19 completed. 19 Phase 3, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 19 | Completed 19 |
| Phase 2 | 5 | Completed 5 |
Follow Diabetes, Gestational: new trials by email Literature Review of Diabetes, Gestational trials Research Report on Diabetes, Gestational
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Inhaled Insulin vs Rapid-acting Injections for Post-meal Glucose Control in Women With Gestational Diabetes Inhaled Technosphere Insulin - Diabetes, Gestational, Pregnancy Complications | Phase 2 / Phase 3 | Completed | Jaeb Center for Health Research | 30 | 2025-06-02 | 2026-10-19 |
| A Pragmatic Approach to Lower Diabetes Risk After Gestational Diabetes Metformin - Diabetes, Gestational, PreDiabetes | Phase 3 | Completed | Tufts Medical Center | 20 | 2022-06-01 | 2025-04-20 |
| Gestational Treatment With Ursodeoxycholic Acid Compared to Placebo to Reduce Severity of Gestational Diabetes Mellitus Diagnosed at 24-28 Weeks' Gestation 500 mg of ursodeoxycholic acid (UDCA), 500 mg of Placebo - Gestational Diabetes | Phase 3 | Completed | Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia | 113 | 2021-03-03 | 2023-11-14 |
| Empagliflozin and the Preservation of Beta-cell Function in Women with Recent Gestational Diabetes Empagliflozin 10 MG, Placebo oral capsule - Gestational Diabetes | Phase 3 | Completed | Mount Sinai Hospital, Canada | 91 | 2018-07-01 | 2025-03-07 |
| Maternal Weight Gain in Gestational Diabetes Controlled by Metformin Versus Insulin Insulin, Metformin, Assessment of weight gain - Gestational Diabetes | Phase 3 | Completed | Ain Shams University | 124 | 2018-02-01 | 2019-02-15 |
| RCT Metformin for Reduction of Gestational Diabetes Mellitus Effects Metformin Hydrochloride, Placebo - Gestational Diabetes | Phase 3 | Completed | National University of Ireland, Galway, Ireland | 535 | 2017-06-06 | 2025-03-17 |
| Dextrose Gel Does Not Prevent Neonatal Hypoglycemia 40% Dextrose gel - Hypoglycemia, Infant, Small for Gestational Age | Phase 2 / Phase 3 | Completed | Baylor College of Medicine | 236 | 2016-07-01 | 2025-01-08 |
| Comparison of Metformin and Insulin for Management of Gestational Diabetes Mellitus Metformin, Insulin - Gestational Diabetes Mellitus in Pregnancy | Phase 3 | Completed | Services Institute of Medical Sciences, Pakistan | 278 | 2016-02-01 | 2017-10-27 |
| Medico-GDM Trial - Metformine to Prevent Gestational Diabetes Mellitus Metformin, control diet - Gestational Diabetes Mellitus | Phase 3 | Completed | Maasstad Hospital | 400 | 2014-10-08 | 2026-10-09 |
| A Feasibility Study Looking at the Use of Glibenclamide and metfoRmin Versus stAndard Care in gEstational diabeteS Glibenclamide, Insulin - Pregnancy, Gestational Diabetes | Phase 3 | Completed | University of Edinburgh | 23 | 2014-07-01 | 2016-12-08 |
| Multicenter Randomized Trial of Non-inferiority Between Glyburide and Insulin for the Treatment of Gestational Diabetes Insulin, Glyburide - Diabetes, Gestational | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 914 | 2012-05-18 | 2025-09-05 |
| MAIN STUDY: Low Glycaemic Index (GI) Diet in the Management of GDM SUB-STUDY: The Breast Milk Sub-Study Standard Care, Low GI diet - Gestational Diabetes Mellitus | Phase 2 / Phase 3 | Completed | University of Toronto | 99 | 2011-10-01 | 2016-05-20 |
| Combined Liraglutide and Metformin Therapy in Women With Previous Gestational Diabetes Mellitus (GDM) Metformin XR plus placebo, Metformin XR plus liraglutide - Gestational Diabetes Mellitus, Type 2 Diabetes Mellitus | Phase 3 | Completed | Woman's | 153 | 2011-08-11 | 2019-07-26 |
| Metformin in Obese Non-diabetic Pregnant Women Metformin, Placebo - Pregnancy Complications, Obesity | Phase 2 / Phase 3 | Completed | Epsom and St Helier University Hospitals NHS Trust | 450 | 2010-10-01 | 2016-01-22 |
| Gestational Diabetes: Insulin or Oral Hypoglycemic Agents? Insulin, Metformin, glyburide and insulin - Gestational Diabetes Mellitus | Phase 3 | Completed | Université de Sherbrooke | 73 | 2010-08-01 | 2018-05-03 |
| Efficacy of Behavioral Therapy and Exercise in Gestational Diabetes Mellitus (GDM) Behavioral therapy, Exercise, Behavioral therapy and exercise - Birth-weight | Phase 3 | Completed | University of Turin, Italy | 200 | 2009-07-01 | 2013-01-23 |
| Metformin Versus Insulin in the Treatment of Gestational Diabetes Mellitus Metformin, Insulin - Gestational Diabetes Mellitus | Phase 2 / Phase 3 | Completed | University of Oulu | 97 | 2005-06-01 | 2010-03-16 |
| The Effects of Metformin on Pregnancy and Miscarriage Rates in Polycystic Ovary Syndrome (PCOS) metformin - Polycystic Ovary Syndrome, Miscarriage | Phase 3 | Completed | University of Oulu | 326 | 2002-08-01 | 2010-02-23 |
| Safety and Efficacy of Insulin Aspart vs. Regular Human Insulin in Gestational Diabetes human insulin, insulin NPH, insulin aspart - Diabetes, Gestational Diabetes | Phase 3 | Completed | Novo Nordisk A/S | 27 | 2000-04-01 | 2016-12-22 |
Diabetes Mellitus (4) · Insulin Resistance (4) · Pregnancy Complications (3) · Diabetes Mellitus, Type 2 (2) · Abortion, Spontaneous (1) · Birth Weight (1) · Fetal Growth Retardation (1) · Fetal Macrosomia (1) · Glucose Intolerance (1) · Glucose Metabolism Disorders (1) · Hyperglycemia (1) · Hypoglycemia (1) · Infertility (1) · Metabolic Syndrome (1)
Endocrine System Diseases (19) · Female Urogenital Diseases and Pregnancy Complications (19) · Metabolic Diseases (19) · Nutritional and Metabolic Diseases (19) · Urogenital Diseases (19) · Glucose Metabolism Disorders (18) · Pregnancy Complications (16) · Diabetes Mellitus (15) · Hyperinsulinism (5) · Body Weight (3) · Pathological Conditions, Signs and Symptoms (3) · Signs and Symptoms (3) · Adnexal Diseases (1) · Birth Weight (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1)
Metformin (9) · Insulin (7) · Glyburide (3) · Behavior Therapy (1) · Exercise (1) · Glycemic Index (1) · Insulin Aspart (1) · Insulin, Isophane (1) · Isophane Insulin, Human (1) · Liraglutide (1) · Standard of Care (1) · Ursodeoxycholic Acid (1) · empagliflozin (1)
University of Oulu (2) · Ain Shams University (1) · Assistance Publique - Hôpitaux de Paris (1) · Baylor College of Medicine (1) · Epsom and St Helier University Hospitals NHS Trust (1) · Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia (1) · Jaeb Center for Health Research (1) · Maasstad Hospital (1) · Mount Sinai Hospital, Canada (1) · National University of Ireland, Galway, Ireland (1) · Novo Nordisk A/S (1) · Services Institute of Medical Sciences, Pakistan (1) · Tufts Medical Center (1) · University of Edinburgh (1) · University of Toronto (1)
United States (5) · Canada (3) · Finland (2) · United Kingdom (2) · Egypt (1) · France (1) · Ireland (1) · Italy (1) · Netherlands (1) · Pakistan (1) · Spain (1)
Amy Valent, DO (1) · Dr Jyoti Balani, MD (1) · Dr Ranjit Akolekar (1) · Dr Steve Hyer, MD, FRCP (1) · Erika Werner, MD (1) · Hilkka Ijas, MD (1) · Jane E Norman, MD (1) · Jean-Luc Ardilouze, MD, PhD (1) · Jeffrey R Kaiser, MD, MA, FAAP (1) · Joke van der Linden, dr. (1) · Karen E Elkind-Hirsch, Ph.D. (1) · Laure C Morin-Papunen, PhD (1)
PMID 12502678, PMID 17888133, PMID 21083860, PMID 23122829, PMID 25646328, PMID 26840133, PMID 28938877, PMID 29605395, PMID 29715355, PMID 31227287, PMID 32046931, PMID 36131291, PMID 37786390, PMID 39215812, PMID 40964955
2008 (1), 2014 (1)