39 completed, 6 unknown, 3 recruiting, 3 terminated. 23 Phase 4, 8 Phase 2, 7 Phase 3, 5 Not applicable, 2 Early Phase 1.
Follow etonogestrel: new trials by email Literature Review of etonogestrel trials Research Report on etonogestrel
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| the Effect of Implanon on Menstrual Patterns Implanon (Etonogestrel) - Menstrual Irregularities | Not yet recruiting | Assiut University | 200 | 2025-05-01 | 2025-04-23 | |
| Body Composition and Sport Performance Among Young Female Soccer Players Using Subdermic Etonogestrel Implanon NXT® subdermal implant, Etonogestrel 68mg implant - Menstrual Symptoms | Early Phase 1 | Suspended | Maíta Poli de Araújo | 40 | 2025-04-01 | 2025-08-14 |
| The Use of Etonogestrel Contraceptive Implant as Treatment for Endometrial Hyperplasia Without Atypia: A Cohort Study Etonogestrel implant - Endometrial Hyperplasia Without Atypia | Unknown | University of the Philippines | 60 | 2024-06-01 | 2024-04-22 | |
| Pharmacokinetic Interactions of ENG Subdermal Implants with Long-Acting Cabotegravir (CAB-LA) and LA Rilpivirine (RPV-LA) (CARLA) Etonogestrel (ENG) Subdermal Implants - HIV-1-infection | Phase 4 | Withdrawn | Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections | 2024-01-01 | 2024-12-13 | |
| Casea S Contraceptive Implants (Casea S) Trial 22.2 mg Etonogestrel (ENG), 44.4 mg Etonogestrel (ENG) - Contraception | Phase 1 | Active not recruiting | FHI 360 | 20 | 2023-12-13 | 2026-04-08 |
| Etonogestrel (ENG) Implant Insertion for Emergency Contraception With Oral Levonorgestrel (LNG) vs Placebo Etonogestrel implant with Oral Levonorgestrel emergency contraception 1.5mg, Etonogestrel implant with oral placebo - Emergency Contraception | Phase 4 | Recruiting | Lori Gawron | 790 | 2023-11-06 | 2026-06-02 |
| Effects of the Contraceptive Implant in Women With Sickle Cell Disease Nexplanon 68 MG Drug Implant - Sickle Cell Disease | Phase 4 | Active not recruiting | University of Pennsylvania | 22 | 2023-08-02 | 2026-06-12 |
| Endometrial Biopsy in Progestin Contraceptive Users DMPA, Etonogestrel implant - Contraception | Early Phase 1 | Completed | Oregon Health and Science University | 59 | 2023-07-01 | 2026-10-14 |
| Etonogestrel Implants Protect Ovarian Reserve Function in Systemic Lupus Erythematosus Etonogestrel - Systemic Lupus Erythematosus | Phase 2 / Phase 3 | Unknown | Sixth Affiliated Hospital, Sun Yat-sen University | 180 | 2023-04-01 | 2023-03-30 |
| Failed Endometrial Ablation Treatment With Implantable Progesterone (FEAT) Study Etonogestrel 68mg implant - Abnormal Uterine Bleeding, Dysmenorrhea | Phase 2 | Withdrawn | Saskatchewan Health Authority - Regina Area | 2022-07-01 | 2025-11-25 | |
| Etonogestrel Implant as Emergency Contraception Etonogestrel implant - Contraception | Phase 4 | Recruiting | University of Colorado, Denver | 12 | 2022-04-01 | 2026-08-11 |
| An Open-label, Randomized, 2-Period, Crossover, Pharmacokinetics Study LSP-5415 (etonogestrel/ethinyl estradiol vaginal ring), NuvaRing Vaginal Ring - Pregnancy Prevention | Phase 2 | Completed | Lupin Research Inc | 40 | 2022-02-24 | 2022-07-19 |
| Kuwa Free! - Live Free! Cabotegravir/ Rilpivirine, Etonogestrel (ETG) implant, Intramuscular depo-medroxyprogesterone acetate (IM DMPA) - HIV Infections, Contraception | Not applicable | Recruiting | University of Alabama at Birmingham | 700 | 2021-11-26 | 2026-04-13 |
| Evaluation of Pharmacokinetic Drug-drug Interactions Between Hormonal Contraceptives and Doravirine-containing ART Among Women Living With HIV in South Africa Etonogestrel (ETG) implant, Intramuscular depo-medroxyprogesterone acetate (IM DMPA), Sub-cutaneous medroxyprogesterone acetate (SC MPA) - HIV Infections, Contraception | Phase 4 | Completed | University of Alabama at Birmingham | 110 | 2021-11-17 | 2025-04-08 |
| Progesterone Containing Contraceptive Methods on Endogenous Progesterone Level Depo-Provera, Implanon, Norgestrel - Progesterone, Contraceptive Methods | Completed | Tanta University | 80 | 2021-03-30 | 2023-02-24 | |
| Impact of Contraceptives on Cervico-Vaginal Mucosa Copper IUD, Etonogestrel implant, Levonorgestrel IUS - Mucosal Inflammation, Contraceptive; Complications, Intrauterine | Phase 4 | Completed | Eastern Virginia Medical School | 112 | 2021-03-01 | 2023-08-25 |
| A Study to Assess Contraceptive Efficacy and Safety of Etonogestrel (ENG) Implant Beyond 3 Years of Use (MK-8415-060) Radiopaque Etonogestrel (ENG) Implant - Contraception | Phase 3 | Completed | Organon and Co | 498 | 2020-11-19 | 2026-02-18 |
| Shoulder Contraceptive Implant Study Etonogestrel implant - Contraception | Phase 4 | Completed | University of Colorado, Denver | 5 | 2020-10-14 | 2023-06-08 |
| Does Vaginal Delivery of Combined Hormonal Contraception Affect the Risk of Metabolic Syndrome in Overweight/Obese Women With PCOS Etonogestrel/ethinyl estradiol vaginal ring - Polycystic Ovary Syndrome | Phase 4 | Completed | Andrea Roe, MD, MPH | 22 | 2020-09-03 | 2026-09-28 |
| Nexplanon Use in Women Primarily Choosing a Combined Oral Contraceptive Etonogestrel contraceptive implant - Contraception | Phase 4 | Completed | University of California, Davis | 120 | 2020-08-13 | 2024-05-22 |
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Breast Feeding (3) · HIV Infections (3) · Acquired Immunodeficiency Syndrome (2) · Anemia, Sickle Cell (2) · Contraception Behavior (2) · Metrorrhagia (2) · Body Weight (1) · Dysmenorrhea (1) · Endometriosis (1) · Headache (1) · Hemorrhage (1) · Lupus Erythematosus, Systemic (1) · Menstruation Disturbances (1) · Mucositis (1) · Opioid-Related Disorders (1)
Organon and Co (8) · Assiut University (3) · Bayer (3) · University of Colorado, Denver (3) · University of Pittsburgh (3) · Eastern Virginia Medical School (2) · FHI 360 (2) · Oregon Health and Science University (2) · University of Alabama at Birmingham (2) · University of California, Davis (2) · University of Pennsylvania (2) · University of Sao Paulo (2) · Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections (1) · Andrea Roe, MD, MPH (1) · Boston University (1)
United States (27) · Brazil (5) · Egypt (3) · Finland (3) · South Africa (3) · Sweden (3) · Uganda (3) · United Kingdom (3) · Argentina (2) · France (2) · Kenya (2) · Norway (2) · Puerto Rico (2) · Thailand (2) · Australia (1)
Aaron Lazorwitz, MD (1) · Adriana Weinberg, MD (1) · Alicia Smith, PhD (1) · Alison Edelman, MD (1) · Andrea Roe, MD MPH (1) · Andrea Thurman (1) · Anna Wald, MD, MPH (1) · Beatrice Chen, MD, MPH (1) · Carolina S Vieira, MD, PhD (1) · Catherine A Chappell, MD (1) · Catherine A Chappell, MD MSc (1)
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2014 (1), 2015 (1), R01AI155052 (1), R01HD095741 (1), UM1AI068636 (1)