive (1) · Communication Disorders (1)
gosuranemab (1)
University of California, San Francisco (1) · Wave Life Sciences USA, Inc. (1)
Netherlands (1) · United Kingdom (1) · United States (1)