7 completed, 3 recruiting, 1 enrolling by invitation, 1 not yet recruiting. 6 Not applicable, 4 Phase 4, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 3, Enrolling by invitation 1, Not yet recruiting 1, Recruiting 1 |
| Phase 4 | 4 | Recruiting 2, Completed 1, Terminated 1 |
| Phase 2 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow ACUTE SINUSITIS: new trials by email Literature Review of ACUTE SINUSITIS trials Research Report on ACUTE SINUSITIS
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparative Effectiveness of Available Treatments for Sinus and Ear Infections in Children (Acute Sinusitis) Amoxicillin, Amoxi Clavulanate, Amoxicillin Placebo - ACUTE SINUSITIS, Sinusitis | Phase 4 | Recruiting | Nader Shaikh | 1100 | 2026-10-01 | 2026-10-20 |
| Efficacy of Bee Venom Phonophoresis in Treating Chronic Sinusitis: Bee Venom Phonophoresis, Standard Care (oral decongestants + saline nasal irrigation) - Chronic Sinusitis, Acute Sinusitis | Not applicable | Not yet recruiting | Sinai University | 30 | 2026-08-15 | 2026-08-04 |
| Efficacy and Safety of Jinhua Qinggan Granules (JHQG) for the Use of Acute Upper Respiratory Infection Jinhua Qinggan Granules, Placebo - Acute Rhinitis, Acute Pharyngitis | Phase 3 | Completed | University of Karachi | 546 | 2026-01-24 | 2026-07-28 |
| Improving Patient-centered Communication and Antibiotic Use With Information Sheets for Acute Respiratory Tract Infections: A Study Protocol ARTI Info-sheets - Acute Bronchitis, ACUTE SINUSITIS | Not applicable | Enrolling by invitation | Research Unit for General Practice in Aalborg | 1144 | 2026-01-05 | 2026-02-03 |
| Impact of a Multimodal Intervention on Antibiotic Prescribing for Respiratory Infections in Primary Care Antibiotic prescribing according to guidelines - Angina, Acute Bronchiolitis | Not applicable | Recruiting | University Hospital, Caen | 4500 | 2025-12-01 | 2026-01-22 |
| Effects of Saccharomyces Boulardii CNCM I-745 on Antibiotic-Associated Perturbation in Children Treated for Acute Respiratory Infections (RESTORE Study) Amoxicillin-Clavulanic acid 600mg - 42.9 mg/ 5 mL oral suspension, Saccharomyces boulardii CNCM I-745 - Antibiotic Associated Diarrhea, Acute Otitis Media | Phase 4 | Completed | Eskisehir Osmangazi University | 100 | 2025-08-01 | 2026-09-11 |
| Nasal Steroids, Irrigation, Oral Antibiotics, and Subgroup Targeting for Effective Management of Acute Sinusitis amoxicillin/clavulanate potassium, Placebo, Budesonide nasal spray - Sinus Infection, Acute Sinusitis | Phase 4 | Recruiting | Daniel Merenstein | 3720 | 2023-11-21 | 2026-03-03 |
| Broad Implementation of Outpatient Stewardship Broad Implementation of Outpatient Stewardship (BIOS) intervention - Acute Respiratory Tract Infection, Otitis Media | Not applicable | Completed | Children's Hospital of Philadelphia | 1032 | 2022-10-31 | 2026-02-09 |
| Safety and Efficacy of Cefecin Tab. in Patients With Acute Sinusitis Cefecin Tab., Omnicef Cap. - Acute Sinusitis | Phase 4 | Terminated | Korea United Pharm. Inc. | 284 | 2015-08-31 | 2020-12-11 |
| Comparative Effectiveness of Antibiotics for Respiratory Infections Broad-spectrum antibiotics, Narrow-spectrum antibiotics - Acute Otitis Media, Acute Sinusitis | Completed | Children's Hospital of Philadelphia | 2472 | 2014-01-01 | 2019-07-08 | |
| Gulf War Illness Nasal Irrigation Study Nasal Irrigation - Saline, Nasal Irrigation - Xylitol - Persian Gulf Syndrome, Chronic Sinusitis | Phase 2 | Completed | University of Wisconsin, Madison | 40 | 2012-10-01 | 2019-05-21 |
| Antimicrobial Stewardship for Primary Care Pediatricians Antimicrobial Stewardship Bundle - Acute Sinusitis, Streptococcal Pharyngitis | Not applicable | Completed | Children's Hospital of Philadelphia | 170 | 2010-06-01 | 2013-03-07 |
| Pilot Study to Determine Efficacy of Cyclamen Europaeum Extract Nasal Spray in Patients With Acute Sinusitis Cyclamen Europaeum - ACUTE SINUSITIS | Not applicable | Completed | Dey | 48 | 2007-11-01 | 2013-06-04 |
Otitis Media (4) · Sinusitis (4) · Bronchitis (2) · Pharyngitis (2) · Respiratory Tract Infections (2) · Angina Pectoris (1) · Bronchiolitis Obliterans Syndrome (1) · Common Cold (1) · Community-Acquired Pneumonia (1) · Fatigue (1) · Influenza, Human (1) · Laryngitis (1) · Nasopharyngitis (1) · Persian Gulf Syndrome (1) · Pneumonia (1)
Infections (9) · Otorhinolaryngologic Diseases (9) · Respiratory Tract Diseases (9) · Respiratory Tract Infections (7) · Nose Diseases (5) · Ear Diseases (4) · Lung Diseases (4) · Otitis (4) · Paranasal Sinus Diseases (4) · Bronchial Diseases (3) · Lung Diseases, Obstructive (3) · Pharyngeal Diseases (3) · Stomatognathic Diseases (3) · Pathological Conditions, Signs and Symptoms (2) · RNA Virus Infections (2)
Amoxicillin-Potassium Clavulanate Combination (3) · Amoxicillin (1) · Budesonide (1) · Cefdinir (1) · Methods (1) · Nasal Decongestants (1) · Standard of Care (1) · Suspensions (1) · cefetamet pivoxyl (1) · jinhua qinggan granules (1)
Children's Hospital of Philadelphia (3) · Daniel Merenstein (1) · Dey (1) · Eskisehir Osmangazi University (1) · Korea United Pharm. Inc. (1) · Nader Shaikh (1) · Research Unit for General Practice in Aalborg (1) · Sinai University (1) · University Hospital, Caen (1) · University of Karachi (1) · University of Wisconsin, Madison (1)
United States (7) · Denmark (1) · Egypt (1) · France (1) · Pakistan (1) · Turkey (Türkiye) (1)
Jeffrey S Gerber, MD, PhD (2) · Angelique Barreto, MD (1) · Dan Merenstein, MD (1) · David P Rabago, MD (1) · Jeffrey Gerber, MD PhD MSCE (1) · Nader Shaikh, MD (1) · Rachel Molander, MD (1)