4 completed, 1 active not recruiting, 1 recruiting, 1 terminated. 8 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 8 | Completed 4, Active not recruiting 1, Recruiting 1, Terminated 1, Unknown 1 |
| Phase 2 | 3 | Active not recruiting 1, Completed 1, Unknown 1 |
Follow Chronic Myeloid Leukemia (CML): new trials by email Literature Review of Chronic Myeloid Leukemia (CML) trials Research Report on Chronic Myeloid Leukemia (CML)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| TACrolimus Targeted Immunosuppression Cessation in ALlogeneic HCT Tacrolimus, Early Tacrolimus Taper Strategy - GVHD, Hematopoietic Cell Transplantation (HCT) | Phase 1 | Recruiting | Stanford University | 50 | 2026-07-21 | 2026-08-17 |
| A First-in-Human Study of HLA-Partially to Fully Matched Allogenic Cryopreserved Deceased Donor Bone Marrow Transplantation for Patients With Hematologic Malignancies Ossium HPC Marrow, Bone Marrow Transplant, Pre-transplant conditioning - Myeloablative (MAC), Pre-transplant conditioning - Reduced Intensity (RIC) - Acute Leukemia, Acute Lymphoblastic Leukemia | Phase 1 / Phase 2 | Active not recruiting | Ossium Health, Inc. | 12 | 2024-08-16 | 2026-09-10 |
| The Absorption, Metabolism and Excretion of [14C] HQP1351 in Humans [14C] HQP1351 - Chronic Myeloid Leukemia (CML) | Phase 1 | Completed | Ascentage Pharma Group Inc. | 6 | 2019-11-19 | 2021-09-08 |
| CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant CliniMACS CD34+ Reagent System, Thiotepa, Cyclophosphamide - Chronic Myeloid Leukemia (CML), Acute Myelogenous Leukemia (AML) | Phase 1 / Phase 2 | Unknown | Diane George | 14 | 2013-06-03 | 2024-06-04 |
| A Study of Ponatinib in Japanese Participants With Chronic Myeloid Leukemia (CML) and Ph+ Acute Lymphoblastic Leukemia (ALL) ponatinib - Phase 1, ponatinib - Phase 2 - Chronic Myeloid Leukemia (CML), Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ ALL) | Phase 1 / Phase 2 | Completed | Ariad Pharmaceuticals | 35 | 2012-08-31 | 2022-06-13 |
| Glivec/Gleevec Pediatric (Age 1 to Less Than 4) PK Study in CML, Ph+ ALL Patients and Other Glivec/Gleevec® Indicated Hematological Disorders. Gleevec/Glivec - Chronic Myeloid Leukemia (CML), Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ ALL) | Phase 1 | Terminated | Novartis Pharmaceuticals | 3 | 2010-10-01 | 2012-03-13 |
| Natural Killer Cells and Bortezomib to Treat Cancer Bortezomib, NK cells - Chronic Myeloid Leukemia (CML), Pancreatic Ca | Phase 1 | Completed | National Heart, Lung, and Blood Institute (NHLBI) | 35 | 2008-08-01 | 2026-10-26 |
| Effect of Imatinib Mesylate and the Pharmacokinetics of Acetaminophen/Paracetamol in Patients With Newly Diagnosed, Previously Untreated Chronic Myeloid Leukemia in Chronic Phase (CML-CP) Imatinib/Acetaminophen - Chronic Myeloid Leukemia (CML) | Phase 1 | Completed | Novartis Pharmaceuticals | 12 | 2006-11-01 | 2016-04-21 |
Leukemia, Myelogenous, Chronic, BCR-ABL Positive (8) · Leukemia, Myeloid, Acute (3) · Myelodysplastic Syndromes (3) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (3) · Hematologic Diseases (2) · Leukemia (2) · Lymphoma (2) · Myeloproliferative Disorders (2) · Acquired Immunodeficiency Syndrome (1) · Anemia, Aplastic (1) · Anemia, Diamond-Blackfan (1) · Anemia, Refractory, with Excess of Blasts (1) · Anemia, Sickle Cell (1) · Bone Marrow Diseases (1) · Bone Marrow Failure Disorders (1)
Chronic Disease (8) · Disease Attributes (8) · Hemic and Lymphatic Diseases (8) · Pathologic Processes (8) · Pathological Conditions, Signs and Symptoms (8) · Bone Marrow Diseases (7) · Leukemia, Myeloid (7) · Neoplasms (7) · Neoplasms by Histologic Type (7) · Hematologic Diseases (6) · Leukemia (6) · Myeloproliferative Disorders (6) · Immune System Diseases (4) · Immunoproliferative Disorders (4) · Leukemia, Lymphoid (4)
Cyclophosphamide (2) · Imatinib Mesylate (2) · Melphalan (2) · Tacrolimus (2) · fludarabine phosphate (2) · Acetaminophen (1) · Alemtuzumab (1) · Bone Marrow Transplantation (1) · Bortezomib (1) · Busulfan (1) · Filgrastim (1) · Mesna (1) · Methylprednisolone (1) · Methylprednisolone Hemisuccinate (1) · Mycophenolic Acid (1)
Novartis Pharmaceuticals (2) · Ariad Pharmaceuticals (1) · Ascentage Pharma Group Inc. (1) · Diane George (1) · National Heart, Lung, and Blood Institute (NHLBI) (1) · Ossium Health, Inc. (1) · Stanford University (1)
United States (4) · China (1) · Japan (1) · Russia (1) · South Korea (1)
Diane George, MD (1) · Feng Shao, Doctor (1) · Richard W Childs, M.D. (1) · Vanessa Kennedy, MD (1)