4 completed, 2 recruiting, 1 not yet recruiting, 1 unknown. 3 Not applicable, 2 Phase 4, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Completed 1, Not yet recruiting 1, Recruiting 1 |
| Phase 4 | 2 | Completed 2 |
| Phase 2 | 1 | Recruiting 1 |
| Phase 3 | 1 | Completed 1 |
Follow Central Diabetes Insipidus: new trials by email Literature Review of Central Diabetes Insipidus trials Research Report on Central Diabetes Insipidus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Intranasal Oxytocin on Sexual Well-Being in Patients With Arginine Vasopressin Deficiency and Healthy Controls Oxytocin nasal spray, Placebo - Arginine Vasopressin Deficiency, Central Diabetes Insipidus | Phase 2 | Recruiting | University Hospital, Basel, Switzerland | 42 | 2025-07-01 | 2025-10-03 |
| Arginin-stimulated Copeptin in Polyuria-polydipsia Syndrome in Children Measure of Basal Copeptin level, Measure of arginine-stimulated copeptin, IRM - Primary Polydipsia, Central Diabetes Insipidus | Not applicable | Not yet recruiting | Assistance Publique Hopitaux De Marseille | 155 | 2025-03-01 | 2025-02-13 |
| Plasma Oxytocin Changes in Response to Low-dose MDMA vs. Placebo in Patients With Arginine Vasopressin Deficiency and Healthy Controls MDMA, Placebo - Central Diabetes Insipidus | Not applicable | Recruiting | University Hospital, Basel, Switzerland | 24 | 2025-01-27 | 2025-02-19 |
| Identification and Clinical Relevance of an Oxytocin Deficient State (Melatonin Study) Melatonin - Oxytocin Deficiency, Hypopituitarism | Not applicable | Completed | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | 40 | 2022-04-01 | 2024-04-09 |
| Identification and Clinical Relevance of an Oxytocin Deficient State (GLP1 Study) Experimental: GLP1-RA (exenatide) administration, Control: Placebo administration - Hypopituitarism, Central Diabetes Insipidus | Phase 4 | Completed | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | 42 | 2021-09-13 | 2026-01-20 |
| Identification and Clinical Relevance of an Oxytocin Deficient State (CRH Study) Experimental: CRH administration, Control: Placebo administration - Hypopituitarism, Central Diabetes Insipidus | Phase 4 | Completed | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | 52 | 2021-07-06 | 2024-04-03 |
| Seoul National University Pituitary Disease Cohort Study Dynamic hormone study and Magnetic resonance imaging - Pituitary Disease, Pituitary Incidentaloma | Unknown | Seoul National University Hospital | 1600 | 2015-03-15 | 2020-03-18 | |
| A Study of Minirin Melt in Japanese Patients With Central Diabetes Insipidus (CDI). Desmopressin Oral Melt, Desmopressin intranasal - Central Diabetes Insipidus | Phase 3 | Completed | Ferring Pharmaceuticals | 20 | 2011-01-01 | 2012-08-13 |
Diabetes Insipidus, Neurogenic (8) · Hypopituitarism (3) · Pituitary Diseases (3) · Social Isolation (3) · Combined Pituitary Hormone Deficiency (2) · Hypothalamic Diseases (2) · Mental Disorders (2) · Acromegaly (1) · Diabetes Insipidus (1) · Diabetes Insipidus, Nephrogenic (1) · Diabetes Mellitus (1) · Pituitary ACTH Hypersecretion (1) · Pituitary Neoplasms (1) · Polydipsia, Psychogenic (1) · Prolactinoma (1)
Endocrine System Diseases (8) · Female Urogenital Diseases (8) · Female Urogenital Diseases and Pregnancy Complications (8) · Kidney Diseases (8) · Male Urogenital Diseases (8) · Urogenital Diseases (8) · Urologic Diseases (8) · Diabetes Insipidus (7) · Pituitary Diseases (5) · Behavior (4) · Brain Diseases (4) · Central Nervous System Diseases (4) · Nervous System Diseases (4) · Social Behavior (3) · Hypothalamic Diseases (2)
Deamino Arginine Vasopressin (1) · Exenatide (1) · Magnetic Resonance Spectroscopy (1) · Melatonin (1) · N-Methyl-3,4-methylenedioxyamphetamine (1) · Organization and Administration (1) · Oxytocin (1) · Sodium Chloride (1)
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau (3) · University Hospital, Basel, Switzerland (2) · Assistance Publique Hopitaux De Marseille (1) · Ferring Pharmaceuticals (1) · Seoul National University Hospital (1)
Spain (3) · Switzerland (2) · France (1) · Japan (1) · South Korea (1)
Anna Aulinas, MD PhD (2) · Jung Hee Kim, M.D (1) · Mirjam Christ-Crain, Prof. (1) · Mirjam Christ-Crain, Prof. MD (1)