2 terminated, 1 completed, 1 enrolling by invitation, 1 recruiting. 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 1 | Terminated 1 |
Follow ALSP: new trials by email Literature Review of ALSP trials Research Report on ALSP
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of VGL101 in Patients With Adult-Onset Leukoencephalopathy With Axonal Spheroids and Pigmented Glia VGL101 - ALSP | Phase 2 | Terminated | Vigil Neuroscience, Inc. | 20 | 2022-12-14 | 2025-06-11 |
| Natural History Study in Adult-Onset Leukoencephalopathy With Axonal Spheroids and Pigmented Glia No intervention - ALSP | Terminated | Vigil Neuroscience, Inc. | 56 | 2021-09-13 | 2025-08-13 | |
| A Study to Assess CSF1R-related Leukoencephalopathy After Stem Cell Transplantation CSF1R-related Leukoencephalopathy, ALSP | Enrolling by invitation | Mayo Clinic | 20 | 2020-07-21 | 2026-01-08 | |
| LeukoSEQ: Whole Genome Sequencing as a First-Line Diagnostic Tool for Leukodystrophies Leukodystrophy, White Matter Disease | Completed | Children's Hospital of Philadelphia | 236 | 2017-01-06 | 2025-11-10 | |
| The Myelin Disorders Biorepository Project Leukodystrophy, White Matter Disease | Recruiting | Children's Hospital of Philadelphia | 12000 | 2016-12-08 | 2025-10-23 |
Leukoencephalopathies (5) · Hereditary Diffuse Leukoencephalopathy with Spheroids (3) · Adrenoleukodystrophy (2) · Aicardi-Goutieres syndrome (2) · Alexander Disease (2) · Alexanders leukodystrophy (2) · Allan-Herndon-Dudley syndrome (2) · Attention Deficit Disorder with Hyperactivity (2) · CADASIL (2) · Canavan Disease (2) · Charcot-Marie-Tooth Disease (2) · Cockayne Syndrome (2) · Gangliosidoses (2) · Gangliosidoses, GM2 (2) · Leukodystrophy, Globoid Cell (2)
Brain Diseases (5) · Central Nervous System Diseases (5) · Nervous System Diseases (5) · Abnormalities, Multiple (2) · Adrenal Gland Diseases (2) · Adrenal Insufficiency (2) · Arthritis (2) · Arthritis, Rheumatoid (2) · Attention Deficit and Disruptive Behavior Disorders (2) · Autoimmune Diseases (2) · Bone Diseases (2) · Bone Diseases, Developmental (2) · Brain Diseases, Metabolic (2) · Brain Diseases, Metabolic, Inborn (2) · Brain Infarction (2)
Children's Hospital of Philadelphia (2) · Vigil Neuroscience, Inc. (2) · Mayo Clinic (1)
United States (5) · Germany (2) · Netherlands (2) · United Kingdom (2) · Brazil (1) · Canada (1) · France (1)
Adeline Vanderver, MD (2) · Zbigniew K Wszolek, MD (1)
U01NS106845 (1), U54NS115052 (1)