10 not yet recruiting, 8 recruiting, 2 completed, 1 active not recruiting. 14 Not applicable, 2 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 14 | Not yet recruiting 7, Recruiting 6, Completed 1 |
| Phase 4 | 2 | Not yet recruiting 1, Recruiting 1 |
Follow Chronic Kidney Disease (Stages 4 and 5): new trials by email Literature Review of Chronic Kidney Disease (Stages 4 and 5) trials Research Report on Chronic Kidney Disease (Stages 4 and 5)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Kidney RISE: Randomized Integrated Supportive CarE Trial Kidney RISE - Chronic Kidney Disease (Stages 4 and 5) | Not applicable | Not yet recruiting | NYU Langone Health | 280 | 2027-05-01 | 2026-08-03 |
| Primary Palliative Care - a Feasibility Cluster Trial Primary Palliative Care Complex Intervention (PrimPal) - Palliative Care, Primary Palliative Care | Not applicable | Not yet recruiting | University of Coimbra | 30 | 2026-10-01 | 2026-08-03 |
| The Adaptive Platform Trial for Kidney Disease APT-KIDNEY platform participation - Kidney Disease, Chronic Kidney Disease (Stages 4 and 5) | Not applicable | Not yet recruiting | Nicholas Carlson | 5000 | 2026-10-01 | 2026-06-10 |
| Safety of a Healthy Plant-based Diet With Higher Potassium Content, Compared to a Healthy Plant-based Diet With Limited Potassium Content in Patients With Chronic Kidney Disease: A Pilot Study Healthy plant-based diet (healthy-PBD), Potassium-restricted plant-based diet - Hyperkalemia, Chronic Kidney Disease (Stages 4 and 5) | Not applicable | Recruiting | Karolinska Institutet | 30 | 2026-09-29 | 2026-10-02 |
| Inspiratory Muscle Training During Hemodialysis Inspiratory Muscle Training, Usual Care - Chronic Kidney Disease (Stages 4 and 5), Hemodialysis | Not applicable | Not yet recruiting | Tecsam - Tecnologia e Servicos Medicos | 53 | 2026-09-20 | 2026-09-10 |
| Feasibility of the COMFORT (COmplex Symptom Management Intervention FOR adulTs With Advanced Kidney Disease) Intervention for Adults With Advanced Kidney Disease and Their Informal Caregivers COMFORT Intervention, Usual Care - Chronic Kidney Disease (Stages 4 and 5) | Not applicable | Not yet recruiting | University of Aarhus | 112 | 2026-09-15 | 2026-09-11 |
| Thyroid Hormones in CKD Laboratory measurements - Chronic Kidney Disease (Stages 4 and 5) | Not yet recruiting | Mario Negri Institute for Pharmacological Research | 51 | 2026-09-01 | 2026-06-23 | |
| Prospective Analysis of Self Medication With Phytotherapy in Nephropatic Patients. series of questions which can change patient care - Chronic Kidney Disease (Stage 3-4), Chronic Kidney Disease (Stages 4 and 5) | Not applicable | Recruiting | Centre Hospitalier Universitaire de la Réunion | 400 | 2026-07-28 | 2026-09-16 |
| Symptom Monitoring With Supported Feedback in Advanced Chronic Kidney Disease Electronic patient-reported outcome measure (ePROM) for symptom monitoring - Chronic Kidney Disease (Stages 4 and 5), Health Related Quality of Life | Not applicable | Recruiting | Massachusetts General Hospital | 70 | 2026-06-11 | 2026-06-22 |
| CANagliflozin In DIALysis Patients Invokana 300 mg and 100 mg tablet - Dialysis, Chronic Kidney Disease (Stages 4 and 5) | Phase 4 | Not yet recruiting | University Medical Center Groningen | 10 | 2026-06-01 | 2026-05-06 |
| The Practicality and Utility of Measured vs Estimated GFR in adCKD Iohexol Inj 300 MG/ML Diagnostic aid/agent used to measure glomerular filtration rate (GFR) - Chronic Kidney Disease (Stages 4 and 5), Chronic Kidney Disease 5D | Not yet recruiting | Manchester University NHS Foundation Trust | 150 | 2026-02-01 | 2026-03-04 | |
| Physical Exercise to Prevent Mild-cognitive Impairment in Patients With Kidney Disfunctions Exercise, Control (Standard treatment) - Chronic Kidney Disease (Stages 4 and 5), Mild Cognitive Impairment (MCI) | Not applicable | Not yet recruiting | Biogem s.c.ar.l. | 124 | 2026-01-01 | 2025-09-08 |
| Respiratory Biofeedback Added to Strengthening Training in Patients With Chronic Kidney Disease Diaphragmatic biofeedback combined with respiratory muscle training, PLACEBO INTERVENTION - Chronic Kidney Disease (Stages 4 and 5) | Not applicable | Not yet recruiting | Universidad de Granada | 24 | 2026-01-01 | 2026-01-27 |
| Outcomes of Physiologic Insulin Resensitization (PIR) in Patients With Chronic Kidney Disease and Type 2 Diabetes Mellitus Physiologic Insulin Resensitization (PIR) - Chronic Kidney Disease (Stages 4 and 5), Kidney Disease | Not applicable | Recruiting | Well Cell Global | 120 | 2025-10-14 | 2026-08-04 |
| Probiotic and Prebiotic Supplementation in Peritoneal Dialysis Patients Synbiotic, Placebo - Chronic Kidney Disease (Stages 4 and 5), Peritoneal Dialysis (PD) | Not applicable | Recruiting | Hospital Universitario Dr. Jose E. Gonzalez | 60 | 2025-10-03 | 2026-07-10 |
| ACE Reno, Pico Cell Matrix and Its Effect on eGFR in Chronic Kidney Diseases ACE Reno - Hypertensive Nephropathy, Auto Immune Disorders | Phase 4 | Recruiting | Ace Cells Lab Limited | 300 | 2025-09-20 | 2025-09-23 |
| Deceased Donor Kidney Storage at 10 Celsius Versus Conventional Storage 10˚C deceased donor kidney storage using Traferox XPort - End Stage Chronic Renal Failure, Chronic Kidney Disease (Stages 4 and 5) | Not applicable | Recruiting | Vanderbilt University Medical Center | 30 | 2024-11-18 | 2026-04-06 |
| Assessment of Protein Intake Using 2 Types of Nutritional Collection in Chronic Kidney Disease. 3-day dietary record, Food Frequency Questionnaire (FFQ) - Chronic Kidney Disease (stages 4 and 5) | Recruiting | Assistance Publique Hopitaux De Marseille | 60 | 2024-11-15 | 2024-11-19 | |
| Identification of Patients With Advanced Chronic Diseases in Need of Palliative Care Cancer, Chronic Liver Disease (CLD) | Active not recruiting | Infanta Leonor University Hospital | 200 | 2024-02-01 | 2026-06-10 | |
| Outcome of Use of a Novel Modulator of Oxidative Phosphorylation on Kidney Function in Patients With Progressive Chronic Kidney Disease QRX-3, Eseronate - Chronic Kidney Disease (Stage 3-4), Chronic Kidney Disease (Stages 4 and 5) | Completed | Neukidney Inc. | 45 | 2021-05-20 | 2025-09-08 |
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Renal Insufficiency, Chronic (21) · Kidney Diseases (4) · Chronic Disease (1) · Cognitive Dysfunction (1) · Delayed Graft Function (1) · Diabetes Mellitus (1) · Diabetes Mellitus, Type 2 (1) · Diabetic Nephropathies (1) · Hyperkalemia (1) · Hypertensive Nephropathy (1) · Inflammation (1) · Kidney Failure, Chronic (1) · Motor Activity (1) · Neoplasms (1) · Proteinuria (1)
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Candan Z Algun, PT, PhD (1) · Dr. Alaa Abdelkarim M Fouad, MRCPUK SEC (1) · Giuseppe Remuzzi, M.D. (1) · Jennifer Scherer, MD, MS, FASN (1) · Marie Carmen Valenza, PhD (1) · Sungchun Lee, MD (1) · Thomas Lindsay (1)
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