8 recruiting, 3 completed, 2 active not recruiting, 2 not yet recruiting. 4 Not applicable, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Recruiting 2, Not yet recruiting 1, Withdrawn 1 |
| Phase 2 | 1 | Unknown 1 |
Follow Chronic Limb Threatening Ischemia: new trials by email Literature Review of Chronic Limb Threatening Ischemia trials Research Report on Chronic Limb Threatening Ischemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| ORbital Atherectomy for Lesion Preparation in Patients With Chronic Limb-threatening ischEmia Stealth 360™ Peripheral Orbital Atherectomy System from Abbott - Chronic Limb Threatening Ischemia, Chronic Limb-Threatening Ischemia | Recruiting | Cardiovascular and Interventional Radiological Society of Europe | 250 | 2026-08-31 | 2026-09-23 | |
| REsorbable SCaffolds With everolimUs-Elution for the Treatment of Infrapopliteal Artery Disease in Patients With Chronic Limb-threatening Ischemia Esprit BTK™ Everolimus Eluting Resorbable Scaffold from Abbott - Chronic Limb Threatening Ischemia, Chronic Limb-Threatening Ischemia | Recruiting | Cardiovascular and Interventional Radiological Society of Europe | 400 | 2026-08-31 | 2026-09-23 | |
| Vessel Recoil in Specific CLTI Populations Vessel recoil measurement 15 minutes post final treatment (angiographically) - Chronic Limb Threatening Ischemia | Recruiting | Medical University of Graz | 40 | 2026-07-01 | 2026-10-14 | |
| Transverse Tibial Transport for Chronic Limb-Threatening Ischemia (CLTI) Transverse Tibial Bone Transport, TrueLok Elevate - Chronic Limb Threatening Ischemia | Not applicable | Withdrawn | University Hospitals Cleveland Medical Center | 2026-01-05 | 2026-05-29 | |
| Intravascular Ultrasound for Peripheral Artery Disease Revascularization IVUS-guided strategy - Peripheral Arterial Disease(PAD), Chronic Limb Threatening Ischemia | Not applicable | Recruiting | Hamilton Health Sciences Corporation | 772 | 2025-12-05 | 2026-09-18 |
| Outcomes of Atherectomy and Balloon Angioplasty Compared to Conventional Angioplasty in Infra-popliteal Chronic Limb-Threatening Ischemia atherectomy, Percutaneous transluminal angioplasty of infra-popliteal arteries lesions with primary long - Chronic Limb Threatening Ischemia | Not applicable | Not yet recruiting | Assiut University | 60 | 2025-09-30 | 2025-08-13 |
| Symptomatic and Systemic Atherosclerotic Plaque Activity in Patients With Peripheral Arterial Disease Using Novel Imaging Whole body [68Ga]DOTATATE PET-CT, Whole body [18F]GP1 PET-CT, Whole body [18F]NaF PET-CT - Peripheral Arterial Disease, Chronic Limb Threatening Ischemia | Recruiting | University of Edinburgh | 100 | 2025-07-31 | 2026-09-18 | |
| Efficacy of the Ranger Drug-Coated Balloon in Treating BTK Lesions in Patients With CLTI drug-coated balloon - Chronic Limb Threatening Ischemia | Not yet recruiting | First Affiliated Hospital, Sun Yat-Sen University | 700 | 2025-06-30 | 2025-06-11 | |
| Revascularization of Single Vesrus Multiple Infrapopliteal Vessels in Chronic Limb Threatening Ischemia balloon angioplasty - Chronic Limb Threatening Ischemia, Infrapopliteal Arterial Occlusive Disease | Not applicable | Recruiting | Sohag University | 40 | 2025-06-25 | 2025-07-16 |
| Laser Atherectomy and Sirolimus-coated Balloon Angioplasty for CLTI Laser atherectomy followed by Sirolimus-coated balloon angioplasty of femoropopliteal or infrapopliteal or both arterial stenosis or occlusions - Chronic Limb Threatening Ischemia | Active not recruiting | Attikon Hospital | 55 | 2025-04-01 | 2026-10-05 | |
| Angioplasty With Shockwave IVL Catheter System in Femoropopliteal Lesions Shockwave balloons - Peripheral Artery Disease (PAD), Chronic Limb Threatening Ischemia | Recruiting | Liyuan Hospital of Tongji Medical College, Huazhong University of Science and Technology | 130 | 2024-12-01 | 2024-12-03 | |
| Multimodal Noninvasive Assessment of Peripheral Circulation in Chronic Limb-threatening Ischemia Chronic Limb Threatening Ischemia | Unknown | Tampere University | 150 | 2024-06-17 | 2024-06-20 | |
| Referrals for CLTI: Qualitative Study Qualitative interview - Chronic Limb Threatening Ischemia | Completed | University of Hull | 20 | 2023-01-10 | 2023-08-24 | |
| Sarcopenia and Peripheral Artery Disease With Chronic Limb Threatening Ischemia Not applicable- observational study - Sarcopenia, Peripheral Arterial Disease | Completed | Fudan University | 97 | 2023-01-01 | 2025-06-26 | |
| Clinical Outcomes Following Surgical Debridement of Diabetic Foot Infection with Borderline Vascularity PER CUTANEOUS TRANSLUMINAL ANGIOPLASTY - Chronic Limb Threatening Ischemia | Active not recruiting | Assiut University | 70 | 2023-01-01 | 2024-11-26 | |
| Can a Dedicated Chronic Limb-threatening Ischaemia (CLTI) Clinic Improve Patient Self-reported Quality of Life CLTI Clinic - Chronic Limb Threatening Ischemia | Completed | The Leeds Teaching Hospitals NHS Trust | 30 | 2022-11-17 | 2025-02-14 | |
| Durg Coated Balloon Angioplasty in Infrapopliteal Lesions drug-coated balloon - Arteriosclerosis, Peripheral Artery Disease | Recruiting | Liyuan Hospital of Tongji Medical College, Huazhong University of Science and Technology | 1000 | 2020-12-01 | 2026-03-25 | |
| Study of AMG0001 to Improve Ulcer Healing and Perfusion in Subjects With Peripheral Ischemic Ulcers AMG0001, Placebo - Peripheral Artery Disease, Ischaemic Ulcer of Lower Leg Due to Atherosclerotic Disease | Phase 2 | Unknown | AnGes USA, Inc. | 60 | 2020-01-30 | 2021-12-22 |
Chronic Limb-Threatening Ischemia (18) · Peripheral Arterial Disease (10) · Arteriosclerosis (1) · Calcinosis (1) · Cardiovascular Diseases (1) · Diabetes Mellitus (1) · Diabetic Foot (1) · Sarcopenia (1)
Arterial Occlusive Diseases (18) · Atherosclerosis (18) · Chronic Disease (18) · Disease Attributes (18) · Ischemia (18) · Pathologic Processes (18) · Pathological Conditions, Signs and Symptoms (18) · Peripheral Vascular Diseases (18) · Vascular Diseases (18) · Arteriosclerosis (17) · Cardiovascular Diseases (17) · Peripheral Arterial Disease (8) · Endocrine System Diseases (2) · Metabolic Diseases (2) · Nutritional and Metabolic Diseases (2)
Angioplasty, Balloon (1) · Atherectomy (1) · Dental Occlusion (1)
Assiut University (2) · Cardiovascular and Interventional Radiological Society of Europe (2) · Liyuan Hospital of Tongji Medical College, Huazhong University of Science and Technology (2) · AnGes USA, Inc. (1) · Attikon Hospital (1) · First Affiliated Hospital, Sun Yat-Sen University (1) · Fudan University (1) · Hamilton Health Sciences Corporation (1) · Medical University of Graz (1) · Sohag University (1) · Tampere University (1) · The Leeds Teaching Hospitals NHS Trust (1) · University Hospitals Cleveland Medical Center (1) · University of Edinburgh (1) · University of Hull (1)
United Kingdom (5) · China (4) · Egypt (2) · United States (2) · Austria (1) · Canada (1) · Finland (1) · Greece (1)
Marianne Brodmann, Univ.-Prof. Dr. med. (2) · Raghu Lakshminarayan, Dr (2) · Assad Khan, BMBS (1) · David G Armstrong, MD, DPM, PhD (1) · Ian Chetter, MD (1) · Lianrui Guo (1) · Michael S Conte, MD (1) · Niku Oksala, MD, PhD, DSc (1) · Rachael O Forsythe, MBChB, PhD, FRCS (Vascular) (1) · Zibo Feng (1)