7 recruiting, 2 not yet recruiting, 2 unknown, 1 completed. 5 Not applicable, 3 Phase 3, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Completed 1, Not yet recruiting 1, Recruiting 1, Unknown 1, Withdrawn 1 |
| Phase 3 | 3 | Recruiting 3 |
| Phase 1 | 1 | Not yet recruiting 1 |
| Phase 2 | 1 | Not yet recruiting 1 |
Follow Chondral Defect: new trials by email Literature Review of Chondral Defect trials Research Report on Chondral Defect
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study Comparing Two Methods for the Treatment of Large Chondral and Osteochondral Defects of the Knee MACT, AMT - Articular Cartilage Defect, Chondral Defect | Not applicable | Not yet recruiting | Centre Hospitalier Universitaire Vaudois | 80 | 2026-12-01 | 2026-03-12 |
| A Study of MACI in Patients Aged 17 to 65 Years With Symptomatic Chondral or Osteochondral Defects of the Ankle autologous cultured chondrocytes on porcine collagen membrane, Bone Marrow Stimulation - Chondral Defect, Articular Cartilage Defect | Phase 3 | Recruiting | Vericel Corporation | 309 | 2026-05-28 | 2026-11-05 |
| EB-OC for the Treatment of Focal Chondral/Osteochondral Defects in the Knee EB-OC Graft Implantation, Abrasion chondroplasty - Chondral Defect, Osteochondral Defect | Phase 1 / Phase 2 | Not yet recruiting | Epibone, Inc. | 36 | 2026-01-01 | 2025-03-26 |
| The Biomechanical Outcomes of Autologous Chondrocyte Implantation Autologous Chondrocyte Implantation (ACI) - Chondral Defect | Recruiting | University of Manchester | 47 | 2024-04-22 | 2026-05-07 | |
| Effect of PRP, PPP, & BMAC on Functional Outcomes Following Hip Arthroscopy for Acetabular Labral Pathologies Bone marrow aspirate concentrate (BMAC), Control - Acetabular Labrum Tear, Femoro Acetabular Impingement | Phase 3 | Recruiting | Massachusetts General Hospital | 160 | 2023-08-30 | 2024-11-20 |
| AMIC vs. MFx in the Ankle Microfracture (MFx), Chondro-Gide® - Osteochondral Lesion of Talus, Chondral Defect | Not applicable | Withdrawn | Geistlich Pharma AG | 2023-04-28 | 2024-03-18 | |
| Evaluation of Treatment of Osteoarthritis of the Knee in the Form of Chondromalacia of the Articular Cartilage Treated in the Arthroscopic Technique With the Use of:Autogenous Transplantation of Fragmented Adipose Tissue,PRP GF,Mesenchymal Cells,Hyaluronic Acid-low Molecular Weight and Cross-linked Autogenous transplant of fragmented adipose tissue taken from abdominal integuments, PRP GF (platelet-rich plasma with growth factors), Mesenchymal cells centrifuged from bone marrow cells taken from the iliac crest - Osteoarthritis, Knee, Chondral Defect | Not applicable | Completed | eMKa MED Medical Center | 150 | 2022-12-12 | 2025-08-07 |
| A Comparison of JointRep® and Microfracture in Repair of Cartilage Lesions on the Femoral Condyle or Trochlea, JointRep®, Microfracture - Chondral Defect, Articular Cartilage Defect | Not applicable | Unknown | Oligo Medic Pty Ltd | 185 | 2021-09-22 | 2024-03-20 |
| Use of BMAC With Hip Arthroscopy Treatment of FAI and Labral Tear BMAC - Acetabular Labrum Tear, Femoro Acetabular Impingement | Recruiting | Massachusetts General Hospital | 400 | 2019-09-06 | 2025-10-27 | |
| A Study of MACI in Patients Aged 10 to 17 Years With Symptomatic Chondral or Osteochondral Defects of the Knee MACI, microfracture - Chondral Defect, Osteochondritis Dissecans (OCD) | Phase 3 | Recruiting | Vericel Corporation | 45 | 2018-10-24 | 2026-11-03 |
| An Observational, Prospective Study of Patients With Chondral and/or Osteochondral Defects of the Knee Treated With NAMIC NAMIC: nanofractured autologous matrix-induced chondrogenesis - Chondral Defect, Osteochondral Defect | Unknown | Jordi Villalba Modol | 24 | 2018-07-18 | 2018-08-10 | |
| Introduction of ACI for Cartilage Repair autologous chondrocytes - Articular Cartilage Defect, Chondral Defect | Not applicable | Recruiting | Centre Hospitalier Universitaire Vaudois | 218 | 2017-09-01 | 2026-03-11 |
| Knee Registry (Knieregister) Knee Pathology, Osteoarthritis, Knee | Recruiting | UMC Utrecht | 1000000 | 2017-01-01 | 2023-12-05 |
Osteochondritis (3) · Cartilage Diseases (2) · Femoracetabular Impingement (2) · Fractures, Stress (2) · Osteoarthritis (2) · Osteoarthritis, Knee (2) · Osteochondritis Dissecans (2) · Bone Diseases (1) · Connective Tissue Diseases (1) · Musculoskeletal Diseases (1)
Musculoskeletal Diseases (7) · Arthritis (4) · Bone Diseases (4) · Joint Diseases (4) · Rheumatic Diseases (4) · Skin and Connective Tissue Diseases (4) · Connective Tissue Diseases (3) · Cartilage Diseases (2) · Fractures, Bone (2) · Osteoarthritis (2) · Osteochondritis (2) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Wounds and Injuries (2)
Arthroplasty, Subchondral (2) · Intercellular Signaling Peptides and Proteins (1)
Centre Hospitalier Universitaire Vaudois (2) · Massachusetts General Hospital (2) · Vericel Corporation (2) · Epibone, Inc. (1) · Geistlich Pharma AG (1) · Jordi Villalba Modol (1) · Oligo Medic Pty Ltd (1) · UMC Utrecht (1) · University of Manchester (1) · eMKa MED Medical Center (1)
United States (4) · Switzerland (2) · United Kingdom (2) · Australia (1) · Canada (1) · Netherlands (1) · Poland (1) · Spain (1)
Bruce Caldwell, MBBS, FRACS (1) · Despoina Natsiou Schmiady, Dr. (1) · Gwenllian F Tawy, PhD (1) · Jonathan Hopper, BSc (Hons), MB ChB, FRCSEd (1) · Roel Custers, Dr (1) · Sarindr Bhumiratana, PhD (1) · Scott D Martin, MD (1) · Scott D. Martin, MD (1) · Torres Paulo, Mr. (1)