2307 completed, 327 unknown, 316 terminated, 248 recruiting. 3503 Phase 3, 452 Phase 2.
Follow Endocrine System Diseases: new trials by email Literature Review of Endocrine System Diseases trials Research Report on Endocrine System Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Testosterone Therapy With or Without Finasteride After Spinal Cord Injury: TRT-SCI Trial testosterone cypionate, finasteride, placebo injection - Spinal Cord Injury, Spinal Cord Injuries | Phase 2 / Phase 3 | Not yet recruiting | VA Office of Research and Development | 300 | 2027-10-01 | 2026-08-04 |
| Postpartum Semaglutide to Reduce Cardiometabolic Risk After Gestational Diabetes Mellitus Semaglutide (Wegovy) weekly injection - Gestational Diabetes Mellitus (GDM), Metabolic Syndrome | Phase 2 / Phase 3 | Not yet recruiting | University of Massachusetts, Worcester | 226 | 2027-09-01 | 2026-09-28 |
| Open-Label Extension Study of MHB018A in Patients With Thyroid Eye Disease MHB018A injection - Thyroid Eye Disease (TED) | Phase 3 | Not yet recruiting | Minghui Pharmaceutical (Hangzhou) Ltd | 219 | 2027-07-01 | 2026-06-04 |
| Clinical Trial of DN022150 Combined With AG Chemotherapy as First-line Treatment for Locally Advanced or Metastatic Pancreatic Cancer With KRAS G12D Mutation DN022150+AG( Stage I ）, DN022150+AG（Stage II）, placebo+AG（Stage II） - Pancreatic Cancer, Pancreatic Carcinoma | Phase 2 / Phase 3 | Not yet recruiting | Jiangxi Kvvit Pharmaceutical Co., Ltd. | 465 | 2027-06-06 | 2026-06-18 |
| Comparison of the Euploid Rate of Blastocyst Between PPOS and GnRH Antagonist Protocol in Women With PCOS Undergoing PGT-A GnRH antagonist, MPA - Preimplantation Genetic Testing, Progestin-primed Ovarian Stimulation | Phase 3 | Not yet recruiting | ShangHai Ji Ai Genetics & IVF Institute | 204 | 2027-06-01 | 2026-11-09 |
| CKM For Safe Use of SGLT2i in Type 1 Diabetes Sotagliflozin Low Dose, Sotagliflozin High Dose, Dual Continuous Glucose and Ketone Monitor - Type 1 Diabetes (T1D) | Phase 3 | Not yet recruiting | University of California, San Diego | 52 | 2027-04-01 | 2026-11-04 |
| A Study of Raludotatug Deruxtecan (R-DXd) With or Without Bevacizumab as Maintenance Therapy in Second-Line Platinum-Sensitive Recurrent Ovarian Cancer (REJOICE-Ovarian03) R-DXd, Bevacizumab - Fallopian Tube Cancer, Primary Peritoneal Cancer | Phase 3 | Not yet recruiting | Daiichi Sankyo | 600 | 2027-03-31 | 2026-11-13 |
| Phase 3 Long Term Safety Extension Study of LUM-201 in Children With Growth Hormone Deficiency LUM-201 - Growth Hormone Deficiency (GHD) | Phase 3 | Not yet recruiting | Lumos Pharma | 150 | 2027-02-01 | 2026-07-08 |
| A Study to Evaluate the Effectiveness and Safety of the Drug AZD6234 for Managing Weight in Adults Who Are Obese or Overweight. These Participants May or May Not Also Have Type 2 Diabetes AZD6234, Placebo - Obesity, Overweight | Phase 3 | Not yet recruiting | AstraZeneca | 330 | 2027-01-04 | 2026-11-06 |
| A Study Comparing MRG004A Plus Best Supportive Care Versus Placebo and Best Supportive Care in the Treatment of Patients With Advanced Pancreatic Cancer MRG004A plus best supportive care, Placebo plus best supportive care - Advanced Pancreatic Cancer | Phase 3 | Not yet recruiting | Lepu Biopharma Co., Ltd. | 231 | 2027-01-01 | 2026-05-15 |
| Verapamil In Preclinical Type 1 Diabetes Verapamil 120 Mg/24 Hours Oral Capsule, Extended Release, Placebo, blood sampling - Type 1 Diabetes | Phase 2 / Phase 3 | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 50 | 2027-01-01 | 2026-10-22 |
| Diabetes Prevention Through Genetics, Familial History and Behavior Change LEGACY DPP, DPP - Prediabetes, Weight Loss | Phase 2 / Phase 3 | Not yet recruiting | Morehouse School of Medicine | 400 | 2027-01-01 | 2026-10-20 |
| PDS Versus NACT-IDS in AI-Selected Advanced Epithelial Ovarian Cancer Upfront cytoreductive surgery, Interval debulking surgery, Platinum-based chemotherapy - Epithelial Ovarian Cancer, Fallopian Tube Cancers | Phase 2 / Phase 3 | Not yet recruiting | Shanghai Gynecologic Oncology Group | 534 | 2026-12-31 | 2026-11-12 |
| Phase 3 Study of INCB123667 Plus Bevacizumab Versus Bevacizumab Alone as First-Line Maintenance Therapy in Ovarian Cancer Overexpressing Cyclin E1 INCB123667, Bevacizumab, Placebo - Ovarian Cancer | Phase 3 | Not yet recruiting | Incyte Corporation | 590 | 2026-12-01 | 2026-10-02 |
| A Clinical Study to Evaluate the Effects of Enicepatide Versus Tirzepatide in Participants With Type 2 Diabetes and Inadequate Blood Sugar Control on Oral Glucose-Lowering Medications Enicepatide, Tirzepatide - Type 2 Diabetes Mellitus | Phase 3 | Not yet recruiting | Hoffmann-La Roche | 948 | 2026-12-01 | 2026-10-22 |
| A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, Type 2 Diabetes, and Increased Cardiovascular Risk Eloralintide, Placebo - Obesity, Overweight | Phase 3 | Not yet recruiting | Eli Lilly and Company | 3000 | 2026-12-01 | 2026-11-03 |
| A Study of QLS5132 in Platinum-Resistant Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer QLS5132, Liposomal Doxorubicin, Paclitaxel - Epithelial Ovarian Cancer, Fallopian Tube Cancer | Phase 3 | Not yet recruiting | Qilu Pharmaceutical Co., Ltd. | 420 | 2026-12-01 | 2026-11-09 |
| Alpha-Lipoic Acid Added to Dapagliflozin and Insulin Resistance in Type 2 Diabetes Alpha-Lipoic Acid (ALA), Placebo - Diabetes Mellitus, Type 2, Insulin Resistance Syndrome | Phase 3 | Not yet recruiting | Fayoum University | 70 | 2026-12-01 | 2026-11-12 |
| iSGLT2 Inhibitor and a iDPP -4 Inhibitor in Treatment of Type 2 Diabetes Mellitus in Patients Treated With Metformin (TRIAD) N0892, Januvia® + Glifage XR® + Placebo, Forxiga® + Glifage XR® + Placebo - Diabetes Mellitus, Type 2 | Phase 3 | Withdrawn | Eurofarma Laboratorios S.A. | 2026-11-30 | 2025-12-18 | |
| A Research Study Investigating How Well Zenagamtide at Lower Dose Levels Lowers Blood Sugar and Body Weight Compared to Semaglutide at Lower Dose Levels in People With Type 2 Diabetes Treated With Metformin, Sodium-Glucose Cotransporter 2 Inhibitors (SGLT2i), or Both Zenagamtide, Semaglutide, Placebo zenagamtide - Diabetes Mellitus, Type 2 | Phase 3 | Not yet recruiting | Novo Nordisk A/S | 1060 | 2026-11-10 | 2026-11-12 |
Showing 20 of 3503. Sign in to see all of them.
Diabetes Mellitus, Type 2 (1435) · Diabetes Mellitus (782) · Diabetes Mellitus, Type 1 (316) · Ovarian Neoplasms (262) · Pancreatic Neoplasms (216) · Obesity (131) · Insulin Resistance (110) · Fallopian Tube Neoplasms (109) · Carcinoma, Ovarian Epithelial (98) · Polycystic Ovary Syndrome (80) · Diabetic Neuropathies (76) · Hypertension (75) · Diabetic Foot (73) · Diabetic Retinopathy (70) · Dwarfism, Pituitary (57)
Nutritional and Metabolic Diseases (2218) · Metabolic Diseases (2173) · Glucose Metabolism Disorders (2081) · Diabetes Mellitus (1530) · Urogenital Diseases (687) · Neoplasms (684) · Female Urogenital Diseases and Pregnancy Complications (656) · Neoplasms by Site (627) · Female Urogenital Diseases (623) · Endocrine Gland Neoplasms (618) · Gonadal Disorders (547) · Pathological Conditions, Signs and Symptoms (502) · Genital Diseases (456) · Genital Diseases, Female (418)
Metformin (324) · Insulin Glargine (185) · Sitagliptin Phosphate (134) · Gemcitabine (123) · Paclitaxel (106) · semaglutide (94) · Insulin Aspart (89) · dapagliflozin (89) · glimepiride (82) · Carboplatin (81) · Pioglitazone (76) · Vildagliptin (74) · Liraglutide (71) · Insulin (65) · Bevacizumab (63)
Novo Nordisk A/S (246) · AstraZeneca (151) · Eli Lilly and Company (140) · Sanofi (111) · Merck Sharp & Dohme LLC (98) · Takeda (64) · Novartis Pharmaceuticals (60) · Boehringer Ingelheim (53) · Pfizer (44) · Novartis (39) · GlaxoSmithKline (37) · Amgen (36) · Hoffmann-La Roche (33) · Ain Shams University (20) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (18)
United States (1474) · Germany (614) · Canada (572) · Spain (480) · United Kingdom (468) · France (465) · Italy (462) · China (434) · Poland (425) · Mexico (361) · Japan (352) · South Korea (347) · Russia (327) · Hungary (326) · Australia (311)
PMID 38770818, PMID 39963952, PMID 37185961, PMID 22236356, PMID 31903692, PMID 32998732, PMID 35044568, PMID 22913891, PMID 37407274, PMID 23010561, PMID 25504028, PMID 38682786, PMID 32267058, PMID 26580237, PMID 26894924, PMID 27402391, PMID 35472672, PMID 24517339, PMID 31606880, PMID 32306296, PMID 21450987, PMID 21883806, PMID 22193143, PMID 22234149, PMID 22862847, PMID 23130654, PMID 23186975, PMID 24170235, PMID 24786834, PMID 26232910, PMID 27977934, PMID 30615985, PMID 30880443, PMID 31769496, PMID 31797522, PMID 32324065, PMID 32324082, PMID 32372382, PMID 32501595, PMID 32648108, PMID 36542287, PMID 17878242, PMID 18093207, PMID 19245711, PMID 19491536, PMID 21209033, PMID 22055210, PMID 23748506, PMID 24561125, PMID 26121451
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