Cervical Ripening: Clinical Trials

64 trials for Cervical Ripening, newest first

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35 completed, 8 unknown, 6 terminated, 5 withdrawn. 32 Not applicable, 14 Phase 3, 9 Phase 4, 6 Phase 2.

By phase and status

PhaseTrialsStatus
Not applicable32Completed 15, Terminated 4, Active not recruiting 3, Not yet recruiting 3, Recruiting 3, Unknown 2, Withdrawn 2
Phase 314Completed 8, Unknown 2, Withdrawn 2, Recruiting 1, Terminated 1
Phase 49Completed 5, Unknown 3, Terminated 1
Phase 26Completed 4, Unknown 1, Withdrawn 1

Follow Cervical Ripening: new trials by email Literature Review of Cervical Ripening trials Research Report on Cervical Ripening

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Improving the Childbirth Experience for Women Who Have Undergone Cervical Ripening by Involving Them in the Choice of Ripening Technique
The patient will be offered the various possible methods of inducing cervical ripening, and the choice of method will be left to her, Standard Care (in control arm) - Pregnancy, Cervical Ripening
Not applicableNot yet recruitingCentre Hospitalier Régional Metz-Thionville2042026-09-012026-10-02
Safety and Feasibility of the INGA Sensor System for Fetal and Uterine Monitoring During Cervical Ripening
Cervical ripening, labor Induction, uterus and fetal monitoring - Induced Labor, Cervical Ripening
Not applicableNot yet recruitingAalto University152026-09-012026-09-29
Evaluation of the INGA Sensor System for Fetal and Uterine Monitoring During Cervical Ripening
Cervical ripening, labor Induction, uterus and fetal monitoring - Induction of Birth, Cervical Ripening
Not applicableWithdrawnAalto University2026-08-012026-09-04
Open, Randomized Feasibility Trial on the Safety and Performance of the INGA Catheter for Labor Induction
INGA Catheter, Currently used single balloon catheter - Induction of Birth, Cervical Ripening
Not applicableTerminatedAalto University122026-07-032026-09-04
Safety and Usability of the Inga Catheter for Labor Induction (INGA-MDP)
Cervical ripening, labor induction - Induction of Labor, Cervical Ripening
Not applicableTerminatedAalto University422026-07-012026-09-04
Cervical Ripening Balloon Compared With Vaginal Misoprostol for Cervical Ripening in Obese Woman at Term
Cervical folleys, Misoprostol - Cervical Ripening
Not applicableActive not recruitingHUDDA Ahmad1082026-05-012026-07-06
PGE2 Followed by Oxytocin vs Oxytocin in Term PROM (POXY-PROM)
Sequential Induction: Dinoprostone Followed by Oxytocin, Immediate Oxytocin Induction - Premature Rupture of Fetal Membranes, Labor, Induced
Not applicableRecruitingNational Hospital of Obstetrics and Gynecology4502026-02-102026-02-20
Combined Nipple Stimulation and Foley Balloon for Cervical Ripening
Foley balloon catheter with nipple stimulation, Mechanical cervical ripening with Foley catheter - Induction of Labor, Cervical Ripening
Not applicableNot yet recruitingWestern Galilee Hospital-Nahariya1002026-01-012026-01-05
Comparison of Vaginal PGE2 (Dinoprostone) and Vaginal Misoprostol for Induction of Labour in Primigravid Term Pregnancy
Misoprostol, Dinoprostone 3 mg - Labor, Induced, Term Pregnancy
Not applicableActive not recruitingMayo Hospital Lahore2402025-10-292026-04-30
The SWEEP Trial: a Randomized Controlled Trial
Membrane sweeping - Membrane Stripping, Cervical Ripening
Not applicableRecruitingUniversity of Aarhus15362025-06-182025-09-02
Latent Phase Membrane Stripping for Caesarean Section Reduction
Hamilton maneuver - Cesarean Delivery, Cervical Ripening
Not applicableCompletedRicardo A Gutierrez Ramirez, MD, MSc, FACOG712025-01-312025-12-04
Membrane Stripping for Cervical Ripening
Double Baloon Catheter, Membrane Stripping, PGE2 - Labor, Induced, Cervical Ripening
Not applicableRecruitingMeir Medical Center4002024-08-072026-04-15
Cervical Ripening With Misoprostol vs Isosorbide Mononitrate ; A Parallel -Arm Randomized Controlled Trial
Misoprostol 25 µg Vaginal, Isosorbide Mononitrate - Cervical Ripening
Not applicableActive not recruitingRaid M. Al-Ani802024-01-012025-08-13
Heated Saline in Cervical Balloon for Labor Induction, a RCT
Warm group, Room temperature group - Cervical Ripening, Induction of Labor
Not applicableCompletedBegona Martinez de Tejada2902023-10-162025-06-05
Balloon + Oxytocin Versus Oral Misoprostol to Induce Labor in Case of PROM (RUBAPRO2)
Balloon for cervical ripening (Teleflex French Dufour catheter CH20 reference 174000), Oxytocin, Misoprostol Oral Tablet - Induction of Labor, Cervical Ripening
Phase 4TerminatedUniversity Hospital, Clermont-Ferrand1522023-01-182026-10-15
Significance of Misoprostol-induced Cervical Ripening Prior to Hysteroscopy
Misoprostol 400mcg Tab, Placebo - Hysteroscopy, Cervical Ripening
Not applicableCompletedHayat Abad Medical Complex, Peshawar5392022-08-012024-12-10
Comparing Methods for Balloon Catheter Inserting: View Guided (Speculum) Versus Manual Guided at Cervical Examination
balloon catheter insertion approach for labor induction - Cervical Ripening
Not applicableUnknownWestern Galilee Hospital-Nahariya1002022-01-102022-04-01
Oxytocin vs Prostaglandins for Labor Induction of Women With an Unfavorable Cervix After 24h of Cervical Ripening
Prostaglandins, Oxytocin - Cervical Ripening, Unfavorable Cervix
Phase 3RecruitingUniversity Hospital, Tours14942021-09-282026-07-27
Patient Satisfaction During Artificial Induction of Labor by Cervical Ripening
Cervical Ripening
CompletedUniversity Hospital, Strasbourg, France8002021-08-062023-12-12
General Drug Use-results Survey on PROPESS Vaginal Inserts in Treatment for Initiation of Cervical Ripening in Patients at Term (From 37 Completed Weeks of Gestation)
PROPESS Cohort - Cervical Ripening, Pregnancy
CompletedFerring Pharmaceuticals4092021-02-282023-04-26

Showing 20 of 64. Sign in to see all of them.

Narrower conditions

Fetal Membranes, Premature Rupture (3)  ·  Patient Satisfaction (2)  ·  Pregnancy, Prolonged (2)  ·  Dilatation, Pathologic (1)  ·  Menorrhagia (1)  ·  Premature Birth (1)

Broader conditions

Female Urogenital Diseases and Pregnancy Complications (7)  ·  Urogenital Diseases (7)  ·  Pregnancy Complications (6)  ·  Obstetric Labor Complications (4)  ·  Behavior (2)  ·  Health Behavior (2)  ·  Pathological Conditions, Signs and Symptoms (2)  ·  Treatment Adherence and Compliance (2)  ·  Female Urogenital Diseases (1)  ·  Genital Diseases (1)  ·  Genital Diseases, Female (1)  ·  Hemorrhage (1)  ·  Menstruation Disturbances (1)  ·  Obstetric Labor, Premature (1)  ·  Pathologic Processes (1)

Interventions

Dinoprostone (18)  ·  Misoprostol (18)  ·  Oxytocin (6)  ·  Labor, Induced (4)  ·  isosorbide-5-mononitrate (3)  ·  Fetal Monitoring (2)  ·  KLK15 protein, human (1)  ·  Mutagenesis, Insertional (1)  ·  Nitric Oxide Donors (1)  ·  Prostaglandins (1)  ·  Standard of Care (1)  ·  Therapeutics (1)

Sponsors

Ferring Pharmaceuticals (9)  ·  Aalto University (4)  ·  Meir Medical Center (2)  ·  Western Galilee Hospital-Nahariya (2)  ·  Begona Martinez de Tejada (1)  ·  Cairo University (1)  ·  Centre Hospitalier Régional Metz-Thionville (1)  ·  Centro Hospitalar De São João, E.P.E. (1)  ·  Columbia University (1)  ·  Consorci Sanitari de Terrassa (1)  ·  Etlik Zubeyde Hanım Women's Health Care, Training and Research Hospital (1)  ·  HUDDA Ahmad (1)  ·  Hayat Abad Medical Complex, Peshawar (1)  ·  Henry Ford Health System (1)  ·  Hospital Miguel Servet (1)

Countries

United States (20)  ·  France (6)  ·  Israel (3)  ·  Italy (3)  ·  Japan (3)  ·  Pakistan (3)  ·  Canada (2)  ·  China (2)  ·  Turkey (Türkiye) (2)  ·  Austria (1)  ·  Denmark (1)  ·  Egypt (1)  ·  Estonia (1)  ·  Finland (1)  ·  Honduras (1)

Top investigators

Helen Colquhoun, MD (2)  ·  Leena Rahkonen, MD, PhD, Associate professor (2)  ·  Anita Harding, MBChB (1)  ·  Anne ML Berndl, MD MSc (1)  ·  Arlen Jarrett, MD (1)  ·  Britt-Ingjerd Nesheim, MD, PhD (1)  ·  Daniel W Skupski, MD (1)  ·  Deborah Wing, MD (1)  ·  Denis Gallot (1)  ·  Duk Soo Bae, M.D. (1)  ·  Feng Lin (1)  ·  Franck Perrotin, MD-PhD (1)

Results publications

PMID 36996264, PMID 32852803, PMID 11704164, PMID 16034897, PMID 17077234, PMID 17766600, PMID 18515515, PMID 18827122, PMID 19622986, PMID 20466294, PMID 20542898, PMID 20567177, PMID 21225563, PMID 21343755, PMID 21924396, PMID 21959071, PMID 23685080, PMID 23743471, PMID 23857539, PMID 24222365, PMID 25712577, PMID 25758619, PMID 28050900, PMID 28125096, PMID 28204882, PMID 28334562, PMID 29211328, PMID 29215519, PMID 29981523, PMID 30098985, PMID 30723912, PMID 31623014, PMID 31915047, PMID 32080050, PMID 33094550, PMID 34061352, PMID 34109770, PMID 36972835, PMID 37068892, PMID 37807591, PMID 40054666, PMID 41592839

NIH funding

2015 (1)