2749 completed. 2749 Phase 1, 517 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 2749 | Completed 2749 |
| Phase 2 | 517 | Completed 517 |
Follow Endocrine System Diseases: new trials by email Literature Review of Endocrine System Diseases trials Research Report on Endocrine System Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Food Effect and Multiple-Dose Study of Chiglitazar/Metformin Extended-Release Tablets Chiglitazar/Metformin extended-release tablets under fasting conditions, Chiglitazar/Metformin extended-release tablets after a high-fat meal, multiple-dose of Chiglitazar/Metformin extended-release tablets - T2DM (Type 2 Diabetes Mellitus) | Phase 1 | Completed | Chipscreen Biosciences, Ltd. | 28 | 2026-09-10 | 2026-11-05 |
| A Phase 1 Study to Evaluate the Relative Bioavailability of Octreotide Acetate Tablets(T25) Compared to MYCAPSSA® and The Food Effect on Pharmacokinetics Of Octreotide Acetate Tablets(T25) T25-Fast, Mycapssa, T25-Fed - Acromegaly | Phase 1 | Completed | Triastek (Shanghai) Limited | 18 | 2026-06-25 | 2026-09-16 |
| Bioequivalence Study to Compare Empagliflozin/Linagliptin/Metformin HCl25 mg/5 mg/1000 mg Extended Release Tablet Versus Trijardy® XR 25 mg/5 mg/1000 mg Extended- Release Tablets Empagliflozin/Linagliptin/Metformin HCl Extended Release Tablet, Trijardy® XR Tablets - Type 2 Diabetes Mellitus (T2DM), Cardiovascular Diseases | Phase 1 | Completed | Humanis Saglık Anonim Sirketi | 36 | 2026-06-07 | 2026-10-13 |
| A Study to Evaluate Different Administration Conditions and the Food Effect of MWN109 Tablets in Chinese Participants MWN109 Tablets - Type 2 Diabetes Mellitus (T2DM), Overweight , Obesity | Phase 1 | Completed | Shanghai Minwei Biotechnology Co., Ltd | 162 | 2026-05-24 | 2026-09-03 |
| Phase I Study to Evaluate the Pharmacokinetics and Safety After Co-administration of L03RD1 and L03RD2 or Administration of L03TD1 in Healthy Volunteers L03RD1, L03RD2, L03TD1 - Type 2 Diabetes Mellitus (T2DM) | Phase 1 | Completed | Celltrion | 48 | 2026-05-09 | 2026-07-28 |
| Bioequivalence Study to Compare Empagliflozin/ Metformin 25 mg/ 1000 mg Extended-Release Tablet Versus Synjardy XR Tablets 25mg/1000mg Empagliflozin / Metformin Extended-Release Tablet, Synjardy XR tablets - Type 2 Diabetes Mellitus (T2DM) | Phase 1 | Completed | Humanis Saglık Anonim Sirketi | 40 | 2026-05-07 | 2026-07-09 |
| A Study to Investigate the Effect of AZD5004 on Mitiglinide and Pioglitazone in Healthy Participants AZD5004, Mitiglinide, Pioglitazone - Healthy Participants | Phase 1 | Completed | AstraZeneca | 32 | 2026-03-13 | 2026-07-13 |
| Bioequivalence Study to Compare Empagliflozin/Linagliptin/Metformin HCl 25 mg/5 mg/1000 mg Extended Release Tablet Versus Trijardy® XR 25 mg/5 mg/1000 mg Extended- Release Tablets Empagliflozin/Linagliptin/Metformin HCl Extended Release Tablet, Trijardy® XR Tablets - Type 2 Diabetes Mellitus (T2DM), Cardiovascular Diseases | Phase 1 | Completed | Humanis Saglık Anonim Sirketi | 36 | 2026-03-07 | 2026-07-08 |
| A Study to Investigate the Pharmacokinetics of Different Formulations and Safety of AZD5004 in Healthy Participants Aged 18 to 55 Years AZD5004 - Healthy Participants | Phase 1 | Completed | AstraZeneca | 65 | 2026-03-05 | 2026-06-10 |
| A Food-Effect Study of CX11 in Healthy Participants CX11 (VCT220) - Obesity & Overweight, Type 2 Diabetes | Phase 1 | Completed | Vincentage Pharma Co., Ltd | 32 | 2026-03-04 | 2026-10-13 |
| A Single Bolus, 12-hour Euglycemic Clamp Study of the Safety, Pharmacokinetics (PK) and Glucodynamics (GD) of Intraperitoneal (IP) Portal Insulin U-500 Portal Insulin U-500, Humulin R U-500, Lyumjev U-100 Insulin - Type 1 Diabetes | Phase 1 | Completed | Portal Diabetes, Inc. | 29 | 2026-02-10 | 2026-11-04 |
| Bioequivalence Study to Compare Imeglimin HCl 500 mg Film Coated Tablets Versus Twymeeg Tablets 500 mg Imeglimin Hydrochloride Film Coated Tablet, TWYMEEG® Tablets - Type 2 Diabetes | Phase 1 | Completed | Humanis Saglık Anonim Sirketi | 40 | 2026-02-06 | 2026-07-08 |
| Effects of Different Administration Routes of Dexmedetomidine on Postoperative Sleep Quality in Patients Undergoing Thyroidectomy Dexmedetomidine (DEX), Saline - Thyroid Diseases | Phase 1 / Phase 2 | Completed | The Second People's Hospital of Huai'an | 120 | 2026-01-05 | 2026-09-11 |
| A Study to Evaluate the Effect of Fasting Duration and Dulaglutide (LY2189265) Withholding on Gastric Retention in Participants With Type 2 Diabetes Mellitus Dulaglutide - Type 2 Diabetes Mellitus (T2DM) | Phase 1 | Completed | Eli Lilly and Company | 20 | 2025-12-29 | 2026-08-21 |
| A Clinical Trial of MK-1403 in Participants With Type 2 Diabetes Mellitus (MK-1403-006) MK-1403 + additive coformulation, Placebo + additive coformulation - Diabetes Mellitus, Type 2 | Phase 1 | Completed | Merck Sharp & Dohme LLC | 53 | 2025-12-22 | 2026-09-15 |
| A Research Study of a New Medicine NNC0363-1063 in Participants With Type 1 Diabetes NNC0363-1063 - Diabetes Mellitus, Type 1 | Phase 1 | Completed | Novo Nordisk A/S | 36 | 2025-12-16 | 2026-06-05 |
| A 2-part, Phase 1b Clinical Study Designed to Evaluate the Safety, PK, and Efficacy of CRB-913 in Participants With Obesity CRB-913, Placebo - Obese But Otherwise Healthy Participants | Phase 1 | Completed | Corbus Pharmaceuticals Inc. | 254 | 2025-12-04 | 2026-10-09 |
| Clinical Study to Evaluate the Pharmacokinetics and Safety of CKD-383 0.25/12.5/1000mg in Healthy Volunteers CKD-383 0.25/12.5/1000mg, CKD-501, D745, D150 - Type 2 Diabetes | Phase 1 | Completed | Chong Kun Dang Pharmaceutical | 30 | 2025-10-30 | 2025-12-26 |
| Subcutaneous Pharmacokinetic Evaluation of Monomeric Insulin and Lyumjev in Adults With Type 1 Diabetes Diluted Humalog U-200 Insulin, Diluted U-500 Humulin Insulin, Lyumjev U-100 Insulin - Diabetes Mellitus, Type 1, Type 1 Diabetes Mellitus | Phase 1 | Completed | Stanford University | 10 | 2025-10-28 | 2026-07-08 |
| Clinical Study to Evaluate the Pharmacokinetics and Safety of CKD-383 0.5/10/1000mg in Healthy Volunteers CKD-383 0.5/10/1000mg, CKD-501, D744, D150 - Type 2 Diabetes | Phase 1 | Completed | Chong Kun Dang Pharmaceutical | 30 | 2025-10-28 | 2025-12-26 |
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Diabetes Mellitus, Type 2 (890) · Diabetes Mellitus (569) · Pancreatic Neoplasms (468) · Ovarian Neoplasms (461) · Diabetes Mellitus, Type 1 (306) · Breast Neoplasms (219) · Carcinoma, Non-Small-Cell Lung (164) · Carcinoma, Ovarian Epithelial (152) · Colorectal Neoplasms (152) · Fallopian Tube Neoplasms (137) · Neoplasms (136) · Stomach Neoplasms (112) · Lung Neoplasms (95) · Prostatic Neoplasms (86) · Colonic Neoplasms (85)
Nutritional and Metabolic Diseases (1530) · Metabolic Diseases (1510) · Glucose Metabolism Disorders (1493) · Diabetes Mellitus (1013) · Neoplasms by Site (995) · Endocrine Gland Neoplasms (989) · Neoplasms (899) · Urogenital Diseases (692) · Female Urogenital Diseases and Pregnancy Complications (678) · Female Urogenital Diseases (674) · Digestive System Diseases (621) · Gonadal Disorders (615) · Genital Diseases (600) · Digestive System Neoplasms (595)
Gemcitabine (161) · Metformin (113) · Carboplatin (80) · Paclitaxel (73) · Insulin Glargine (57) · Insulin Aspart (56) · semaglutide (55) · Albumin-Bound Paclitaxel (52) · 130-nm albumin-bound paclitaxel (50) · Insulin Lispro (45) · insulin degludec (45) · Liraglutide (42) · Sitagliptin Phosphate (40) · Oxaliplatin (36) · Capecitabine (35)
Novo Nordisk A/S (265) · Eli Lilly and Company (107) · AstraZeneca (95) · National Cancer Institute (NCI) (74) · Merck Sharp & Dohme LLC (60) · GlaxoSmithKline (56) · Pfizer (52) · Sanofi (42) · Chong Kun Dang Pharmaceutical (36) · Memorial Sloan Kettering Cancer Center (31) · Boehringer Ingelheim (25) · Jiangsu HengRui Medicine Co., Ltd. (23) · Bayer (20) · Hoffmann-La Roche (20) · M.D. Anderson Cancer Center (20)
United States (1416) · Germany (330) · China (180) · United Kingdom (137) · South Korea (121) · Canada (109) · Japan (81) · Spain (78) · Australia (65) · France (64) · Netherlands (61) · Belgium (58) · Denmark (48) · Austria (40) · Italy (33)
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