8 completed, 2 unknown, 2 withdrawn, 1 recruiting. 14 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 14 | Completed 8, Unknown 2, Withdrawn 2, Recruiting 1, Terminated 1 |
Follow Cervical Ripening: new trials by email Literature Review of Cervical Ripening trials Research Report on Cervical Ripening
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Oxytocin vs Prostaglandins for Labor Induction of Women With an Unfavorable Cervix After 24h of Cervical Ripening Prostaglandins, Oxytocin - Cervical Ripening, Unfavorable Cervix | Phase 3 | Recruiting | University Hospital, Tours | 1494 | 2021-09-28 | 2026-07-27 |
| A Randomised Trial Investigating the Efficacy and Safety of a Vaginal Insert in Pregnant Women at Term Dinoprostone, Placebo - Cervical Ripening | Phase 3 | Completed | Ferring Pharmaceuticals | 114 | 2017-04-03 | 2020-11-03 |
| An Open-label Trial Investigating the Efficacy and Safety of a Vaginal Insert in Pregnant Women at Term Dinoprostone - Cervical Ripening | Phase 3 | Completed | Ferring Pharmaceuticals | 68 | 2017-02-22 | 2021-04-09 |
| Is There an Interest in Repeating the Vaginal Administration of Dinoprostone (Propess®), to Promote Induction of Labor of Pregnant Women at Term? Dinoprostone, Oxytocine - Cervical Ripening, Pregnancy | Phase 3 | Terminated | University Hospital, Limoges | 160 | 2016-12-01 | 2024-08-28 |
| Study of the Effectiveness of Cervical Ripening Balloon With and Without Oxytocin Oxytocin - Cervical Ripening, Induction of Labor | Phase 3 | Completed | University Hospitals Cleveland Medical Center | 180 | 2014-11-01 | 2022-05-04 |
| Induction of Labor in Oligohydramnios double balloon catheter, prostaglandins E2 - Cervical Ripening | Phase 3 | Unknown | Meir Medical Center | 100 | 2012-06-01 | 2012-03-23 |
| Safety and Efficacy Study of Vaginal Misoprostol for Cervical Ripening and Induction of Labor Placebo, Misoprostol vaginal Tablet 25 mcg - Cervical Ripening, Induction of Labor | Phase 3 | Completed | Regenex Pharmaceutical, China | 225 | 2012-03-01 | 2013-11-25 |
| Vaginal Misoprostol for Cervical Ripening Prior to Endometrial Biopsy Misoprostol, Placebo - Menorrhagia, Endometrial Biopsy | Phase 3 | Withdrawn | University of Saskatchewan | 2011-09-01 | 2012-08-14 | |
| Efficacy & Safety Study Comparing Misoprostol Vaginal Insert (MVI) Versus Dinoprostone Vaginal Insert (DVI) for Reducing Time to Vaginal Delivery MVI 200, Dinoprostone Vaginal Insert (DVI) - Reducing Time to Vaginal Delivery, Cervical Ripening | Phase 3 | Completed | Ferring Pharmaceuticals | 1358 | 2010-09-01 | 2014-05-01 |
| Cervical Priming With Misoprostol Prior to Operative Hysteroscopy Misoprostol - Cervical Ripening | Phase 3 | Completed | Samsung Medical Center | 141 | 2008-07-01 | 2009-12-02 |
| Misoprostol For Nulliparous Women Before Hysteroscopy misoprostol, oral misoprostol - Cervical Ripening | Phase 3 | Unknown | Wenzhou Medical University | 120 | 2008-05-01 | 2010-07-08 |
| Hysteroscopy After Pretreatment With Misoprostol and Estradiol Trial Misoprostol, Placebo - Cervical Ripening | Phase 3 | Completed | Ullevaal University Hospital | 100 | 2008-01-01 | 2009-05-25 |
| Safety/Efficacy Study Comparing the Misoprostol Vaginal Insert to Cervidil for Cervical Ripening and Induction of Labor Misoprostol vaginal insert 100 mcg, Misoprostol vaginal insert 50 mcg, Dinoprostone vaginal insert (Cervidil) - Cervical Ripening, Labor, Induced | Phase 3 | Completed | Ferring Pharmaceuticals | 1308 | 2006-04-01 | 2012-06-25 |
| Cervical Ripening Before Induction of Labour at Term: a Randomised Comparison of Prostin vs Propess Prostaglandin E2 - Cervical Ripening, Labor, Induced | Phase 3 | Withdrawn | Institut National de la Santé Et de la Recherche Médicale, France | 2002-01-01 | 2025-09-04 |
Dilatation, Pathologic (1) · Menorrhagia (1)
Pathological Conditions, Signs and Symptoms (2) · Female Urogenital Diseases (1) · Female Urogenital Diseases and Pregnancy Complications (1) · Genital Diseases (1) · Genital Diseases, Female (1) · Hemorrhage (1) · Menstruation Disturbances (1) · Pathologic Processes (1) · Pathological Conditions, Anatomical (1) · Urogenital Diseases (1) · Uterine Diseases (1) · Uterine Hemorrhage (1)
Dinoprostone (6) · Misoprostol (4) · Oxytocin (2) · Prostaglandins (1)
Ferring Pharmaceuticals (4) · Institut National de la Santé Et de la Recherche Médicale, France (1) · Meir Medical Center (1) · Regenex Pharmaceutical, China (1) · Samsung Medical Center (1) · Ullevaal University Hospital (1) · University Hospital, Limoges (1) · University Hospital, Tours (1) · University Hospitals Cleveland Medical Center (1) · University of Saskatchewan (1) · Wenzhou Medical University (1)
France (3) · United States (3) · Canada (2) · China (2) · Japan (2) · Israel (1) · Norway (1) · South Korea (1)
Anita Harding, MBChB (1) · Britt-Ingjerd Nesheim, MD, PhD (1) · Duk Soo Bae, M.D. (1) · Feng Lin (1) · Franck Perrotin, MD-PhD (1) · Helen Colquhoun, MD (1) · Marilyn Davidson, FRCSC (1) · Roger Pierson, PhD (1) · Thirza Smith, MD, FRCS (1) · Wen Di, MD (1)
PMID 18827122, PMID 19622986, PMID 20542898, PMID 21225563, PMID 23857539, PMID 25758619, PMID 28125096, PMID 31915047, PMID 33094550, PMID 37068892