17 completed, 6 unknown, 5 terminated, 4 recruiting. 36 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 36 | Completed 17, Unknown 6, Terminated 5, Recruiting 4, Active not recruiting 2, Withdrawn 2 |
Follow Chronic Venous Insufficiency: new trials by email Literature Review of Chronic Venous Insufficiency trials Research Report on Chronic Venous Insufficiency
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Photobiomodulation on Healing of Venous Leg Ulcers Photobiomodulation Therapy, Sham Photobiomodulation, Compression Therapy - Venous Leg Ulcer (VLU), Venous Hypertension Ulcers | Not applicable | Recruiting | University of Nove de Julho | 102 | 2026-08-03 | 2026-09-09 |
| The Influence of Laser Crossectomy With Different Wavelengths on Varicose Vein Progression Laser crossectomy on 1470 nm, Laser crossectomy on 1940 nm, Standard EVLT with a stump - Varicose Veins, Chronic Venous Insufficiency | Not applicable | Recruiting | Pirogov Russian National Research Medical University | 400 | 2026-01-20 | 2026-03-04 |
| Clinical Study to Evaluate the Effectiveness and Health Economics of a Novel Portable Non-Pneumatic Active Compression Device (NPCD) for Lymphedema/Phlebolymphedema Dayspring - Phlebolymphedema, Lymphedema | Not applicable | Recruiting | Koya Medical, Inc. | 100 | 2024-05-13 | 2026-05-04 |
| Extracorporeal Flow Abolition in Relation With Primary Insufficiency of Great Saphenous Veins (GSV) Using High Intensity Focused Ultrasound (HIFU) Generated by Sonovein: A Multi Center Prospective Pivotal Study Sonovein Treatment - Chronic Venous Insufficiency | Not applicable | Completed | Theraclion | 70 | 2023-10-12 | 2025-06-19 |
| Long-term Effects of Inspiratory Muscle Training in Chronic Venous Insufficiency Training group: Inspiratory muscle training, Control group: Thoracic expansion exercise - Chronic Venous Insufficiency | Not applicable | Terminated | Izmir Democracy University | 40 | 2023-09-15 | 2025-05-18 |
| Venclose digiRF System Post Market Study Venclose System (digiRF generator w EVSRF catheter), Venclose MAVEN System (digiRF generator w MAVEN catheter) - Venous Reflux, Chronic Venous Insufficiency | Not applicable | Active not recruiting | C. R. Bard | 203 | 2023-09-08 | 2026-03-18 |
| Inspiratory Muscle Training in Chronic Venous Diseases Inspiratuar Muscle Training Group, Thoracic Expansion Exercise Group - Chronic Venous Insufficiency | Not applicable | Completed | Izmir Democracy University | 40 | 2023-07-20 | 2025-01-17 |
| Daily Duration of Compression Treatment in Patients With Symptomatic Chronic Venous Disease Compression socks - Chronic Venous Insufficiency, Varicose Veins of Lower Limb | Not applicable | Unknown | Pirogov Russian National Research Medical University | 80 | 2023-02-15 | 2024-02-20 |
| Investigation of Femoropopliteal In Situ Valve Formation With the InterVene System (INFINITE-Canada) BlueLeaf Procedure - Chronic Venous Insufficiency | Not applicable | Withdrawn | Intervene, Inc. | 2022-10-01 | 2025-08-05 | |
| Efficacy of Active Versus Passive Methods in Chronic Venous Insufficiency Exercise Training, Massage, Neuromuscular Electrical Stimulation - Chronic Venous Insufficiency | Not applicable | Completed | Istanbul University - Cerrahpasa | 66 | 2022-09-13 | 2023-11-14 |
| A Clinical Study to Evaluate the Effectiveness of a Novel Portable Non-Pneumatic Active Compression Device vs. an Advanced Pneumatic Compression Device for Treating Lower Extremity Lymphedema Cross over Device (PCD or Dayspring - alternate to first group) - Lymphedema, Lymphedema of Leg | Not applicable | Completed | Koya Medical, Inc. | 121 | 2022-09-06 | 2025-12-12 |
| Best Endovenous Treatment, Including STenting, Versus Non-endovenous Treatment in Chronic Proximal Deep Venous Disease Deep venous stenting, Best medical therapy - Chronic Venous Insufficiency, Chronic Venous Thrombosis | Not applicable | Terminated | Imperial College London | 12 | 2022-09-03 | 2025-06-22 |
| Assessment of the Effect of Spa Therapy on the Quality of Life of Patients with Chronic Venous Insufficiency (NEYRAC) Spa therapy - Chronic Venous Insufficiency | Not applicable | Completed | Le Syndicat Intercommunal pour le Thermalisme et l'Environnement | 100 | 2022-07-11 | 2024-12-19 |
| The Effect of Inelastic Compression System on Quality of Life in People With Chronic Venous Insufficiency Sigvaris Compreflex Inelastic Compression Wrap - Chronic Venous Insufficiency | Not applicable | Completed | University of Miami | 30 | 2021-11-15 | 2025-04-09 |
| Study to Evaluate the Safety and Effectiveness of Dayspring for Lower Extremity Lymphedema Dayspring Active Wearable Compression System - Lymphedema, Lymphedema Lower Extremity | Not applicable | Completed | Koya Medical, Inc. | 24 | 2021-06-01 | 2026-02-17 |
| Venous Stent for the Iliofemoral Vein Investigational Clinical Trial Using the DUO Venous Stent System Duo Venous Stent System - May-Thurner Syndrome, Deep Vein Thrombosis | Not applicable | Completed | Vesper Medical, Inc. | 162 | 2020-11-30 | 2025-05-15 |
| Venclose RF Ablation System for the Treatment of IPVs Radiofrequency (RF) Thermal Ablation of Incompetent Perforator Veins - Chronic Venous Insufficiency | Not applicable | Completed | Venclose, Inc. | 27 | 2020-05-23 | 2022-05-27 |
| EU Post Market Clinical Follow-Up Study of the Venclose System for Saphenous Vein Incompetence Venclose RF System - Chronic Venous Insufficiency | Not applicable | Completed | Venclose, Inc. | 25 | 2020-05-11 | 2022-04-04 |
| Feasibility of the InnoVein Valve and Delivery System for Chronic Venous Insufficiency InnoVein Valve Treatment - Chronic Venous Insufficiency | Not applicable | Recruiting | InnoVein | 5 | 2020-01-15 | 2021-09-17 |
| Elastic Compression Stockings and Varicose Veins Recurrence Graduated Compression Stocking: continuous using, Graduated Compression Stocking: intermittent using - Varicose Veins, Chronic Venous Insufficiency | Not applicable | Active not recruiting | Pirogov Russian National Research Medical University | 319 | 2019-12-16 | 2025-06-13 |
Showing 20 of 36. Sign in to see all of them.
Varicose Veins (8) · Venous Insufficiency (8) · Lymphedema (3) · Edema (2) · Pain (2) · Varicose Ulcer (2) · Bites and Stings (1) · Gastroesophageal Reflux (1) · Lipodermatosclerosis (1) · May-Thurner Syndrome (1) · Motor Activity (1) · Postthrombotic Syndrome (1) · Recurrence (1) · Sleep Apnea Syndromes (1) · Sleep Apnea, Obstructive (1)
Cardiovascular Diseases (17) · Vascular Diseases (17) · Hemic and Lymphatic Diseases (3) · Lymphatic Diseases (3) · Pathological Conditions, Signs and Symptoms (3) · Embolism and Thrombosis (2) · Leg Ulcer (2) · Neurologic Manifestations (2) · Signs and Symptoms (2) · Skin Diseases (2) · Skin Ulcer (2) · Skin and Connective Tissue Diseases (2) · Thrombosis (2) · Varicose Veins (2) · Apnea (1)
Stockings, Compression (2) · Educational Status (1) · Exercise (1) · Low-Level Light Therapy (1) · Manual Lymphatic Drainage (1) · Massage (1)
Intervene, Inc. (3) · Koya Medical, Inc. (3) · Pirogov Russian National Research Medical University (3) · Izmir Democracy University (2) · Tactile Medical (2) · Venclose, Inc. (2) · Angiodynamics, Inc. (1) · Association Francaise pour la Recherche Thermale (1) · C. R. Bard (1) · Croydon Health Services NHS Trust (1) · Imperial College London (1) · InnoVein (1) · Istanbul University - Cerrahpasa (1) · Kyung Hee University Hospital at Gangdong (1) · Le Syndicat Intercommunal pour le Thermalisme et l'Environnement (1)
United States (12) · Russia (4) · Turkey (Türkiye) (3) · Australia (2) · France (2) · Ireland (2) · New Zealand (2) · United Kingdom (2) · Austria (1) · Brazil (1) · Canada (1) · Czechia (1) · Germany (1) · Poland (1) · Portugal (1)
Jeff Elkins (2) · Abdul H Sultan (1) · Alun Davies, PhD (1) · Evi Kalodiki, MD PhD FRCS (1) · Fedor Lurie, MD, PhD (1) · Hadar Lev-Tov, MD (1) · Jeffrey Carr, MD (1)
PMID 12756353, PMID 18692348, PMID 25505858, PMID 25650040, PMID 27052039, PMID 27638993, PMID 28818225, PMID 30149775, PMID 31806052, PMID 32205128, PMID 39968829, PMID 41850352