8 completed, 1 not yet recruiting. 9 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 9 | Completed 8, Not yet recruiting 1 |
| Phase 2 | 1 | Completed 1 |
Follow Dupuytren's Contracture: new trials by email Literature Review of Dupuytren's Contracture trials Research Report on Dupuytren's Contracture
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| DEPART Study at Yale Radiation Therapy - Dupuytren's Contracture | Phase 3 | Not yet recruiting | Yale University | 158 | 2026-11-01 | 2026-10-13 |
| Safety and Efficacy of Two Concurrent Injections of AA4500 in Adult Subjects With Multiple Dupuytren's Contractures XIAFLEX / XIAPEX - Dupuytren's Contracture | Phase 3 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 715 | 2012-09-01 | 2017-10-05 |
| Collagenase Option for Reduction of Dupuytren's Contracture in Japan Collagenase Clostridium Histolyticum - Dupuytren's Contracture | Phase 3 | Completed | Asahi Kasei Therapeutics Corporation | 104 | 2012-05-01 | 2017-03-21 |
| Administration of Two Injections for Multiple Dupuytren's Contractures AA4500 collagenase clostridium histolyticum - Dupuytren's Contracture | Phase 3 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 60 | 2011-09-01 | 2017-10-05 |
| Treatment Of Dupuytren's Contracture With Collagenase Clostridium Histolyticum Injection (Xiapex) Xiapex - Dupuytren's Contracture | Phase 3 | Completed | Pfizer | 254 | 2010-12-01 | 2014-03-17 |
| Effects of Steroid Injection With Percutaneous Needle Aponeurotomy in Dupuytren's Contracture Triamcinolone Acetonide - Dupuytren's Contracture | Phase 3 | Completed | Sunnybrook Health Sciences Centre | 51 | 2007-11-01 | 2013-12-13 |
| Evaluation of the Efficiency of Autologous Platelet Gel (Platelet Rich Fibrin) Obtained From Own Patients' Blood Versus Vaselitulle in Dupuytren's Disease Postoperative Wound Healing Autologous platelets gel, Vaselitulle - Dupuytren's Contracture | Phase 2 / Phase 3 | Completed | Centre Hospitalier Universitaire de Nice | 80 | 2007-08-01 | 2012-03-20 |
| AA4500 (XIAFLEX™, Proposed Name) in the Treatment of Dupuytren's Contracture collagenase clostridium histolyticum, Placebo - Dupuytren's Contracture | Phase 3 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 308 | 2007-08-01 | 2017-12-02 |
| Phase III Randomized Study of Collagenase in Patients With Residual Stage Dupuytren's Disease collagenase - Dupuytren's Contracture | Phase 3 | Completed | State University of New York | 72 | 2015-03-25 |
Dupuytren Contracture (9) · Arthritis (1) · Connective Tissue Diseases (1) · Contracture (1) · Rare Diseases (1)
Fibroma (9) · Muscular Diseases (9) · Musculoskeletal Diseases (9) · Neoplasms (9) · Neoplasms by Histologic Type (9) · Neoplasms, Connective Tissue (9) · Neoplasms, Connective and Soft Tissue (9) · Neoplasms, Fibrous Tissue (9) · Skin and Connective Tissue Diseases (9) · Connective Tissue Diseases (8) · Contracture (8) · Joint Diseases (2) · Disease Attributes (1) · Pathologic Processes (1) · Pathological Conditions, Signs and Symptoms (1)
Microbial Collagenase (4) · xiapex (4) · Collagenases (1) · Radiotherapy (1) · Triamcinolone Acetonide (1)
Endo USA Inc., a Keenova Therapeutics Company (3) · Asahi Kasei Therapeutics Corporation (1) · Centre Hospitalier Universitaire de Nice (1) · Pfizer (1) · State University of New York (1) · Sunnybrook Health Sciences Centre (1) · Yale University (1)
United States (4) · France (2) · Australia (1) · Canada (1) · Denmark (1) · Germany (1) · Hungary (1) · Italy (1) · Japan (1) · Spain (1) · Sweden (1) · United Kingdom (1)
Veronica Urdaneta, MD, MPPH (2) · Bruce McGibbon, MD (1) · Frank D Buono, PhD (1) · Lawrence C. Hurst (1) · Paul A. Binhammer, MD,MSc (1) · Veronica Urdaneta, MD (1)
PMID 19726771, PMID 21967070, PMID 23190833, PMID 24470559, PMID 27313184