2300 completed. 2300 Phase 3, 248 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 2300 | Completed 2300 |
| Phase 2 | 248 | Completed 248 |
Follow Endocrine System Diseases: new trials by email Literature Review of Endocrine System Diseases trials Research Report on Endocrine System Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Adjuvant Therapy With Letrozole in Induction of Ovulation With Polycystic Ovarian Syndrome Metformin, Dapagliflozin, Dapagliflozin/Metformin - Polycystic Ovary | Phase 3 | Completed | Beni-Suef University | 200 | 2026-03-30 | 2026-06-02 |
| A Research Study to See if Two Different Formulations of Oral Semaglutide Are Equally Safe and Effective in Reducing the Blood Sugar Level in Japanese People With Type 2 Diabetes Oral semaglutide - Type 2 Diabetes | Phase 3 | Completed | Novo Nordisk A/S | 267 | 2025-12-01 | 2026-08-13 |
| Comparative Study of Different Weekly GLP-1 Receptor Agonists Among Diabetic and Non-Diabetic Patients: Clinical Trial Dulaglutide 1.5 MG/ML, Semaglutide 2 mg/1.5 ml (1.34 mg/ml), prefilled pen-injector for subcutaneous injection solution, Tirzepatide is administered as part of routine clinical care for obesity management, according to standard prescribing practices. Dosing and treatment duration are determined by the treating physician - Obese Diabetics, Obese Non Diabetic | Phase 3 | Completed | Zagazig University | 159 | 2025-10-18 | 2026-09-15 |
| A Safety, Tolerability and Pharmacokinetics Study of VRDN-003 in Participants With Thyroid Eye Disease (TED) VRDN-003, Autoinjector - Thyroid Eye Disease | Phase 3 | Completed | Viridian Therapeutics, Inc. | 87 | 2025-07-01 | 2026-06-25 |
| Inhaled Insulin vs Rapid-acting Injections for Post-meal Glucose Control in Women With Gestational Diabetes Inhaled Technosphere Insulin - Diabetes, Gestational, Pregnancy Complications | Phase 2 / Phase 3 | Completed | Jaeb Center for Health Research | 30 | 2025-06-02 | 2026-10-19 |
| The Combined Effect of N-Acetyl Cysteine and Metformin in Polycystic Ovary Syndrome Patients N-acetyl cysteine, Metfomin - Polycystic Ovary Syndrome | Phase 3 | Completed | Cairo University | 102 | 2025-03-01 | 2026-10-21 |
| Automated Insulin Delivery for Inpatients With Dysglycemia AID system with Remote Real-Time CGM, Standard of Care Insulin Therapy + CGM - Type 1 Diabetes, Type 2 Diabetes | Phase 3 | Completed | Emory University | 130 | 2025-01-22 | 2025-11-14 |
| Semaglutide in Women With Polycystic Ovary Syndrome and Obesity Metformin with Semaglutide - Polycystic Ovary Syndrome (PCOS) Women, Obesity | Phase 2 / Phase 3 | Completed | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | 31 | 2025-01-01 | 2026-10-07 |
| Impact of Myo-Inositol Alone vs Myo-Inositol Plus Metformin on Conception, Adherence, and Tolerability in PCOS Myoinositol, Metformin 1500 mg daily - PCOS (Polycystic Ovary Syndrome) | Phase 3 | Completed | PAEC general hospital | 120 | 2025-01-01 | 2026-01-07 |
| A Study of the Safety of Mibavademab in Pediatric and Adult Participants Switching From Metreleptin to Mibavademab for the Treatment of Generalized Lipodystrophy (GLD) mibavademab - Generalized Lipodystrophy | Phase 3 | Completed | Regeneron Pharmaceuticals | 9 | 2024-12-16 | 2026-07-29 |
| Role of Levothyroxine Supplementation in Delayed Recovery Following Cardiac Surgery L-thyroxine, Placebo Oral Tablet - Cardiac Surgery Intensive Care Treatment, Delayed Recovery From Anaesthesia | Phase 3 | Completed | Ain Shams University | 70 | 2024-11-30 | 2025-08-17 |
| SGLT2 Adjunct in T1D Empagliflozin (EMPA), Placebo - Type 1 Diabetes, Nephropathy, Diabetic | Phase 2 / Phase 3 | Completed | Ain Shams University | 86 | 2024-11-20 | 2026-05-18 |
| the Efficacy and Safety of HRS9531 Injection in Subjects With Type 2 Diabetes， Inadequately Controlled With Diet and Exercise Alone HRS9531 Injection, HRS9531 Placebo Injection - Diabetes Mellitus, Type 2 | Phase 3 | Completed | Fujian Shengdi Pharmaceutical Co., Ltd. | 218 | 2024-11-08 | 2026-07-14 |
| The Experiment of Noiiglutide Injection in Type 2 Diabetes Patients Noiiglutide Injection, Noiiglutide Placebo - Type 2 Diabetes | Phase 3 | Completed | Jiangsu HengRui Medicine Co., Ltd. | 137 | 2024-11-06 | 2026-08-25 |
| A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin, SGLT2 Inhibitor or Both Cagrilintide, Semaglutide, Tirzepatide - Diabetes Mellitus, Type 2 | Phase 3 | Completed | Novo Nordisk A/S | 1023 | 2024-11-05 | 2026-10-19 |
| A Study of HRS9531 Versus Semaglutide Once Weekly as Add-on Therapy to Metformin Monotherapy or in Combination With SGLT2 Inhibitors in Participants With Type 2 Diabetes HRS9531 Injection, Semaglutide Injection - Type 2 Diabetes | Phase 3 | Completed | Fujian Shengdi Pharmaceutical Co., Ltd. | 884 | 2024-10-31 | 2026-07-30 |
| Open-Label Extension Study of Setmelanotide Setmelanotide - Obesity Associated With Defects in Leptin-melanocortin Pathway | Phase 3 | Completed | Rhythm Pharmaceuticals, Inc. | 28 | 2024-10-21 | 2026-07-15 |
| A Study of HRS-7535 Compared With Dapagliflozin in Adult Participants With Type 2 Diabetes and Inadequately Controlled With Metformin HRS-7535 tablet, dapagliflozin tablet - Type 2 Diabetes | Phase 3 | Completed | Shandong Suncadia Medicine Co., Ltd. | 810 | 2024-09-27 | 2026-06-30 |
| A Study of HRS-7535 Compared With Placebo in Adult Participants With Type 2 Diabetes and Inadequately Controlled With Diet and Exercise HRS-7535 tablet, HRS-7535 placebo tablet - Type 2 Diabetes | Phase 3 | Completed | Shandong Suncadia Medicine Co., Ltd. | 284 | 2024-09-25 | 2026-05-22 |
| Effect of Sitagliptin on Polycystic Ovarian Syndrome Patients Sitagliptin 100mg - Polycystic Ovary Syndrome | Phase 2 / Phase 3 | Completed | Beni-Suef University | 80 | 2024-08-07 | 2026-09-01 |
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Diabetes Mellitus, Type 2 (1092) · Diabetes Mellitus (584) · Diabetes Mellitus, Type 1 (237) · Ovarian Neoplasms (102) · Pancreatic Neoplasms (92) · Insulin Resistance (80) · Obesity (73) · Polycystic Ovary Syndrome (61) · Diabetic Neuropathies (52) · Hypertension (50) · Carcinoma, Ovarian Epithelial (48) · Fallopian Tube Neoplasms (47) · Diabetic Retinopathy (41) · Dwarfism, Pituitary (40) · Hypogonadism (40)
Nutritional and Metabolic Diseases (1626) · Metabolic Diseases (1595) · Glucose Metabolism Disorders (1527) · Diabetes Mellitus (1081) · Urogenital Diseases (356) · Female Urogenital Diseases and Pregnancy Complications (337) · Neoplasms (318) · Female Urogenital Diseases (316) · Pathological Conditions, Signs and Symptoms (289) · Gonadal Disorders (287) · Immune System Diseases (282) · Neoplasms by Site (268) · Endocrine Gland Neoplasms (265) · Autoimmune Diseases (261)
Metformin (254) · Insulin Glargine (173) · Sitagliptin Phosphate (115) · Vildagliptin (71) · Insulin Aspart (69) · glimepiride (65) · Pioglitazone (64) · dapagliflozin (63) · Liraglutide (62) · semaglutide (58) · Gemcitabine (57) · insulin degludec (56) · Exenatide (54) · Insulin Detemir (45) · Insulin (44)
Novo Nordisk A/S (216) · Eli Lilly and Company (121) · AstraZeneca (117) · Sanofi (93) · Merck Sharp & Dohme LLC (76) · Novartis Pharmaceuticals (53) · Boehringer Ingelheim (50) · Takeda (48) · Novartis (38) · GlaxoSmithKline (30) · Hoffmann-La Roche (27) · Pfizer (25) · Amgen (24) · Astellas Pharma Inc (14) · Ipsen (14)
United States (1021) · Germany (452) · Canada (402) · Spain (337) · United Kingdom (320) · France (319) · Italy (316) · Poland (300) · Mexico (279) · Russia (278) · Japan (260) · Hungary (241) · South Korea (220) · India (213) · Australia (212)
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