31 completed, 7 recruiting, 7 unknown, 5 terminated. 19 Not applicable, 15 Phase 2, 6 Phase 1, 5 Phase 3, 1 Early Phase 1.
Follow Cancer of the Prostate: new trials by email Literature Review of Cancer of the Prostate trials Research Report on Cancer of the Prostate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Low-Count Quantitative SPECT for Men Treated With Radium-223 Low-count quantitative single-photon emission computed tomography imaging - Prostate Cancer, Cancer of the Prostate | Not applicable | Recruiting | Washington University School of Medicine | 38 | 2026-11-01 | 2026-10-15 |
| This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve. Mevrometostat, Placebo, Enzalutamide - Metastatic Castration Sensitive Prostate Cancer (mCSPC), Hormone Sensitive Prostate Cancer | Phase 3 | Recruiting | Pfizer | 1000 | 2025-09-28 | 2026-10-14 |
| Investigation of Impact of AI on Prostate Cancer Workflow AI - Prostate Cancer, Prostatic Neoplasm | Not applicable | Recruiting | Case Comprehensive Cancer Center | 150 | 2025-09-09 | 2026-09-15 |
| Impact of an Electronic Health Record Maintenance Alert on PSA Screening Rates in a 10-Hospital Integrated Health System Annual PSA Health Maintenance Reminder - Prostate Cancer, Cancer of the Prostate | Not applicable | Recruiting | Washington University School of Medicine | 40000 | 2025-08-11 | 2026-08-19 |
| A SMART Design to Optimize the Delivery of TEMPO for Men With Prostate Cancer and Their Caregivers TEMPO, Active Monitoring dyads' anxiety - Cancer of the Prostate, Anxiety | Not applicable | Recruiting | St. Mary's Research Center, Canada | 376 | 2025-08-01 | 2026-06-11 |
| A Study to Learn About Two Medicines (Apalutamide and Enzalutamide) in People With Metastatic Castration-sensitive Prostate Cancer (mCSPC) Enzalutamide, Apalutamide - Metastatic Castration Sensitive Prostate Cancer (mCSPC), Cancer of the Prostate | Completed | Pfizer | 1300 | 2025-07-21 | 2025-12-08 | |
| Adaptive Stereotactic Body Radiation Therapy to the Prostate and Pelvic Nodes With Simultaneous Integrated Boost to the MR-detected Nodule for Patients With High-risk and Unfavorable Intermediate-risk Prostate Cancer Ethos Varian treatment system, Adaptive stereotactic body radiotherapy, Androgen deprivation therapy - Prostate Cancer, Cancer of the Prostate | Not applicable | Active not recruiting | Washington University School of Medicine | 28 | 2023-01-18 | 2026-07-02 |
| Study of NUV-422 in Combination With Enzalutamide in Patients With mCRPC NUV-422, Enzalutamide - Prostate Cancer, Prostatic Cancer | Phase 1 / Phase 2 | Withdrawn | Nuvation Bio Inc. | 2022-09-01 | 2022-08-05 | |
| NUV-868 as Monotherapy and in Combination With Olaparib or Enzalutamide in Adult Patients With Advanced Solid Tumors NUV-868, Olaparib, Enzalutamide - Advanced Solid Tumor, Ovarian Cancer | Phase 1 | Terminated | Nuvation Bio Inc. | 82 | 2022-03-29 | 2025-11-06 |
| Study of NUV-422 in Adults With Recurrent or Refractory High-grade Gliomas and Solid Tumors NUV-422 - Glioma, Glioma, Malignant | Phase 1 | Terminated | Nuvation Bio Inc. | 74 | 2020-12-08 | 2023-07-14 |
| MRI/Ultrasound Fusion Guided Laser Ablation of Prostate Cancer Image Fusion (MR/US) Software Registration Guided Laser Ablation of Prostate Cancer - Neoplasms Prostate, Cancer of the Prostate | Recruiting | Urological Research Network, LLC | 5000 | 2020-11-15 | 2023-01-26 | |
| I-131-1095 Radioligand Plus Enzalutamide vs Enzalutamide for mCRPC That Progressed During Abiraterone (ARROW). I-131-1095, Enzalutamide - Metastatic Prostate Cancer, Castration-resistant Prostate Cancer | Phase 2 | Completed | Progenics Pharmaceuticals, Inc. | 120 | 2019-05-30 | 2025-10-14 |
| High Intensity Interval Training (HIIT) for Patients With Cancer-related Lymphedema in the Lower Limbs First exercise session + compression, First exercise session - compression - Lymphedema of Leg, Cancer of Cervix | Not applicable | Completed | Herlev and Gentofte Hospital | 20 | 2018-09-06 | 2018-11-15 |
| Proton Boost in Prostate Cancer Proton Boost - Cancer of the Prostate | Not applicable | Active not recruiting | University of Cincinnati | 10 | 2018-04-16 | 2025-05-31 |
| A Trial of 177Lu-PSMA617 Theranostic Versus Cabazitaxel in Progressive Metastatic Castration Resistant Prostate Cancer 177Lu-PSMA617, Cabazitaxel - Cancer of the Prostate, Metastatic Cancer | Phase 2 | Completed | Australian and New Zealand Urogenital and Prostate Cancer Trials Group | 201 | 2018-01-29 | 2022-06-13 |
| Gadoxetate Sodium Enhanced MRI as a Biomarker for Aggressive Prostate Cancer Gadoxetate Sodium - Cancer of the Prostate, Castration-resistant Prostate Cancer | Early Phase 1 | Unknown | University of Cincinnati | 50 | 2018-01-02 | 2019-05-23 |
| Decision Impact Trial of the ExoDx Prostate (IntelliScore) ExoDx Prostate (IntelliScore) - Cancer of the Prostate | Not applicable | Unknown | Exosome Diagnostics, Inc. | 1000 | 2017-07-19 | 2022-05-06 |
| Prostate Cancer Survivors and Exercise and Behavioral Counseling Supervised Physical Activity Plus Behavioral Counseling, Supervised Physical Activity Plus Exercise Counseling - Physical Activity, Cancer of the Prostate | Phase 2 | Completed | University of Illinois at Urbana-Champaign | 27 | 2017-07-06 | 2019-12-20 |
| Neoadjuvant Apalutamide (ARN509) and Radical Prostatectomy in Treatment of Intermediate to High Risk Prostate Cancer Apalutamide - Cancer of the Prostate | Phase 2 | Completed | Singapore General Hospital | 30 | 2017-06-20 | 2020-03-19 |
| MR-simulation in Radiotherapy for Prostate Cancer MRI scan - Cancer of the PROSTATE | Not applicable | Unknown | Guy's and St Thomas' NHS Foundation Trust | 40 | 2017-03-01 | 2022-03-18 |
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Prostatic Neoplasms (55) · Neoplasms (4) · Motor Activity (3) · Prostatic Neoplasms, Castration-Resistant (3) · Recurrence (3) · Breast Neoplasms (2) · Cognitive Dysfunction (2) · Male Urogenital Diseases (2) · Ovarian Neoplasms (2) · Anxiety Disorders (1) · Endometrial Neoplasms (1) · Glioblastoma (1) · Glioma (1) · Melanoma (1) · Neoplasm Metastasis (1)
Genital Diseases (55) · Genital Diseases, Male (55) · Genital Neoplasms, Male (55) · Neoplasms by Site (55) · Prostatic Diseases (55) · Urogenital Diseases (55) · Urogenital Neoplasms (55) · Male Urogenital Diseases (53) · Neoplasms (51) · Pathologic Processes (4) · Pathological Conditions, Signs and Symptoms (4) · Behavior (3) · Disease Attributes (3) · Mental Disorders (3) · Skin Diseases (3)
enzalutamide (8) · Radiosurgery (4) · Cholecalciferol (2) · Lycopene (2) · Radiotherapy (2) · Selenium (2) · Tea (2) · Vitamin E (2) · apalutamide (2) · Androgen Antagonists (1) · Behavior Therapy (1) · Cyclophosphamide (1) · Leuprolide (1) · Magnetic Resonance Imaging (1) · Magnetic Resonance Spectroscopy (1)
Pfizer (4) · Washington University School of Medicine (4) · Nuvation Bio Inc. (3) · Accuray Incorporated (2) · CMX Research (2) · Exact Imaging (2) · University Health Network, Toronto (2) · University of Cincinnati (2) · Urological Research Network, LLC (2) · Alliance Foundation Trials, LLC. (1) · Asana BioSciences (1) · Assistance Publique - Hôpitaux de Paris (1) · Astellas Pharma Inc (1) · Australian and New Zealand Urogenital and Prostate Cancer Trials Group (1) · BHR Pharma, LLC (1)
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Isabel H Lopez, MD (2) · Neil Fleshner (2) · Robert Meier, MD (2) · Abhinav K Jha, Ph.D. (1) · Amit Bhatt, M.D., Ph.D. (1) · Anders Vinther, PT MSc PhD (1) · Andrei Purysko, MD (1) · Andrew Stubbs, PhD (1) · Art F Kramer, PhD (1) · Brendan D Curti, MD (1) · Carsten B Juhl, PT MPH PhD (1) · Christian Rothermundt, MD (1)
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R01EB031962 (1)