114 completed. 114 Phase 2, 30 Phase 1, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 114 | Completed 114 |
| Phase 1 | 30 | Completed 30 |
| Phase 3 | 2 | Completed 2 |
Follow Carcinogenesis: new trials by email Literature Review of Carcinogenesis trials Research Report on Carcinogenesis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Decitabine, Venetoclax, and Ponatinib for the Treatment of Philadelphia Chromosome-Positive Acute Myeloid Leukemia or Myeloid Blast Phase or Accelerated Phase Chronic Myelogenous Leukemia Decitabine, Ponatinib, Venetoclax - Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Myeloid Leukemia | Phase 2 | Completed | M.D. Anderson Cancer Center | 20 | 2020-05-17 | 2026-06-05 |
| Phase I/II Study of Bosutinib in Combination With Inotuzumab Ozogamicin in CD22-positive PC Positive ALL and CML Bosutinib, Inotuzumab Ozogamicin - B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1, Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Phase 1 / Phase 2 | Completed | M.D. Anderson Cancer Center | 22 | 2015-04-16 | 2023-07-17 |
| Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors in Preventing GVHD Allogeneic Hematopoietic Stem Cell Transplantation, Cyclophosphamide, Fludarabine Phosphate - Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Biphenotypic Leukemia | Phase 2 | Completed | Fred Hutchinson Cancer Center | 84 | 2015-03-23 | 2026-06-01 |
| Natural Killer Cells Before and After Donor Stem Cell Transplant in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelogenous Leukemia Allogeneic Hematopoietic Stem Cell Transplantation, Bone Marrow Transplantation, Cyclophosphamide - Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Phase 1 / Phase 2 | Completed | M.D. Anderson Cancer Center | 54 | 2014-04-22 | 2024-01-24 |
| Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts in Preventing GVHD in Children Allogeneic Hematopoietic Stem Cell Transplantation, Fludarabine Phosphate, Laboratory Biomarker Analysis - Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Biphenotypic Leukemia | Phase 2 | Completed | Fred Hutchinson Cancer Center | 20 | 2014-04-10 | 2024-03-12 |
| Phase I/II Study of Nilotinib/Ruxolitinb Therapy for TKI Resistant Ph-Leukemia Nilotinib, Ruxolitinib - Chronic Phase Chronic Myeloid Leukemia, Accelerated Phase Chronic Myeloid Leukemia | Phase 1 / Phase 2 | Completed | University Health Network, Toronto | 4 | 2013-08-01 | 2020-11-02 |
| Donor Natural Killer Cells and Donor Stem Cell Transplant in Treating Patients With High Risk Myeloid Malignancies Aldesleukin, Allogeneic CD56-positive CD3-negative Natural Killer Cells, Allogeneic Hematopoietic Stem Cell Transplantation - Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Erythroid Leukemia | Phase 1 / Phase 2 | Completed | M.D. Anderson Cancer Center | 63 | 2013-06-11 | 2023-11-07 |
| Donor T Cells After Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies therapeutic allogeneic lymphocytes, laboratory biomarker analysis - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Phase 2 | Completed | University of Chicago | 77 | 2013-04-04 | 2019-08-07 |
| Eltrombopag Olamine in Treating Thrombocytopenia in Patients With Chronic Myeloid Leukemia or Myelofibrosis Receiving Tyrosine Kinase Therapy Eltrombopag Olamine - Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Phase 2 / Phase 3 | Completed | M.D. Anderson Cancer Center | 21 | 2012-01-13 | 2023-09-26 |
| Cyclophosphamide for Prevention of Graft-Versus-Host Disease After Allogeneic Peripheral Blood Stem Cell Transplantation in Patients With Hematological Malignancies cyclophosphamide, cyclosporine, peripheral blood stem cell transplantation - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Fred Hutchinson Cancer Center | 43 | 2011-09-01 | 2017-05-19 |
| Reduced-Intensity Busulfan and Fludarabine With or Without Antithymocyte Globulin Followed by Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Other Disease anti-thymocyte globulin, sargramostim, therapeutic allogeneic lymphocytes - Chronic Myeloproliferative Disorders, Leukemia | Phase 2 | Completed | UNC Lineberger Comprehensive Cancer Center | 71 | 2011-01-07 | 2017-05-30 |
| Safety Study of Adjuvant Vaccine to Treat Melanoma Patients NY-ESO-1 protein; Poly-ICLC; Montanide - Melanoma | Phase 1 / Phase 2 | Completed | Nina Bhardwaj | 34 | 2010-09-01 | 2018-02-13 |
| Fludarabine and Cytarabine in Acute Myelogenous Leukemia (AML) and High-Risk Myelodysplastic Syndrome (MDS) Cytarabine, Fludarabine - Leukemia, AML | Phase 2 | Completed | M.D. Anderson Cancer Center | 151 | 2009-11-01 | 2016-03-15 |
| CLAG Gleevec in Relapsed or Refractory Acute Myeloid Leukemia (AML) CLAG Regimen, Gleevec® - Leukemia | Phase 2 | Completed | H. Lee Moffitt Cancer Center and Research Institute | 38 | 2009-08-01 | 2014-06-27 |
| Treosulfan, Fludarabine Phosphate, and Total-Body Irradiation Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Myelodysplastic Syndrome, Acute Lymphoblastic Leukemia treosulfan, fludarabine phosphate, total-body irradiation - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Fred Hutchinson Cancer Center | 96 | 2009-02-01 | 2021-06-22 |
| Donor Natural Killer Cells After Donor Stem Cell Transplant in Treating Patients With Advanced Cancer donor natural killer cell infusion - Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders | Phase 1 / Phase 2 | Completed | Asan Medical Center | 47 | 2009-01-01 | 2013-02-20 |
| Nilotinib and Imatinib Mesylate After Donor Stem Cell Transplant in Treating Patients With ALL or CML nilotinib, imatinib mesylate, pharmacological study - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 1 / Phase 2 | Completed | Fred Hutchinson Cancer Center | 40 | 2008-08-14 | 2017-08-10 |
| Ondansetron in Preventing Nausea and Vomiting in Patients Undergoing Stem Cell Transplant ondansetron, survey administration, management of therapy complications - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Fred Hutchinson Cancer Center | 49 | 2008-08-08 | 2017-05-23 |
| Donor Stem Cell Transplant After Busulfan, Fludarabine, and Antithymocyte Globulin in Treating Patients With Hematologic Cancer or Myelodysplastic Syndrome nonmyeloablative allogeneic hematopoietic stem cell transplantation, peripheral blood stem cell transplantation - Leukemia, Myelodysplastic Syndromes | Phase 2 | Completed | Asan Medical Center | 54 | 2008-04-01 | 2012-07-17 |
| Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies double-unit umbilical cord blood transplantation, cytogenetic analysis, bone marrow aspiration - Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Case Comprehensive Cancer Center | 14 | 2007-09-01 | 2019-01-23 |
Showing 20 of 114. Sign in to see all of them.
Blast Crisis (113) · Leukemia, Myeloid, Accelerated Phase (79) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (78) · Leukemia, Myeloid, Acute (74) · Leukemia (73) · Leukemia, Myeloid, Chronic-Phase (61) · Myelodysplastic Syndromes (57) · Burkitt Lymphoma (52) · Leukemia, Lymphocytic, Chronic, B-Cell (50) · Lymphoma, Non-Hodgkin (48) · Lymphoma, Follicular (47) · Lymphoma, Large-Cell, Immunoblastic (47) · Lymphoma, Mantle-Cell (47) · Lymphoma, B-Cell, Marginal Zone (46) · Lymphoma, Large B-Cell, Diffuse (46)
Neoplasms by Histologic Type (114) · Neoplastic Processes (114) · Pathologic Processes (114) · Pathological Conditions, Signs and Symptoms (114) · Bone Marrow Diseases (113) · Cell Transformation, Neoplastic (113) · Chronic Disease (113) · Disease Attributes (113) · Hemic and Lymphatic Diseases (113) · Hematologic Diseases (112) · Leukemia, Myeloid (112) · Neoplasms (109) · Immune System Diseases (84) · Immunoproliferative Disorders (82)
Peripheral Blood Stem Cell Transplantation (31) · Cyclophosphamide (30) · fludarabine phosphate (28) · Busulfan (26) · Methotrexate (21) · Tacrolimus (21) · Cyclosporine (17) · Antilymphocyte Serum (16) · Mycophenolic Acid (15) · Cytarabine (14) · Filgrastim (14) · Radiotherapy (14) · Whole-Body Irradiation (14) · Imatinib Mesylate (13) · Methylprednisolone (11)
Fred Hutchinson Cancer Center (28) · M.D. Anderson Cancer Center (11) · Memorial Sloan Kettering Cancer Center (10) · Case Comprehensive Cancer Center (7) · National Cancer Institute (NCI) (6) · Roswell Park Cancer Institute (4) · Asan Medical Center (3) · UNC Lineberger Comprehensive Cancer Center (3) · University of Maryland, Baltimore (3) · Bristol-Myers Squibb (2) · Cancer Treatment Centers of America (2) · Children's Oncology Group (2) · H. Lee Moffitt Cancer Center and Research Institute (2) · Jonsson Comprehensive Cancer Center (2) · Masonic Cancer Center, University of Minnesota (2)
United States (99) · Canada (8) · Italy (7) · France (5) · Germany (5) · South Korea (4) · Switzerland (3) · Australia (2) · Belgium (2) · Denmark (2) · Austria (1) · Finland (1) · Israel (1) · Netherlands (1) · Norway (1)
Claudio Anasetti, MD (3) · Kyoo H. Lee, MD (3) · Philip L. McCarthy, MD (3) · Sergio Giralt, MD (3) · Ann E. Woolfrey, MD (2) · Brenda Sandmaier (2) · Brenda W. Cooper, MD (2) · Claudio G. Brunstein, MD, PhD (2) · Marie Bleakley (2) · Paul Carpenter, MD (2) · Thomas C. Shea, MD (2) · Thomas J. Walsh, MD (2) · Albert von Rohr, MD (1) · Anastasios Raptis, MD (1)
PMID 32499241, PMID 35007144, PMID 17910637, PMID 18327587, PMID 18769450, PMID 18838477, PMID 18989154, PMID 18997171, PMID 19179301, PMID 19286996, PMID 19706886, PMID 19841031, PMID 1994541, PMID 20124511, PMID 20466853, PMID 20858843, PMID 21403127, PMID 21508120, PMID 21523798, PMID 21715313, PMID 22002488, PMID 22430088, PMID 24362550, PMID 25085357, PMID 26210442, PMID 26764356, PMID 34312462, PMID 39303729, PMID 7632970, PMID 8417795
P30CA015704 (7), P30CA043703 (6), P01CA018029 (4), P01CA078902 (3), P30CA016672 (3), N01CM62202 (2), P01HL036444 (2), P30CA006973 (2), P30CA016086 (2), R01HL121568 (2), 2005 (1), K23CA154532 (1), P01CA015396 (1), P01CA023766 (1), P01CA049639 (1)