4 active not recruiting, 4 recruiting, 4 terminated, 2 completed. 10 Phase 2, 8 Phase 1, 2 Phase 3, 1 Not applicable.
Follow Advanced Soft-tissue Sarcoma: new trials by email Literature Review of Advanced Soft-tissue Sarcoma trials Research Report on Advanced Soft-tissue Sarcoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Trial of Cadonilimab With Adriamycin in Patients With Advanced Soft Tissue Sarcoma Cadonilimab, Adriamycin - Advanced Soft-tissue Sarcoma | Phase 2 | Recruiting | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 53 | 2024-10-09 | 2025-07-18 |
| LINNOVATE: Lurbinectedin, Ipilimumab and Nivolumab for Soft Tissue Sarcoma Lurbinectedin - Advanced Soft-tissue Sarcoma | Phase 1 / Phase 2 | Unknown | ERLINDA M GORDON | 40 | 2023-06-07 | 2024-07-05 |
| Phase I/II of LB-100 Plus Doxorubicin vs. Doxorubicin Alone in First Line of Advanced Soft Tissue Sarcomas LB-100 plus Doxorrubicin, Doxorubicin - Advanced Soft-tissue Sarcoma | Phase 1 / Phase 2 | Active not recruiting | Grupo Espanol de Investigacion en Sarcomas | 152 | 2023-05-29 | 2025-03-21 |
| Study of NY-ESO-1 TCR-T in Advanced Soft Tissue Sarcoma NY-ESO-1 TCR-T - Advanced Soft-tissue Sarcoma | Not applicable | Recruiting | Shenzhen University General Hospital | 20 | 2022-11-11 | 2022-11-22 |
| Combination of Pembrolizumab and Cabozantinib in Patients With Advanced Sarcomas Association of pembrolizumab + cabozantinib - Soft Tissue Sarcoma Adult, Advanced Soft-tissue Sarcoma | Phase 2 | Recruiting | Institut Bergonié | 119 | 2022-04-25 | 2025-10-07 |
| HDM201 and Pazopanib in Patients With P53 Wild-type Advanced/Metastatic Soft Tissue Sarcomas Pazopanib, HDM201 - Advanced Soft-tissue Sarcoma, Metastatic Soft-tissue Sarcoma | Phase 1 / Phase 2 | Active not recruiting | Centre Leon Berard | 47 | 2022-04-15 | 2026-06-22 |
| A 3 Arm Randomized Study on Health-related QoL of Elderly Patients With Advanced Soft Tissue Sarcoma Doxorubicin, Cyclophosphamide Oral Product, Prednisolone - Advanced Soft-tissue Sarcoma | Phase 3 | Terminated | European Organisation for Research and Treatment of Cancer - EORTC | 14 | 2022-04-11 | 2024-02-22 |
| Bintrafusp Alfa and Doxorubicin Hydrochloride in Treating Patients With Advanced Sarcoma Bintrafusp alfa, Doxorubicin - Advanced Soft-tissue Sarcoma, Metastatic Soft-tissue Sarcoma | Phase 2 | Active not recruiting | Institut Bergonié | 80 | 2022-03-01 | 2026-07-24 |
| Lurbinectedin + Doxorubicin In Leiomyosarcoma Lurbinectedin, Doxorubicin - Advanced Soft-tissue Sarcoma, Metastatic Soft-tissue Sarcoma | Phase 1 / Phase 2 | Active not recruiting | Massachusetts General Hospital | 62 | 2022-02-04 | 2026-08-27 |
| Study on Tolerability and Pharmacokinetics of TQB2858 Injection in Subjects With Advanced Malignant Tumors TQB2858 injection - Advanced Cancer, Advanced Soft-tissue Sarcoma | Phase 1 / Phase 2 | Terminated | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 8 | 2022-01-14 | 2024-01-18 |
| Multicohort Trial of Different Schemes of PM14 in Monotherapy and in Combination with Radiotherapy in Soft Tissue Sarcomas and Other Solid Tumor PM14 - Advanced Soft-tissue Sarcoma, Advanced L-sarcomas | Phase 1 / Phase 2 | Recruiting | Grupo Espanol de Investigacion en Sarcomas | 195 | 2021-11-23 | 2025-03-21 |
| Camsirubicin + Pegfilgrastim to Determine MTD in ASTS Camsirubicin - Advanced Soft-tissue Sarcoma | Phase 1 | Terminated | Monopar Therapeutics | 14 | 2021-09-22 | 2024-05-16 |
| Combining Epigenetic And Immune Therapy to Beat Cancer. Durvalumab, Tazemetostat - Advanced Solid Tumor, Advanced Colorectal Carcinoma | Phase 2 | Completed | Institut Bergonié | 164 | 2021-07-23 | 2026-03-06 |
| Comparison of Oral Cyclophosphamide vs Doxorubicin in ≥65 Years Old Advanced or Metastatic Soft Tissue Sarcoma Patients Doxorubicin, Cyclophosphamide - Advanced Soft-tissue Sarcoma, Metastatic Soft-tissue Sarcoma | Phase 3 | Unknown | UNICANCER | 214 | 2021-06-18 | 2025-03-25 |
| Tazemetostat in Combination With Doxorubicin as Frontline Therapy for Advanced Epithelioid Sarcoma Tazemetostat, Doxorubicin HCl - Advanced Soft-tissue Sarcoma, Advanced Epithelioid Sarcoma | Phase 1 | Terminated | Epizyme, Inc. | 25 | 2019-12-19 | 2026-01-07 |
| Geriatric Assessmen of Elderly "Unsuited" Patients Receiving Trabectedin in First Line Treatment For Advanced Soft Tissue Sarcomas (STS) No Intervention - Advanced Soft-tissue Sarcoma, Metastatic Soft-tissue Sarcoma | Completed | GWT-TUD GmbH | 72 | 2017-02-02 | 2022-04-04 |
Sarcoma (8) · Tertiary Lymphoid Structures (2) · Colorectal Neoplasms (1) · Histiocytoma, Malignant Fibrous (1) · Neoplasm Metastasis (1) · Osteosarcoma (1) · Pancreatic Neoplasms (1) · Sarcoma, Ewing (1)
Neoplasms (8) · Neoplasms by Histologic Type (8) · Neoplasms, Connective and Soft Tissue (8) · Pathological Conditions, Anatomical (2) · Pathological Conditions, Signs and Symptoms (2) · Colonic Diseases (1) · Digestive System Diseases (1) · Digestive System Neoplasms (1) · Endocrine Gland Neoplasms (1) · Endocrine System Diseases (1) · Gastrointestinal Diseases (1) · Gastrointestinal Neoplasms (1) · Histiocytoma (1) · Intestinal Diseases (1) · Intestinal Neoplasms (1)
Doxorubicin (7) · PM 01183 (2) · tazemetostat (2) · Cyclophosphamide (1) · Ipilimumab (1) · LB100 (1) · Nivolumab (1) · Prednisolone (1) · Prednisone (1) · bintrafusp alfa protein, human (1) · cabozantinib (1) · durvalumab (1) · pazopanib (1) · siremadlin (1)
Institut Bergonié (3) · Grupo Espanol de Investigacion en Sarcomas (2) · Centre Leon Berard (1) · Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (1) · ERLINDA M GORDON (1) · Epizyme, Inc. (1) · European Organisation for Research and Treatment of Cancer - EORTC (1) · GWT-TUD GmbH (1) · Massachusetts General Hospital (1) · Monopar Therapeutics (1) · Shenzhen University General Hospital (1) · UNICANCER (1) · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (1)
France (5) · United States (4) · China (3) · Spain (2) · Austria (1) · Canada (1) · Cyprus (1) · Germany (1) · Jordan (1) · Switzerland (1) · Taiwan (1) · United Kingdom (1)
Ana Sebio (1) · Bernd Kasper, Prof. (1) · Claudia Valverde (1) · Erlinda M Gordon, MD (1) · Gregory Cote, M.D. Ph.D (1) · Holli Carlson (1) · Li Yu, Dr (1) · Olivier Mir, M.D (1) · Thibaud Valentin, M.D (1) · Winette van der Graaf (1)
2019 (2), 2018 (1)