16 recruiting, 11 active not recruiting, 8 completed, 6 not yet recruiting. 23 Not applicable, 13 Phase 2, 5 Phase 3, 2 Phase 1, 1 Early Phase 1.
Follow Breast Cancer Stage III: new trials by email Literature Review of Breast Cancer Stage III trials Research Report on Breast Cancer Stage III
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Herbs & Supplements in Breast Cancer Usage, Impact, and Personalized Approaches for Diverse Populations No intervention - Breast Cancer, Breast Cancer Stage I | Not yet recruiting | Case Comprehensive Cancer Center | 240 | 2026-10-01 | 2026-08-28 | |
| Capecitabine in ER+/HER2-negative Breast Cancer Capecitabine - ER-positive, HER2-negative Breast Cancer, Breast Cancer Stage I | Phase 2 | Recruiting | University Health Network, Toronto | 15 | 2026-07-29 | 2026-08-18 |
| Effect of Meal Timing During Cancer Treatment in Patients in Alaska: A Randomized Clinical Trial Time-restricted eating, Questionnaire Administration, Biospecimen Collection - Rectal Cancer Stage II, Rectal Cancer Stage III | Not applicable | Recruiting | Fred Hutchinson Cancer Center | 100 | 2026-07-23 | 2026-07-29 |
| A Study of Meaning-Centered Therapy for Mexican Adults With Advanced Cancer Meaning-Centered Psychotherapy for Latinos /MCP-L - Breast Cancer, Prostate Cancer | Not applicable | Recruiting | Memorial Sloan Kettering Cancer Center | 300 | 2026-05-01 | 2026-08-03 |
| Pembrolizumab Adjuvant in Patients With Early-stage Triple Negative Breast Cancer With Residual Disease After Neoadjuvant Pembrolizumab Plus Chemotherapy Standard of care plus pembrolizumab, Standard of care (capecitabine or olaparib) - Triple Negative Breast Cancer (TNBC), Early Setting, Early Stage Triple-Negative Breast Carcinoma | Phase 3 | Not yet recruiting | The Netherlands Cancer Institute | 1000 | 2026-04-01 | 2026-03-20 |
| Neoadjuvant, SBRT With Intratumoural Pembrolizumab Followed by Neoadjuvant Chemotherapy in Breast Cancer Radiation, Pembrolizumab (KEYTRUDA®) - Breast Cancer, Breast Cancer Stage II | Phase 2 | Recruiting | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 40 | 2026-01-19 | 2026-02-11 |
| Study Assessing the Efficacy and Safety of cANnabidiol Oral Solution for Joint Pain of Adjuvant enDOcrine theRApy in Patients With Early Breast Cancer CBD oil, Placebo - Breast Cancer Stage I, Breast Cancer Stage II | Phase 3 | Not yet recruiting | Gustave Roussy, Cancer Campus, Grand Paris | 130 | 2025-12-01 | 2025-12-02 |
| CARE (Chemotherapy Alopecia REduction) Scalp Cooling by DigniCap - Breast Cancer, Breast - Female | Not applicable | Active not recruiting | George Washington University | 30 | 2025-09-24 | 2025-10-01 |
| Role of Triggering Receptor Expressed on Myeloid Cells (TREM-1) as a Novel Biomarker in Human Epidermal Growth Factor Receptor -2 (HER-2) Negative Breast Cancer: a Molecular and Clinical Study Breast Cancer Stage I, Breast Cancer Stage II | Not yet recruiting | Rahma Esam Salama Esawi | 1 | 2025-09-15 | 2025-04-30 | |
| Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline During Chemotherapy in Breast Cancer Memantine, Placebo medication, Exercise Intervention - Breast Cancer, Locally Advanced Breast Cancer | Phase 2 | Recruiting | UNC Lineberger Comprehensive Cancer Center | 90 | 2025-08-19 | 2026-05-06 |
| Evaluate BL-M17D1 in Patients w/HER2-Expressing/Mutant Advanced or Metastatic Solid Tumors BL-M17D1 - Breast Cancer Stage III, HER2-positive Metastatic Breast Cancer | Phase 1 | Terminated | SystImmune Inc. | 3 | 2025-04-10 | 2026-09-22 |
| Evaluation of the Efficacy of Biobran (Rice Bran Arabinoxylan) in Supporting Breast Cancer Chemotherapy Biobran supplementation - Breast Cancer Stages I, Breast Cancer Stages II | Not applicable | Recruiting | China Medical University Hospital | 96 | 2025-04-07 | 2026-03-31 |
| The Efficacy and Safety of CDK4/6 Inhibitors in Combination with Endocrine Therapy in the Neoadjuvant Treatment Ribociclib; abemaciclib; palbociclib; Dalpiciclib - Breast Cancer Stage III, Breast Cancer Stage II | Not applicable | Not yet recruiting | Hongmei Zheng, PhD | 40 | 2025-04-01 | 2025-03-17 |
| Abbreviated MBCT for Depression in Older Black or African American Breast Cancer Survivors MBCT - Breast Cancer, Breast Cancer Female | Not applicable | Active not recruiting | Case Comprehensive Cancer Center | 23 | 2025-03-21 | 2026-09-15 |
| A Study of Language Interpretation Solutions for People With Breast Cancer Remote Simultaneous Medical Interpreting/RSMI, Remote Consecutive Medical Interpreting/RCMI, Remote Consecutive Video Medical Interpreting/RCVI - Breast Cancer, Breast Cancer Stage II | Not applicable | Recruiting | Memorial Sloan Kettering Cancer Center | 700 | 2024-12-02 | 2026-09-25 |
| Improvement of Quality of Life Through Supportive Treatments for Hormone Therapy - Related Symptoms in Patients With Early Breast Cancer Duloxetine 60 MG, Furosemide 40 mg, Booklet for healthy behaviors - ER+ Breast Cancer, HER2-negative Breast Cancer | Phase 3 | Not yet recruiting | European Organisation for Research and Treatment of Cancer - EORTC | 399 | 2024-12-01 | 2024-11-05 |
| Predicting Response to Neoadjuvant Endocrine Therapy (Neo-PREDICT) Neoadjuvant endocrine therapy - Breast Cancer Stage I, Breast Cancer Stage II | Phase 2 | Recruiting | George Washington University | 90 | 2024-10-01 | 2026-03-03 |
| Tart Cherry Juice as a Dietary Supplement for the Prevention of Paclitaxel-Induced Neuropathy Tart Cherry Juice - Breast Cancer, Breast Cancer Stage I | Phase 2 | Recruiting | University of California, Davis | 86 | 2024-08-15 | 2026-03-04 |
| Optimizing Surgical Decisions in Young Adults With Breast Cancer CONSYDER decision aid - Breast Cancer Stage 0, Breast Cancer Stage I | Not applicable | Recruiting | Weill Medical College of Cornell University | 800 | 2024-03-13 | 2026-08-19 |
| Ultrahypofractionation and Normal Tissue Toxicity Accelerated Proton Beam Radiation Therapy (PBT), Accelerated Photon Radiation Therapy (XRT) - Breast Cancer, Breast Cancer Female | Not applicable | Active not recruiting | Massachusetts General Hospital | 60 | 2023-08-15 | 2025-11-13 |
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Breast Neoplasms (48) · Triple Negative Breast Neoplasms (5) · Breast Carcinoma In Situ (3) · Colorectal Neoplasms (2) · Motor Activity (2) · Ovarian Neoplasms (2) · Alopecia (1) · Breast Neoplasms, Male (1) · Carcinoma (1) · Carcinoma, Non-Small-Cell Lung (1) · Cardiotoxicity (1) · Cognitive Dysfunction (1) · Drug-Related Side Effects and Adverse Reactions (1) · Endometrial Neoplasms (1) · Fallopian Tube Neoplasms (1)
Breast Diseases (48) · Neoplasms by Site (48) · Skin Diseases (48) · Skin and Connective Tissue Diseases (48) · Neoplasms (47) · Digestive System Diseases (4) · Digestive System Neoplasms (4) · Gastrointestinal Diseases (4) · Gastrointestinal Neoplasms (4) · Neoplasms by Histologic Type (4) · Neoplasms, Glandular and Epithelial (4) · Pathological Conditions, Signs and Symptoms (4) · Behavior (3) · Carcinoma (3) · Carcinoma in Situ (3)
Capecitabine (3) · Letrozole (3) · Paclitaxel (3) · Trastuzumab (3) · pembrolizumab (3) · Carboplatin (2) · Docetaxel (2) · Gonadotropin-Releasing Hormone (2) · Tamoxifen (2) · palbociclib (2) · pertuzumab (2) · AC protocol (1) · Acupuncture Therapy (1) · Ado-Trastuzumab Emtansine (1) · Anastrozole (1)
Memorial Sloan Kettering Cancer Center (5) · Dana-Farber Cancer Institute (4) · Alliance for Clinical Trials in Oncology (2) · Case Comprehensive Cancer Center (2) · European Organisation for Research and Treatment of Cancer - EORTC (2) · George Washington University (2) · Massachusetts General Hospital (2) · University Health Network, Toronto (2) · University of Chicago (2) · Affiliated Hospital of Jiangnan University (1) · Baylor Breast Care Center (1) · China Medical University Hospital (1) · Covenant Health Cancer Center (1) · Emory University (1) · Fred Hutchinson Cancer Center (1)
United States (28) · Canada (4) · China (2) · France (2) · Nigeria (2) · South Korea (2) · Spain (2) · Belgium (1) · Czechia (1) · Egypt (1) · Germany (1) · Guam (1) · Italy (1) · Jordan (1) · Mexico (1)
Rachel Jimenez, MD (2) · Agnes Jager, MD, PhD (1) · Alina Markova, MD (1) · Ana Garrido-Castro, MD (1) · Anthony Yu, MD (1) · Barbara Andersen (1) · Christina M Dieli-Conwright, PhD (1) · Chunjing Yu (1) · Devika Jutagir, PhD (1) · Einsley Janowski, MD, PhD (1) · Elizabeth Stone, MD (1) · Eve Rodler, MD (1) · Francesca Gany, MD, MS (1) · Gabe Sonke, MD, PhD (1) · Haeyoung Kim, MD, PhD (1)
PMID 18487249, PMID 29285038, PMID 30762400, PMID 31144265, PMID 32628583, PMID 34275766, PMID 34956864, PMID 34989765, PMID 36396308, PMID 36696330, PMID 37923529, PMID 39320397, PMID 40382452, PMID 42128956
2023 (1), 2025 (1), K23AG086604 (1), P01CA261669 (1), P30CA138292 (1), P50CA285275 (1), R01CA256877 (1), UG1CA189823 (1)