Endocrine System Diseases: Clinical Trials

313 trials for Endocrine System Diseases, newest first

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313 active not recruiting. 313 Phase 2, 76 Phase 1, 16 Phase 3.

By phase and status

PhaseTrialsStatus
Phase 2313Active not recruiting 313
Phase 176Active not recruiting 76
Phase 316Active not recruiting 16

Follow Endocrine System Diseases: new trials by email Literature Review of Endocrine System Diseases trials Research Report on Endocrine System Diseases

Trials (filtered) newest first · largest first

All 313 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Pre-emptive Insulin to Prevent High Glucose After a Knee Steroid Injection in Adults With Type 2 Diabetes
Insulin Isophane Human, NPH, Pre-emptive Algorithm, Triamcinolone Acetonide Knee Injection - Diabetes Mellitus, Type 2, Hyperglycemia Due to Type 2 Diabetes Mellitus
Phase 1 / Phase 2Active not recruitingShifa International Hospital1252026-08-102026-09-15
A Study to Assess the Efficacy, Safety and Tolerability of AT673 Co-administered With Semaglutide in Adult Participants With Type 2 Diabetes (T2D) and Overweight or Obesity
AT673 low dose, AT673 high dose, Placebo - Adults With Overweight/Obesity and Type 2 Diabetes
Phase 2Active not recruitingAntag Therapeutics1502026-06-192026-09-29
Generic Drugs (Dapagliflozin and Saxagliptin) Treat Type 2 Diabetes Patients With Controlled Cancers
Farxiga® (dapagliflozin) + Onglyza® (saxagliptin) + Metformin Oral Mix Treat type 2 diabetes, China Import (dapagliflozin) + China Import (saxagliptin) + Metformin Oral Mix Treat type 2 diabetes - Type 2 Diabetes
Phase 2 / Phase 3Active not recruitingHan Xu, M.D., Ph.D., FAPCR, Medical Director,, IRB Chair6002026-06-152026-08-27
A Phase II Clinical Study on the Efficacy and Safety of HRS-1780 in Participants With Primary Aldosteronism
HRS-1780 Tablets, Placebo - Primary Aldosteronism
Phase 2Active not recruitingShandong Suncadia Medicine Co., Ltd.612026-04-232026-10-13
A Study Comparing Safety and Efficacy of SHR-3167 Fixed-Dose Titration and Individualized-Dose Titration in Adults With Type 2 Diabetes Inadequately Controlled With Oral Antihyperglycemic Agents
SHR-3167 Injection, SHR-3167 Injection Placebo - Diabetes Mellitus, Type 2
Phase 2Active not recruitingJiangsu HengRui Medicine Co., Ltd.1022026-04-112026-06-04
Proteinuria in Normotensive Diabetic Patients: ARBs Alone or in Combination of SGLT2i
ARBs alone, ARBs in combination of SGLT2i - Proteinuria, Diabetes (DM)
Phase 2 / Phase 3Active not recruitingDr Mudassar Saeed Pansota602026-04-062026-05-14
Efficacy and Safety of Oral KAI-7535 in Adult Participants Living With Obesity or Overweight With at Least 1 Weight-Related Comorbidity
KAI-7535, Placebo - Obesity, Overweight
Phase 2Active not recruitingKailera3062026-04-062026-09-09
Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Who Are Not Achieving Glycemic Targets
icovamenib 100mg, Placebo - Type 2 Diabetes
Phase 2Active not recruitingBiomea Fusion Inc.642026-03-272026-08-28
A Clinical Study of Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes for the Treatment of Premature Ovarian Insufficiency
YT023, Control Arm (Conventional Therapy) - Premature Ovarian Insufficiency
Phase 1 / Phase 2Active not recruitingInternational Peace Maternity and Child Health Hospital602026-03-202026-04-03
GRK-Biased Activation Via β2-Adrenergic Receptors in Human Skeletal Muscle
ATR-258 - Overweight and Obesity
Phase 2Active not recruitingMorten Hostrup, PhD132026-02-192026-10-14
Study to Evaluate the Preliminary Efficacy of SKB264 and the Effect of Clarithromycin on the PK of SKB264 in OC
SKB264, Clarithromycin - Ovarian Epithelial Cancer
Phase 2Active not recruitingSichuan Kelun-Biotech Biopharmaceutical Co., Ltd.202026-01-162026-06-01
Trial of NP-G2-044 (Prilukae) Combined With PLD for Treatment of Platinum-Resistant Ovarian Cancer (ULTIMUS-1)
NP-G2-044, PLD - Platinum-resistant Ovarian Cancer
Phase 2 / Phase 3Active not recruitingNovita Pharmaceuticals, Inc.3802025-12-292026-03-09
TRPM8 Activators for Peripheral Neuropathy
Hand and Foot Mask - CIPN - Chemotherapy-Induced Peripheral Neuropathy, Diabetic Peripheral Neuropathy (DPN)
Phase 2Active not recruitingSHIANG-SUO HUANG602025-11-032026-05-15
Effectiveness Study of a Lifestyle Intervention Versus Metformin in Mothers With Recent Gestational Diabetes
Metformin Hcl 850Mg Tab, Lifestyle Intervention, Enhanced Lifestyle Intervention - Weight Loss, Gestational Diabetes Mellitus in Pregnancy
Phase 2Active not recruitingGeorge Washington University412025-10-272026-11-06
A Study Comparing Navlimetostat (BMS-986504) in Combination With Nab-paclitaxel and Gemcitabine Versus Placebo in Combination With Nab-paclitaxel and Gemcitabine in Participants With Untreated Metastatic Pancreatic Ductal Adenocarcinoma With Homozygous MTAP Deletion (MountainTAP-30)
Navlimetostat, Gemcitabine, Nab-paclitaxel - Pancreatic Ductal Adenocarcinoma
Phase 2 / Phase 3Active not recruitingBristol-Myers Squibb4702025-10-232026-06-03
A Study on the Safety and Clinical Efficacy of Guominkang in the Treatment of Diabetic Kidney Disease
Guominkang Granules, Standard Antihypertensive, Antidiabetic, and Lipid-Lowering Regimen - Diabetic Kidney Disease (DKD), Type 2 Diabetes
Phase 2Active not recruitingBeijing University of Chinese Medicine152025-10-202026-11-02
A Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type 2 Diabetes
Macupatide, Eloralintide, Macupatide Placebo - Obesity, Overweight
Phase 2Active not recruitingEli Lilly and Company2002025-10-162026-10-09
A Study of LY3938577 in Participants With Type 2 Diabetes Previously Treated With Basal Insulin
LY3938577, Degludec - Diabetes Mellitus, Type 2
Phase 2Active not recruitingEli Lilly and Company1002025-10-132026-07-13
Pharmacokinetics, Safety and Tolerability of Crinecerfont in Participants With Congenital Adrenal Hyperplasia Who Are Less Than 2 Years Old
Crinecerfont - Congenital Adrenal Hyperplasia
Phase 2Active not recruitingNeurocrine Switzerland GmbH72025-09-302026-08-28
Prehabilitation for EOC, Fallopian Tube, Primary Peritoneal Carcinoma and Pancreatic Cancer w/ NACT
Prehabilitation - Ovarian Cancer, Epithelial Ovarian Cancer
Phase 1 / Phase 2Active not recruitingCase Comprehensive Cancer Center12025-09-052026-09-15

Showing 20 of 313. Sign in to see all of them.

Narrower conditions

Pancreatic Neoplasms (87)  ·  Ovarian Neoplasms (78)  ·  Fallopian Tube Neoplasms (35)  ·  Diabetes Mellitus, Type 2 (31)  ·  Thyroid Neoplasms (27)  ·  Diabetes Mellitus, Type 1 (23)  ·  Carcinoma, Non-Small-Cell Lung (22)  ·  Colorectal Neoplasms (19)  ·  Carcinoma, Ovarian Epithelial (17)  ·  Stomach Neoplasms (17)  ·  Diabetes Mellitus (16)  ·  Breast Neoplasms (15)  ·  Endometrial Neoplasms (15)  ·  Melanoma (14)  ·  Neoplasm Metastasis (14)

Broader conditions

Neoplasms by Site (207)  ·  Endocrine Gland Neoplasms (204)  ·  Neoplasms (201)  ·  Urogenital Diseases (124)  ·  Female Urogenital Diseases and Pregnancy Complications (122)  ·  Female Urogenital Diseases (120)  ·  Digestive System Diseases (117)  ·  Digestive System Neoplasms (111)  ·  Gonadal Disorders (103)  ·  Urogenital Neoplasms (102)  ·  Genital Diseases (100)  ·  Pancreatic Diseases (96)  ·  Genital Diseases, Female (95)  ·  Adnexal Diseases (94)

Interventions

pembrolizumab (32)  ·  Gemcitabine (28)  ·  Albumin-Bound Paclitaxel (18)  ·  Magnetic Resonance Spectroscopy (18)  ·  Nivolumab (17)  ·  130-nm albumin-bound paclitaxel (16)  ·  Specimen Handling (15)  ·  Taxes (15)  ·  olaparib (15)  ·  Cisplatin (13)  ·  Biopsy (12)  ·  Carboplatin (12)  ·  Paclitaxel (12)  ·  Bevacizumab (11)  ·  Cyclophosphamide (11)

Sponsors

National Cancer Institute (NCI) (20)  ·  M.D. Anderson Cancer Center (16)  ·  Memorial Sloan Kettering Cancer Center (9)  ·  Eli Lilly and Company (7)  ·  Mayo Clinic (7)  ·  Massachusetts General Hospital (6)  ·  AbbVie (5)  ·  AstraZeneca (5)  ·  University Health Network, Toronto (5)  ·  BioMarin Pharmaceutical (4)  ·  Hoffmann-La Roche (4)  ·  CanariaBio Inc. (3)  ·  National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (3)  ·  Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (3)  ·  University of Chicago (3)

Countries

United States (221)  ·  Canada (46)  ·  Spain (38)  ·  Australia (33)  ·  China (33)  ·  United Kingdom (32)  ·  France (28)  ·  South Korea (26)  ·  Italy (25)  ·  Germany (24)  ·  Japan (20)  ·  Belgium (14)  ·  Poland (13)  ·  Puerto Rico (13)  ·  Taiwan (12)

Top investigators

Denise L Faustman, MD, PhD (3)  ·  Amit Oza, M.D. (2)  ·  Eric Sherman, MD (2)  ·  MD Verastem (2)  ·  Maria E Cabanillas (2)  ·  Meredith McKean, MD, MPH (2)

Results publications

PMID 31401903, PMID 31838007, PMID 37934000, PMID 40086048, PMID 10024506, PMID 10433086, PMID 10605821, PMID 10852253, PMID 11208527, PMID 11564949, PMID 11815483, PMID 12972423, PMID 15972654, PMID 16011702, PMID 16714282, PMID 17214730, PMID 1730582, PMID 17524725, PMID 18176934, PMID 18360702, PMID 19111249, PMID 19188144, PMID 19763038, PMID 19968980, PMID 19997760, PMID 20127992, PMID 20405312, PMID 20501948, PMID 20956533, PMID 21147316, PMID 21389784, PMID 22442300, PMID 23250488, PMID 24327518, PMID 25403204, PMID 25481791, PMID 25554012, PMID 26397425, PMID 26586415, PMID 27424289, PMID 28053024, PMID 28114552, PMID 28324110, PMID 28672195, PMID 28841916, PMID 2891995, PMID 29118225, PMID 29223478, PMID 29383130, PMID 29506054

NIH funding

2023 (11), 2015 (5), U10CA180868 (5), 2019 (3), P50CA136393 (3), U10CA180820 (3), U10CA180821 (3), 2017 (2), 2018 (2), 2025 (2), N01CM00032 (2), N01CM00071 (2), P30CA008748 (2), U10CA180886 (2), U10CA180888 (2)