8 completed, 5 recruiting, 2 not yet recruiting, 1 active not recruiting. 5 Not applicable, 3 Phase 1, 3 Phase 4, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Completed 3, Not yet recruiting 1, Recruiting 1 |
| Phase 1 | 3 | Completed 2, Recruiting 1 |
| Phase 4 | 3 | Completed 1, Not yet recruiting 1, Recruiting 1 |
| Phase 2 | 1 | Recruiting 1 |
Follow Axial Spondyloarthritis (AxSpA): new trials by email Literature Review of Axial Spondyloarthritis (AxSpA) trials Research Report on Axial Spondyloarthritis (AxSpA)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Pragmatic Trial of Interleukin-17 Inhibition Versus Janus Kinase Inhibition After Tumor Necrosis Factor-alpha Inhibitor Failure in Axial Spondyloarthritis Secukinumab (IL-17i ), Upadacitinib (JAKi) - Axial Spondyloarthritis (AxSpA) | Phase 4 | Not yet recruiting | The University of Texas Health Science Center, Houston | 40 | 2026-11-01 | 2026-10-14 |
| Postural Biofeedback and Exercise in Axial Spondyloarthritis Standard Exercise Program, Wearable Postural Biofeedback - Axial Spondyloarthritis (AxSpA), Ankylosing Spondylitis (AS) | Not applicable | Not yet recruiting | Istanbul University - Cerrahpasa | 38 | 2026-10-01 | 2026-08-21 |
| The REFLECT Study- Flares in axSpA Axial Spondyloarthritis (AxSpA), Axial Spondyloarthritis, Non-Radiographic | Active not recruiting | Royal United Hospitals Bath NHS Foundation Trust | 40 | 2026-06-01 | 2026-07-07 | |
| Multicenter Validation of the 2025 Classification Criteria for Axial Spondyloarthritis Diagnostic Assessment - Axial Spondyloarthritis (AxSpA), Spondyloarthritis (SpA) | Recruiting | Chinese PLA General Hospital | 247 | 2026-04-10 | 2026-07-24 | |
| REDO-JAK: Dose Reduction of Janus Kinase Inhibitors in Patients With Inflammatory Rheumatic Diseases JAKi dose reduction strategy, JAKi disease activity guided continuation of same dose strategy - Rheumatoid Arthritis (RA), Psoriatic Arthritis (PsA) | Phase 4 | Recruiting | Sint Maartenskliniek | 200 | 2025-09-15 | 2025-09-17 |
| EAST-1 (ERAP-inhibition in Axial Spondyloarthritis Trial - 1) Part A - Single Ascending Dose (SAD) in Healthy Human Volunteers, Part B - Multiple Ascending Dose (MAD) in participants with axSpA, Part C - Safety expansion cohort in participants with axSpA - Axial Spondyloarthritis (AxSpA) | Phase 1 / Phase 2 | Recruiting | Grey Wolf Therapeutics | 140 | 2025-07-28 | 2026-09-18 |
| Effects of Yoga Therapy in Rehabilitation Compared to Physiotherapy in Moderate Axial Spondyloarthritis (axSPA) Yogatherapy, Physiotherapy - Axial Spondyloarthritis (axSPA) | Not applicable | Recruiting | Assistance Publique - Hôpitaux de Paris | 72 | 2024-08-27 | 2025-10-01 |
| A LONGITUDINAL OBSERVATIONAL STUDY to EVALUATE the EFFICACY of MOVEMENT and IMPLEMENT CONCRETE MOVEMENT RECOMMENDATIONS with the HELP of MOBILITY TRACKING with SMARTWATCHES in SUBJECTS with AXIAL SPONDYLOARTHRITIS Smartwatch - Axial Spondyloarthritis, Axial Spondyloarthritis (AxSpA) | Recruiting | University of Bonn | 50 | 2024-04-01 | 2025-02-18 | |
| Retrospective Case-Control Study for Developing an Artificial Intelligence (AI) Tool for Lesion Detection Using Magnetic Resonance Imaging (MRI) and Clinical Variables for Early Diagnosis of Axial Spondyloarthritis (axSpA) Axial Spondyloarthritis (AxSpA) | Completed | Ángel Alberich Bayarri | 925 | 2023-02-19 | 2025-04-16 | |
| Effect of Aerobic Exercises on Axial Spondyloarthropathy Home Exercise, Aerobic exercise - Axial Spondyloarthritis (AxSpA), Aerobic Exercise | Not applicable | Completed | Yeşim Ozge Gunduz Gul | 54 | 2021-11-01 | 2024-11-21 |
| A Real-world Study of Imraldi® Use Adalimumab - Arthritis, Rheumatoid (RA), Axial Spondyloarthritis (axSpA) | Completed | Biogen | 1000 | 2019-06-30 | 2023-04-18 | |
| Multimodal Pulmonary Rehabilitation in Radiographic Axial Spondyloarthritis Multimodal Pulmonary Rehabilitation - Axial Spondyloarthritis (AxSpA) | Not applicable | Completed | Balikesir University | 20 | 2018-05-30 | 2026-02-25 |
| Evaluation of the Expression and Functions of the KIR3DL2 Receptor and the Anti-inflammatory Activity of IPH4102 in Blood Samples blood samples - Axial Spondyloarthritis (axSpA), Ankylosing Spondylitis (AS) | Not applicable | Completed | Assistance Publique Hopitaux De Marseille | 24 | 2017-12-18 | 2026-05-08 |
| A Study to Assess the Effects of Certolizumab Pegol on the Reduction of Anterior Uveitis (AU) Flares in Axial Spondyloarthritis Subjects With a Documented History of AU Certolizumab Pegol - Axial Spondyloarthritis (axSpA), Anterior Uveitis (AU) | Phase 4 | Completed | UCB Biopharma SRL | 89 | 2016-12-21 | 2026-06-23 |
| A Multicenter, Postmarketing Study Evaluating the Concentration of Cimzia® in Mature Breast Milk of Lactating Mothers Breast milk sampling, Certolizumab Pegol - Axial Spondyloarthritis (AxSpA), Non-radiographic Evidence-AxSpA | Phase 1 | Completed | UCB BIOSCIENCES, Inc. | 17 | 2014-09-01 | 2018-04-03 |
| A Multicener, Postmarketing Study Evaluating the Transfer of Cimzia From the Mother to the Infant Via the Placenta Blood sampling from mother, Blood sampling from infant, Blood sampling from umbilical cord - Axial Spondyloarthritis (AxSpA), Non-radiographic Evidence-AxSpA | Phase 1 | Completed | UCB BIOSCIENCES, Inc. | 37 | 2014-01-01 | 2019-06-21 |
Axial Spondyloarthritis (16) · Spondylitis, Ankylosing (6) · Arthritis, Psoriatic (4) · Arthritis, Rheumatoid (4) · Crohn Disease (3) · Autoimmune Diseases (2) · Non-Radiographic Axial Spondyloarthritis (2) · Breast Feeding (1) · Colitis, Ulcerative (1) · Disease (1) · Dyspnea (1) · Rheumatic Diseases (1) · Spondylarthritis (1) · Uveitis, Anterior (1)
Ankylosis (16) · Arthritis (16) · Bone Diseases (16) · Joint Diseases (16) · Musculoskeletal Diseases (16) · Spinal Diseases (16) · Spondylarthropathies (16) · Spondylitis (16) · Spondylarthritis (15) · Connective Tissue Diseases (5) · Skin and Connective Tissue Diseases (5) · Immune System Diseases (4) · Psoriasis (4) · Rheumatic Diseases (4) · Skin Diseases (4)
Certolizumab Pegol (3) · Adalimumab (1) · Blood Specimen Collection (1) · Exercise (1) · Physical Therapy Modalities (1) · Sagittal Abdominal Diameter (1) · mycophenolic adenine dinucleotide (1) · secukinumab (1) · upadacitinib (1)
UCB BIOSCIENCES, Inc. (2) · Assistance Publique - Hôpitaux de Paris (1) · Assistance Publique Hopitaux De Marseille (1) · Balikesir University (1) · Biogen (1) · Chinese PLA General Hospital (1) · Grey Wolf Therapeutics (1) · Istanbul University - Cerrahpasa (1) · Royal United Hospitals Bath NHS Foundation Trust (1) · Sint Maartenskliniek (1) · The University of Texas Health Science Center, Houston (1) · UCB Biopharma SRL (1) · University of Bonn (1) · Yeşim Ozge Gunduz Gul (1) · Ángel Alberich Bayarri (1)
Netherlands (5) · Germany (4) · Spain (4) · France (3) · Turkey (Türkiye) (3) · United States (3) · Belgium (2) · Poland (2) · Switzerland (2) · United Kingdom (2) · Australia (1) · China (1) · Czechia (1) · Ireland (1) · Italy (1)
Ajda Bal, MD, Professor (1) · Jian Zhu (1) · Raj Sengupta, Professor (1) · Savannah M Bowman, MD (1)
PMID 28814432, PMID 29030361, PMID 33854572, PMID 36124947, PMID 37632666, PMID 41919656
2016 (1), 2025 (1)