9 completed, 2 terminated, 1 recruiting. 5 Phase 3, 2 Not applicable, 2 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 5 | Completed 3, Recruiting 1, Terminated 1 |
| Not applicable | 2 | Completed 2 |
| Phase 2 | 2 | Completed 2 |
| Phase 4 | 1 | Completed 1 |
Follow Prostaglandins: new trials by email Literature Review of Prostaglandins trials Research Report on Prostaglandins
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Oxytocin vs Prostaglandins for Labor Induction of Women With an Unfavorable Cervix After 24h of Cervical Ripening Prostaglandins, Oxytocin - Cervical Ripening, Unfavorable Cervix | Phase 3 | Recruiting | University Hospital, Tours | 1494 | 2021-09-28 | 2026-07-27 |
| Mechanical Dilation of the Cervix in a Scarred Uterus Cervical balloon, Prostaglandins - Pregnancy Related, Labor Complication | Not applicable | Completed | Ministry of Health, Singapore | 44 | 2019-08-29 | 2025-12-15 |
| RCT to Investigate if Prostaglandin Analogue Drops Increase the Risk of Cystoid Macular Oedema After Cataract Surgery. Prostaglandins - Open Angle Glaucoma and Cataract | Phase 2 | Completed | Julie Dawson | 56 | 2016-12-07 | 2020-10-08 |
| Non-inferiority of PRO-067 Ophthalmic Solution vs GAAP Ofteno® in Glaucoma or Ocular Hypertension PRO-067, GAAP Ofteno® - Primary Open Angle Glaucoma, Ocular Hypertension | Phase 3 | Terminated | Laboratorios Sophia S.A de C.V. | 116 | 2015-09-01 | 2024-07-05 |
| Treatment of Digital Ulcers in Korean Patients With Systemic Sclerosis: a Prospective Cohort Study Calcium Channel Blockers, Phosphodiesterase Inhibitors, Endothelin receptor blocker - Raynaud Disease, Systemic Sclerosis | Terminated | Seoul National University Hospital | 71 | 2015-01-01 | 2020-11-10 | |
| Combating Maternal Mortality in Uganda: An Assessment of the Role of Misoprostol in Prevention of Post-Partum Hemorrhage Misoprostol - Post Partum Hemorrhage | Phase 3 | Completed | Mbarara University of Science and Technology | 1140 | 2012-11-01 | 2014-09-08 |
| Trusopt and Cosopt; Ocular Perfusion Pressure and Blood Flow: New Long-term Prospective Data (Cosopt®, prostaglandin) - Glaucoma | Completed | Indiana University | 56 | 2010-06-01 | 2014-01-22 | |
| Efficacy and Safety Assessment of T2345 in Ocular Hypertensive or Glaucomatous Patients T2345, Prostaglandin - Glaucoma | Phase 3 | Completed | Laboratoires Thea | 404 | 2009-09-01 | 2015-01-22 |
| Exploratory Study Comparing Signs and Symptoms in Patients With Ocular Hypertension or Glaucoma Using Xalatan R® or Travatan Z® Xalatan, Travatan Z - Dry Eye Disease | Phase 4 | Completed | Ophthalmic Consultants of Long Island | 56 | 2008-10-01 | 2011-07-21 |
| Pharmacokinetics, Efficacy and Safety Assessment of T2345 Compared With Active Comparator in Newly Diagnosed Patients With Open-angle Glaucoma or Ocular Hypertension T2345, Prostaglandin - Primary Open Angle Glaucoma | Phase 2 | Completed | Laboratoires Thea | 30 | 2008-06-01 | 2024-02-07 |
| Misoprostol With Intrauterine Device Insertion Misoprostol, Magnesium Oxide - Contraception | Not applicable | Completed | Oregon Health and Science University | 40 | 2007-06-01 | 2013-03-15 |
| A Study to Evaluate the Effectiveness of Cosopt® as First Line Therapy (MK-0507A-153) dorzolamide hydrochloride (+) timolol maleate, Comparator: dorzolamide HCl/timolol maleate + prostaglandin - Glaucoma, Ocular Hypertension | Phase 3 | Completed | Merck Sharp & Dohme LLC | 170 | 2006-05-31 | 2017-04-04 |
Glaucoma (5) · Glaucoma, Open-Angle (4) · Ocular Hypertension (3) · Agnosia (1) · Cataract (1) · Disease Progression (1) · Dry Eye Syndromes (1) · Hyperemia (1) · Macular Edema (1) · Obstetric Labor Complications (1) · Postpartum Hemorrhage (1) · Raynaud Disease (1) · Scleroderma, Systemic (1) · digital ulcers (1)
Laboratoires Thea (2) · Indiana University (1) · Julie Dawson (1) · Laboratorios Sophia S.A de C.V. (1) · Mbarara University of Science and Technology (1) · Merck Sharp & Dohme LLC (1) · Ministry of Health, Singapore (1) · Ophthalmic Consultants of Long Island (1) · Oregon Health and Science University (1) · Seoul National University Hospital (1) · University Hospital, Tours (1)
United States (3) · France (2) · Mexico (1) · Singapore (1) · South Korea (1) · Uganda (1) · United Kingdom (1)
Alison Edelman, M.D., M.P.H (1) · Alon Harris, PhD (1) · Amon Agaba, PhD (1) · Barbara Burger, R.N. (1) · Marguerite McDonald, M.D. (1) · Nuwan Niyadurupola, Consultant (1)
PMID 20874498, PMID 21527040, PMID 25369200, PMID 27310103, PMID 31699720, PMID 37068892
2009 (1), 2018 (1)