44 completed. 44 Phase 2, 6 Phase 1, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 44 | Completed 44 |
| Phase 1 | 6 | Completed 6 |
| Phase 3 | 3 | Completed 3 |
Follow Contraception: new trials by email Literature Review of Contraception trials Research Report on Contraception
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dose-finding Study of MR-130A-01 Contraceptive Transdermal Patch MR-130A-01 Transdermal patch - Contraception | Phase 2 | Completed | Mylan Pharmaceuticals Inc | 168 | 2023-12-22 | 2024-11-29 |
| The PRICE Trial: Pain Reduction for Intrauterine Contraception Experiment 1% Lidocaine Paracervical Block, Normal Saline Paracervical Injection - Contraception | Phase 2 | Completed | Mount Sinai Hospital, Canada | 246 | 2022-06-30 | 2025-01-27 |
| Pharmacologic Strategies for the Etonogestrel Implant in HIV-Infected Women etonogestrel implant - HIV/AIDS, Contraception | Phase 2 | Completed | Catherine Anne Chappell | 72 | 2019-02-19 | 2024-09-05 |
| Effect of Norgestrel 75 mcg on Cervical Mucus and Ovarian Activity During Perfect Use, After One Delayed Intake and After a Missed Pill Norgestrel 0.075 mg - Contraception | Phase 2 | Completed | HRA Pharma | 52 | 2018-07-24 | 2021-06-03 |
| A Study to Compare 3 Doses of a Hormonal Intra-uterine Device Containing Levonorgestrel and Indomethacin With a Hormonal Intra-uterine Device Containing Only Levonorgestrel to Assess the Effect and Safety of the Combined Components BAY98-7443, Levonogestrel (Skyla, BAY86-5028) - Contraception | Phase 2 | Completed | Bayer | 177 | 2018-06-22 | 2019-08-12 |
| Pharmacologic Strategies to Use the Levonorgestrel Implant in HIV-infected Women Levonorgestrel, Efavirenz - HIV, Contraception | Phase 2 | Completed | University of Nebraska | 28 | 2017-04-06 | 2024-10-03 |
| Evaluation of the Efficacy and Safety of LevoCept LevoCept - Contraception | Phase 2 | Completed | Sebela Women's Health Inc. | 279 | 2016-11-01 | 2026-04-23 |
| "E4/DRSP Endocrine Function, Metabolic Control and Hemostasis Study" 15 mg E4/3 mg DRSP, 30 mcg EE/150 mcg LNG, 20 mcg EE/3 mg DRSP - Contraception, Liver Metabolism | Phase 1 / Phase 2 | Completed | Estetra | 101 | 2016-09-01 | 2018-02-05 |
| Evaluation of a Novel and Simplified Technique for Intrauterine Contraceptive Devices Insertion: a Prospective Cohort Study IUD, Uterine sounding, Transvaginal ultrasound - Contraception | Phase 2 | Completed | Assiut University | 90 | 2016-01-01 | 2016-11-25 |
| The Effect of Ibuprofen on Intrauterine Contraceptive Device Associated Uterine Bleeding Ibuprofen - Contraception | Phase 2 | Completed | Assiut University | 128 | 2015-10-01 | 2017-03-21 |
| Russia/Ukraine Suppression of Ovarian Activity Study Gestodene/EE Patch (BAY86-5016) - Contraception | Phase 2 | Completed | Bayer | 91 | 2015-09-18 | 2017-08-07 |
| Evaluation of ContraMed VeraCept Intrauterine Copper Contraceptive for Long Acting Reversible Contraception VeraCept - Contraception | Phase 2 | Completed | Sebela Women's Health Inc. | 286 | 2015-06-01 | 2026-03-03 |
| A Pharmacokinetic Evaluation of Levonorgestrel Implant and Antiretroviral Therapy Levonorgestrel, Nevirapine, Efavirenz - HIV, Contraception | Phase 2 | Completed | University of Nebraska | 60 | 2014-03-04 | 2023-09-01 |
| Does Concomitant Use of Combined Oral Hormonal Steroids Stop Bleeding in Women Using Etonogestrel Implants (Implanon/Nexplanon®)?: A Randomized Controlled Study Combined Oral Contraceptive Pill, Placebo Sugar Pill - Uterine Hemorrhage, Contraception | Phase 2 | Completed | University of Colorado, Denver | 32 | 2013-10-01 | 2016-05-05 |
| Cilostazol and Its Effects on Resumption of Meiosis in the Human Ovary Cilostazol - Contraception | Phase 2 | Completed | University of Southern California | 4 | 2013-07-01 | 2015-05-12 |
| Safety and Acceptability of Vaginal Rings That Protect Women From Unintended Pregnancy Vaginal Ring - intermittent regimen, Vaginal Ring - continuous regimen - Contraception | Phase 2 / Phase 3 | Completed | Institute of Tropical Medicine, Belgium | 120 | 2013-06-01 | 2015-03-11 |
| A Dose-Finding Study to Evaluate Ovarian Function and Vaginal Bleeding in Next Generation Rings (P06109/MK-8175A/MK-8342B-012) Nomegestrol acetate (NOMAC), Etonogestrel (ENG), Ethinyl estradiol (EE) - Contraception | Phase 2 | Completed | Organon and Co | 666 | 2012-12-12 | 2024-05-28 |
| Smoking, Sex Hormones, and Pregnancy Low-dose Progesterone, High-dose Progesterone - Nicotine Dependence, Contraception | Phase 2 | Completed | University of Minnesota | 95 | 2012-12-01 | 2020-11-13 |
| A Multi-center, Open-label, Randomized, Parallel Group Study to Evaluate Pharmacokinetic Profile, Effects on the Mechanisms of Contraceptive Efficacy and Safety of Two Progestin-only Patches Containing Different Doses of Levonorgestrel (LNG) levonorgestrel patch with BMI 32 kg/m2 to <40 kg/m2, levonorgestrel patch with BMI <32 kg/m2 - Contraception | Phase 1 / Phase 2 | Completed | Premier Research | 121 | 2010-12-01 | 2026-01-07 |
| Cycle Control Assessment of a Combined Oral Contraceptive Containing Estetrol and a Progestin P1 or P2 estetrol, P 1 and placebo tablets, estetrol, P2 and placebo tablets, Estradiol valerate, dienogest and placebo tablets - Contraception | Phase 2 | Completed | Estetra | 396 | 2010-09-01 | 2012-09-14 |
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Acquired Immunodeficiency Syndrome (2) · Genital Diseases, Female (1) · HIV Infections (1) · Hypogonadism (1) · Tobacco Use Disorder (1) · Uterine Hemorrhage (1)
Genital Diseases (4) · Urogenital Diseases (4) · Blood-Borne Infections (2) · Communicable Diseases (2) · Female Urogenital Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Immune System Diseases (2) · Immunologic Deficiency Syndromes (2) · Infections (2) · Lentivirus Infections (2) · RNA Virus Infections (2) · Retroviridae Infections (2) · Sexually Transmitted Diseases (2) · Sexually Transmitted Diseases, Viral (2) · Slow Virus Diseases (2)
Ethinyl Estradiol (6) · Levonorgestrel (5) · Estradiol (3) · Medroxyprogesterone Acetate (3) · Testosterone (3) · etonogestrel (3) · ulipristal (3) · Dutasteride (2) · Efavirenz, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination (2) · Estetrol (2) · Gestodene (2) · N,N-dimethyl-4-anisidine (2) · acyline (2) · drospirenone (2) · efavirenz (2)
Bayer (10) · University of Washington (4) · HRA Pharma (3) · Organon and Co (3) · Assiut University (2) · CONRAD (2) · Estetra (2) · Population Council (2) · Sebela Women's Health Inc. (2) · University of Nebraska (2) · Catherine Anne Chappell (1) · Institute of Tropical Medicine, Belgium (1) · Mount Sinai Hospital, Canada (1) · Mylan Pharmaceuticals Inc (1) · Premier Research (1)
United States (17) · Germany (9) · Netherlands (3) · Uganda (3) · Chile (2) · Dominican Republic (2) · Egypt (2) · Finland (2) · United Kingdom (2) · Belgium (1) · Canada (1) · France (1) · Hungary (1) · Norway (1) · Russia (1)
William J Bremner, MD, PhD (2) · Alfred Poindexter, MD (1) · Alison Edelman, MD (1) · Anita L Nelson, MD (1) · Catherine A Chappell, MD MSc (1) · Christine K Mauck, MD (1) · Christine Klipping (1) · Dan Apter, M.D. (1) · David Archer, MD (1) · David F Archer, MD (1) · David Turok, MD (1) · Elizabeth M Stringer, MD (1) · Herman Ellman, MD (1) · John K Amory, MD, MPH (1)
PMID 17494097, PMID 16940442, PMID 17303493, PMID 17579200, PMID 18046048, PMID 18077826, PMID 18413423, PMID 20634186, PMID 21721593, PMID 22222193, PMID 23265980, PMID 24043457, PMID 24726226, PMID 25393993, PMID 25751199, PMID 25880636, PMID 26181091, PMID 26646680, PMID 26965870, PMID 30203681, PMID 31370907, PMID 32168217, PMID 33970869, PMID 36648744, PMID 38458408
U54HD042454 (3), 2009 (2), K23HD045386 (2), 2004 (1), 2008 (1), 2016 (1), 2018 (1), R01HD085887 (1), R21HD074462 (1)