8 completed, 3 not yet recruiting, 2 withdrawn, 1 recruiting. 8 Not applicable, 3 Phase 4, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 8 | Completed 5, Not yet recruiting 2, Recruiting 1 |
| Phase 4 | 3 | Completed 2, Withdrawn 1 |
| Phase 2 | 2 | Not yet recruiting 1, Withdrawn 1 |
Follow Dental Anesthesia: new trials by email Literature Review of Dental Anesthesia trials Research Report on Dental Anesthesia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| MRI and Local Anesthesia ddMRI - Dental Anesthesia | Not applicable | Not yet recruiting | University of Minnesota | 102 | 2026-12-15 | 2026-09-10 |
| Melissa Officinalis Aromatherapy for Dental Anxiety in Children Aromatherapy with Melissa officinalis essential oil - Brand A, Aromatherapy with Melissa officinalis essential oil - Brand B, Standard behavioral management - Emotional Anxiety and Stress During Pediatric Dental Treatment, Dental Anesthesia | Phase 2 | Not yet recruiting | Universidad Autonoma de San Luis Potosí | 45 | 2026-06-15 | 2026-05-18 |
| Survey on Knowledge and Acceptance of Dental General Anesthesia for Children Among Different Populations Questionnaire-based survey - Pediatric Dentistry, Dental Anesthesia | Completed | Air Force Military Medical University, China | 1490 | 2026-02-01 | 2026-06-03 | |
| Efficacy of Pre-cooling and Sweet-tasting Solution on Pain Related to Local Anesthesia Injection in Children Dental anesthesia - Dental Anesthesia, Sweet Taste Perception | Not applicable | Recruiting | British University In Egypt | 224 | 2025-10-06 | 2026-09-22 |
| Effect of Cold Atmospheric Plasma on Patient Comfort During Dental Anesthesia Cold Atmospheric Plasma, No pretreatment - Cold Atmospheric Plasma, Dental Anesthesia | Not applicable | Completed | Kahramanmaras Sutcu Imam University | 30 | 2025-09-01 | 2025-12-23 |
| "Study of Pain Perception Using Computer-Controlled Versus Conventional Local Anaesthesia in Children Undergoing Molar Extraction A conventional dental syringe, GENI High-Speed Injection, GENI Moderate-Speed Injection - Dental Phobia, Dental Anxiety | Not applicable | Not yet recruiting | Tarek MHD kher al saka amini | 76 | 2025-07-01 | 2025-07-14 |
| Clinical Evaluation and Comparison of Pain Acceptance of Different Types of Injection Systems Comfort-In, Traditional dental injection - Dental Anesthesia | Not applicable | Completed | Necmettin Erbakan University | 76 | 2024-01-22 | 2025-03-25 |
| Effect of Pre-Warming of Local Anesthesia in Reducing Pain Perception During Injection in Children Local anesthesia solution at room temperature, Local anesthesia solution pre-warmed to 37°C, Local anesthesia solution pre-warmed to 40°C - Local Anesthesia, Dental Anesthesia | Not applicable | Completed | Andrew Emad | 72 | 2024-01-01 | 2024-07-25 |
| Effect of Subperiosteal Ropivacaine After Third Molar Extraction Ropivacaine 0.75%, Saline (0.9% NaCl) - Wisdom Tooth Removal, Dental Anesthesia | Phase 4 | Completed | University of Zagreb | 30 | 2023-10-02 | 2026-09-28 |
| Digital vs. Conventional Anesthesia for Primary Tooth Extractions in Pediatric Patients SleeperOne™, Conventional Infiltration Anesthesia - Pain Management, Dental Anxiety | Not applicable | Completed | Ege University | 20 | 2020-01-20 | 2025-07-25 |
| Efficacy of Tetracaine/Oxymetazoline Nasal Spray for Endodontic Treatment Tetracaine HCl and oxymetazoline HCl nasal spray - Endodontic Disease, Endodontic Inflammation | Phase 4 | Withdrawn | University of North Carolina, Chapel Hill | 2018-09-01 | 2018-11-16 | |
| Is the Direct Inferior Alveolar Nerve Block Required for Third Lower Molar Extraction? Nerve block technique, Infiltrative technique, 4% articaine 1:100.000 epinephrine - Tooth Extraction, Dental Anesthesia | Not applicable | Completed | University of Barcelona | 120 | 2017-06-10 | 2020-03-31 |
| Hemodynamic and Pharmacokinetic Analysis of Oxymetazoline Absorption Oxymetazoline - Dental Anesthesia, Nasal Surgical Procedures | Phase 2 | Withdrawn | Richard Cartabuke | 2014-06-01 | 2015-08-07 | |
| Study of OraVerse® for Safety and Efficacy in Pediatric Dental Patients OraVerse, Sham injection - Dental Anesthesia, Anesthesia, Local | Phase 4 | Completed | Novocol Pharmaceutical of Canada, Inc. | 150 | 2012-02-01 | 2014-08-29 |
Agnosia (1) · Anxiety Disorders (1) · Behavior (1) · Dental Pulp Diseases (1) · Pain (1) · Pulpitis (1)
Neurologic Manifestations (2) · Pathological Conditions, Signs and Symptoms (2) · Signs and Symptoms (2) · Mental Disorders (1) · Nervous System Diseases (1) · Neurobehavioral Manifestations (1) · Perceptual Disorders (1) · Stomatognathic Diseases (1) · Tooth Diseases (1)
Anesthesia, Dental (1) · Aromatherapy (1) · Carticaine (1) · Epinephrine (1) · Oxymetazoline (1) · Phentolamine (1) · Plasma Gases (1) · Sodium Chloride (1) · Tetracaine (1) · salicylhydroxamic acid (1)
Air Force Military Medical University, China (1) · Andrew Emad (1) · British University In Egypt (1) · Ege University (1) · Kahramanmaras Sutcu Imam University (1) · Necmettin Erbakan University (1) · Novocol Pharmaceutical of Canada, Inc. (1) · Richard Cartabuke (1) · Tarek MHD kher al saka amini (1) · Universidad Autonoma de San Luis Potosí (1) · University of Barcelona (1) · University of Minnesota (1) · University of North Carolina, Chapel Hill (1) · University of Zagreb (1)
Egypt (3) · Turkey (Türkiye) (3) · United States (3) · China (1) · Croatia (1) · Spain (1)
Adam Marberger, DDS (1) · Asma Khan, DDS (1) · Brent Lin, DMD (1) · Davor Brajdic, DMD, PhD (1) · Eduard Valmaseda-Castellon, DDS, MS. PhD (1) · Elliot Hersh, DMD,MS,PhD (1) · Halenur Altan (1) · Joel Berg, DDS,MS (1) · Judith Chin, DDS,MS (1) · Leonardo Berini-Aytes, MD, DDS, PhD (1) · Octavi Camps-Font, DDS, MS (1) · Paul Casamassimo, MS,DDS (1) · Paul Moore, DMD,PhD,MPH (1) · Rachel Uppgaard, DDS, FACS (1)