1 completed, 1 terminated, 1 unknown. 3 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 3 | Completed 1, Terminated 1, Unknown 1 |
| Phase 2 | 1 | Terminated 1 |
Follow Diffuse Cerebral Sclerosis of Schilder: new trials by email Literature Review of Diffuse Cerebral Sclerosis of Schilder trials Research Report on Diffuse Cerebral Sclerosis of Schilder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Safety Study for Previously Treated Vatiquinone (PTC743) Participants With Inherited Mitochondrial Disease Vatiquinone - Inherited Mitochondrial Disease | Phase 3 | Completed | PTC Therapeutics | 101 | 2022-06-22 | 2025-12-22 |
| A Study to Evaluate Efficacy and Safety of Vatiquinone for Treating Mitochondrial Disease in Participants With Refractory Epilepsy Vatiquinone, Placebo - Mitochondrial Diseases, Drug Resistant Epilepsy | Phase 2 / Phase 3 | Terminated | PTC Therapeutics | 68 | 2020-09-28 | 2026-03-31 |
| Phase III Randomized, Double-Blind, Sham-Controlled Study of Plasma Exchange for Acute Severe Attacks of Inflammatory Demyelinating Disease Refractory to Intravenous Methylprednisolone Plasma exchange - Acute Disseminated Encephalomyelitis, Devic's Syndrome | Phase 3 | Unknown | National Institute of Neurological Disorders and Stroke (NINDS) | 22 | 1995-01-01 | 2005-06-24 |
Drug Resistant Epilepsy (2) · Leigh Disease (2) · MELAS Syndrome (2) · MERRF Syndrome (2) · Encephalomyelitis, Acute Disseminated (1) · Mental Disorders (1) · Mitochondrial Diseases (1) · Mitochondrial Encephalomyopathies (1) · Mitochondrial encephalopathy (1) · Multiple Sclerosis (1) · Myelitis, Transverse (1) · Nerve Degeneration (1) · Neurologic Manifestations (1) · Neuromyelitis Optica (1)
Autoimmune Diseases (3) · Autoimmune Diseases of the Nervous System (3) · Brain Diseases (3) · Central Nervous System Diseases (3) · Demyelinating Autoimmune Diseases, CNS (3) · Demyelinating Diseases (3) · Immune System Diseases (3) · Leukoencephalopathies (3) · Nervous System Diseases (3) · Brain Diseases, Metabolic (2) · Brain Diseases, Metabolic, Inborn (2) · Carbohydrate Metabolism, Inborn Errors (2) · Cardiovascular Diseases (2) · Cerebral Small Vessel Diseases (2) · Cerebrovascular Disorders (2)
alpha-tocotrienol quinone (2) · Plasma Exchange (1)
PTC Therapeutics (2) · National Institute of Neurological Disorders and Stroke (NINDS) (1)
France (2) · Italy (2) · Japan (2) · Poland (2) · Spain (2) · United Kingdom (2) · United States (2) · Canada (1) · Sweden (1)
Vinay Penematsa, MD (2) · Brian G. Weinshenker (1)