4 completed, 3 unknown, 2 active not recruiting, 1 recruiting. 11 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 11 | Completed 4, Unknown 3, Active not recruiting 2, Recruiting 1, Terminated 1 |
Follow Contracture: new trials by email Literature Review of Contracture trials Research Report on Contracture
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Efficacy of Liposomal Bupivacaine in Ultrasound Guided Supraclavicular Nerve Blocks for Hand and Wrist Surgery Liposomal bupivacaine (LB), Dexamethasone - Hand Surgery, Wrist Surgery | Phase 4 | Active not recruiting | St. Luke's Hospital, Pennsylvania | 120 | 2023-05-01 | 2025-02-06 |
| Percutaneous Needle Fasciotomy +/- Corticosteroid Injection for Dupuytren's Contracture Percutaneous needle fasciotomy, Corticosteroid injection, Saline injection - Dupuytren Contracture, Dupuytren's Disease | Phase 4 | Recruiting | Regionshospitalet Silkeborg | 400 | 2023-01-10 | 2023-05-17 |
| The Role of Tranexamic Acid in Reducing Post Operative Hand Edema After Hand and Wrist Surgery Tranexamic acid, Surgery - Hand Injuries and Disorders, Distal Radius Fracture | Phase 4 | Unknown | Ruby Grewal | 50 | 2021-06-01 | 2021-06-01 |
| Trial Comparing Treatment Strategies in Dupuytren's Contracture Percutaneous needle fasciotomy (PNF), Collagenase Clostridium Histolyticum (CCH) 2.9 MG/ML [Xiaflex], Limited fasciectomy (LF) - Dupuytren Contracture | Phase 4 | Active not recruiting | Tampere University | 302 | 2017-09-15 | 2026-04-29 |
| Collagenase Injection vs Percutaneous Needle Aponeurotomy for Dupuytren's Disease Percutaneous Needle Aponeurotomy, XIAFLEX - Dupuytren Contracture, Dupuytren's Disease of Finger | Phase 4 | Unknown | University of Calgary | 334 | 2016-01-01 | 2016-12-21 |
| Prospective Randomized Trial Between Needle Fasciotomy and Xiapex for Dupuytrens Contracture xiapex, percutaneous needle fasciotomy - Dupuytrens Contracture | Phase 4 | Unknown | Oslo University Hospital | 50 | 2015-04-01 | 2015-06-19 |
| Dupuytren´s Disease Study. Primary Disease, MCP Joint, Xiapex, PNF Xiapex, Needle aponeurotomy - Dupuytren Contracture | Phase 4 | Completed | University Hospital, Akershus | 80 | 2013-10-01 | 2022-04-26 |
| Retreatment of Recurrent Dupuytren's Contractures Collagenase clostridium histolyticum - Dupuytren's Disease | Phase 4 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 52 | 2012-03-01 | 2017-10-05 |
| MRI Results in Dupuytren's Contracture Before and After Injection With Xiaflex XIAFLEX - Dupuytren's Disease | Phase 4 | Completed | Hospital for Special Surgery, New York | 5 | 2011-03-01 | 2017-04-17 |
| Efficacy and Safety of Xiaflex Injection for Treatment of Dupuytren's Contracture of the Thumb Injectable clostridial collagenase - Dupuytren's Contracture | Phase 4 | Completed | Indiana Hand to Shoulder Center | 7 | 2010-12-01 | 2015-04-30 |
| Safety and Efficacy of Delayed Manipulation After Xiaflex Treatment in Subjects With Dupuytren's Contracture Clostridial collagenase injectable - Dupuytren's Disease | Phase 4 | Terminated | Indiana Hand to Shoulder Center | 37 | 2010-12-01 | 2014-06-16 |
Dupuytren Contracture (11) · Connective Tissue Diseases (2) · Wrist Fractures (2) · Disease (1) · Edema (1) · Fibroma (1) · Hand Injuries (1) · Joint Diseases (1) · Musculoskeletal Diseases (1) · Neoplasms (1) · Neoplasms by Histologic Type (1) · Neoplasms, Connective Tissue (1) · Neoplasms, Connective and Soft Tissue (1) · Neoplasms, Fibrous Tissue (1)
Muscular Diseases (11) · Skin and Connective Tissue Diseases (11) · Fibroma (10) · Musculoskeletal Diseases (10) · Neoplasms (10) · Neoplasms by Histologic Type (10) · Neoplasms, Connective Tissue (10) · Neoplasms, Connective and Soft Tissue (10) · Neoplasms, Fibrous Tissue (10) · Connective Tissue Diseases (9) · Arm Injuries (2) · Fractures, Bone (2) · Joint Diseases (2) · Wounds and Injuries (2)
Microbial Collagenase (6) · xiapex (4) · Adrenal Cortex Hormones (1) · Collagenases (1) · Dexamethasone (1) · Sodium Chloride (1) · Surgical Procedures, Operative (1) · Tranexamic Acid (1)
Indiana Hand to Shoulder Center (2) · Endo USA Inc., a Keenova Therapeutics Company (1) · Hospital for Special Surgery, New York (1) · Oslo University Hospital (1) · Regionshospitalet Silkeborg (1) · Ruby Grewal (1) · St. Luke's Hospital, Pennsylvania (1) · Tampere University (1) · University Hospital, Akershus (1) · University of Calgary (1)
United States (5) · Canada (2) · Norway (2) · Australia (1) · Denmark (1) · Finland (1) · Sweden (1) · United Kingdom (1)
Aleksi RP Reito, M.D., Ph.D., adjunct professor (1) · Anna Ng-Pellegrino, MD (1) · Antti OV Malmivaara, M.D., Ph.D., adjunct professor (1) · F. Thomas D. Kaplan, MD (1) · Hannu Kautiainen, MSc (1) · Jeppe Lange, MD, PhD (1) · Justin Yeung, MD (1) · Lawrence C Hurst, MD (1) · Per-Henrik Randsborg, PhD (1) · Scott W Wolfe, MD (1) · Veronica Urdaneta, MD, MPPH (1)