7 terminated. 7 Phase 2, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Terminated 7 |
| Phase 3 | 3 | Terminated 3 |
Follow Drug Resistant Epilepsy: new trials by email Literature Review of Drug Resistant Epilepsy trials Research Report on Drug Resistant Epilepsy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Determine if BHV-7000 is Effective and Safe in Adults With Idiopathic Generalized Epilepsy With Generalized Tonic-clonic Seizures BHV-7000, Placebo - Generalized Epilepsy | Phase 2 / Phase 3 | Terminated | Biohaven Therapeutics Ltd. | 27 | 2024-06-20 | 2026-03-24 |
| A Study to Evaluate Efficacy and Safety of Vatiquinone for Treating Mitochondrial Disease in Participants With Refractory Epilepsy Vatiquinone, Placebo - Mitochondrial Diseases, Drug Resistant Epilepsy | Phase 2 / Phase 3 | Terminated | PTC Therapeutics | 68 | 2020-09-28 | 2026-03-31 |
| Study to Assess Intracerebroventricular (ICV) Delivery of CT-010 in Subjects With Focal Seizures, With Temporal Lobe Onset With or Without Secondary Generalization ICV delivery of CT-010 via an implantable pump and a cranial port and dual lumen catheter (CIC), Placebo delivery via an implantable pump and a cranial port and dual lumen catheter (CIC) - Refractory Epilepsy | Phase 2 | Terminated | Cerebral Therapeutics LLC | 30 | 2020-08-21 | 2024-03-13 |
| Study to Test the Safety and Efficacy of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy Padsevonil - Drug-Resistant Epilepsy, Focal-Onset Seizures | Phase 2 | Terminated | UCB Biopharma SRL | 406 | 2018-08-27 | 2021-12-29 |
| Bioavailability, Safety and Tolerability of Diazepam Nasal Spray Versus Diazepam Rectal Gel (Diastat®) diazepam nasal spray, diazepam rectal gel - Refractory Epilepsy | Phase 2 | Terminated | Acorda Therapeutics | 78 | 2015-06-01 | 2018-10-16 |
| IVIG Treatment for Refractory Immune-Related Adult Epilepsy IVIG - Epilepsy, Cryptogenic, Epilepsy, Partial | Phase 2 | Terminated | Emory University | 20 | 2011-11-01 | 2014-09-01 |
| STIMEP : Assessment of Subthalamic Nucleus Stimulation in Drug Resistant Epilepsy Neurostimulation - Epilepsy, Drug Resistant | Phase 2 / Phase 3 | Terminated | University Hospital, Grenoble | 4 | 2005-09-01 | 2015-05-28 |
Epilepsy (4) · Seizures (4) · Autoimmune Diseases (1) · Autoimmune Diseases of the Nervous System (1) · Diffuse Cerebral Sclerosis of Schilder (1) · Epilepsies, Partial (1) · Epilepsy, Absence (1) · Epilepsy, Generalized (1) · Epilepsy, Idiopathic Generalized (1) · Leigh Disease (1) · Limbic Encephalitis (1) · MELAS Syndrome (1) · MERRF Syndrome (1) · Mitochondrial Diseases (1)
Brain Diseases (7) · Central Nervous System Diseases (7) · Nervous System Diseases (7) · Neurologic Manifestations (4) · Pathological Conditions, Signs and Symptoms (4) · Signs and Symptoms (4) · Epilepsy (3) · Epilepsies, Myoclonic (2) · Epileptic Syndromes (2) · Immune System Diseases (2) · Autoimmune Diseases (1) · Autoimmune Diseases of the Nervous System (1) · Brain Diseases, Metabolic (1) · Brain Diseases, Metabolic, Inborn (1) · Carbohydrate Metabolism, Inborn Errors (1)
Diazepam (1) · Immunoglobulins, Intravenous (1) · alpha-tocotrienol quinone (1) · padsevonil (1)
Acorda Therapeutics (1) · Biohaven Therapeutics Ltd. (1) · Cerebral Therapeutics LLC (1) · Emory University (1) · PTC Therapeutics (1) · UCB Biopharma SRL (1) · University Hospital, Grenoble (1)
United States (5) · France (4) · Australia (3) · Italy (3) · Poland (3) · Spain (3) · United Kingdom (3) · Belgium (2) · Canada (2) · Croatia (2) · Finland (2) · Germany (2) · Japan (2) · Austria (1) · Bosnia and Herzegovina (1)
Charles M. Epstein, M.D. (1) · Lee Min Jae (1) · Vinay Penematsa, MD (1)
2017 (1), 2023 (1)