8 unknown, 5 completed, 4 recruiting, 1 active not recruiting. 18 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 18 | Unknown 8, Completed 5, Recruiting 4, Active not recruiting 1 |
Follow Acute Myeloid Leukemia: new trials by email Literature Review of Acute Myeloid Leukemia trials Research Report on Acute Myeloid Leukemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study to Assess Adverse Events and Change in Disease Activity of Oral Venetoclax in Combination With Subcutaneous (SC) or Intravenous (IV) Azacitidine in Newly Diagnosed Adult Participants With Acute Myeloid Leukemia (AML) Who Are Ineligible for Standard Induction Therapy in India Venetoclax, Azacitidine - Acute Myeloid Leukemia | Phase 4 | Recruiting | AbbVie | 100 | 2025-07-24 | 2026-09-11 |
| Oral Azacitidine in Transplant-Eligible Patients With Acute Myeloid Leukemia (AML) Suffering From Health-Inequality Oral Azacitidine - Acute Myeloid Leukemia | Phase 4 | Recruiting | Virginia Commonwealth University | 12 | 2024-11-07 | 2026-05-29 |
| RIC Allo-HSCT vs. Venetoclax-Based Consolidation in Elderly AML Patients After First CR Venetoclax, Allogeneic transplant - Acute Myeloid Leukemia | Phase 4 | Recruiting | He Huang | 118 | 2024-07-17 | 2024-08-26 |
| Venetoclax With Hypomethylating Agents in Newly Diagnosed AML Unfit for Intensive Chemotherapy Venetoclax, Azacitidine, Decitabine - Acute Myeloid Leukemia | Phase 4 | Completed | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | 24 | 2022-06-01 | 2026-08-21 |
| Study of the Effectiveness and Safety of Daunorubicin /Idarubicin ± Silibinin in Treating Newly Diagnosed AML (Non-M3). daunomycin/Idarubicin+ Silybinin, daunomycin/Idarubicin - Acute Myeloid Leukemia, Newly Diagnosed | Phase 4 | Recruiting | Fujian Medical University Union Hospital | 100 | 2022-04-01 | 2026-05-01 |
| Fludarabine and Cytarabine Versus High-dose Cytarabine for CBF-AML Fludarabine, Cytarabine - Acute Myeloid Leukemia, Core-Binding Factor | Phase 4 | Completed | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 68 | 2017-01-01 | 2024-10-01 |
| Decitabine Versus Conventional Chemotherapy for Maintenance Therapy of Acute Myeloid Leukemia With t(8;21) Decitabine, Daunorubicin, Cytarabine, Mitoxantrone, Cytarabine - Acute Myeloid Leukemia | Phase 4 | Unknown | The First Hospital of Jilin University | 180 | 2017-01-01 | 2017-01-20 |
| G-CSF Alone or Combination With GM-CSF on Prevention and Treatment of Infection in Children With Malignant Tumor GM-CSF, G-CSF, GM-CSF and G-CSF - Acute Myeloid Leukemia, Acute Lymphoid Leukemia | Phase 4 | Unknown | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | 405 | 2016-09-27 | 2018-10-17 |
| CINC424A2X01B Rollover Protocol ruxolitinib, panobinostat - Primary Myelofibrosis, Polycythemia Vera | Phase 4 | Active not recruiting | Novartis Pharmaceuticals | 279 | 2015-03-05 | 2026-10-19 |
| Interferon for the Intervention of Molecular Relapse in t (8; 21) AML After Allo-HSCT Interferon-alpha - Acute Myeloid Leukemia | Phase 4 | Unknown | Peking University People's Hospital | 40 | 2013-10-01 | 2016-09-29 |
| Respiratory Viral Infections During Acute Myeloid Leukemia (AML)Chemotherapy Related Aplasia Multiplex respiratory viral PCR - Acute Myeloid Leukemia | Phase 4 | Completed | Centre Hospitalier Universitaire, Amiens | 119 | 2013-04-01 | 2018-04-23 |
| AML1-ETO Acute Myeloid Leukemia With Fludarabine and Cytarabine Chemotherapy Fludarabine, Cytarabine - Acute Myeloid Leukemia, AML1-ETO Fusion Protein Expression | Phase 4 | Unknown | Changhai Hospital | 62 | 2010-11-01 | 2013-12-31 |
| Idarubicin at Different Dosages as Induction Therapy for Newly Diagnosed Acute Myeloid Leukaemia Idarubicin(8mg/m2) and cytosine arabinoside, Idarubicin(10mg/m2), cytosine arabinoside - Acute Myeloid Leukemia | Phase 4 | Unknown | Guangdong Provincial People's Hospital | 400 | 2010-03-01 | 2014-10-29 |
| 3 Anthracyclines, 2 Types of Consolidation With Different ARA-C Doses and Maintenance in Adult Acute Myeloid Leukemia high dose ARA-C, standard dose ARA-C - Acute Myeloid Leukemia | Phase 4 | Unknown | National Research Center for Hematology, Russia | 245 | 2010-01-01 | 2014-04-07 |
| Early Tapering of Immunosuppressive Agents to Immunomodulation to Improve Survival of AML Patients Cyclosporine, routine reduction of immunosuppressive drugs(cyclosporine) - Acute Myeloid Leukemia, Disorder Related to Bone Marrow Transplantation | Phase 4 | Unknown | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 100 | 2010-01-01 | 2017-05-12 |
| Maintenance Therapy With Ceplene® (Histamine) and IL-2 on Immune Response and MRD in Acute Myeloid Leukemia histamine dihydrochloride and IL-2 - Acute Myeloid Leukemia | Phase 4 | Completed | Cytovia, Inc. | 84 | 2009-07-01 | 2017-11-29 |
| Fludarabine, Cytarabine, Topotecan in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia Topotecan, Fludarabine, Cytarabine - Acute Myeloid Leukemia | Phase 4 | Completed | PETHEMA Foundation | 47 | 2003-05-01 | 2008-11-18 |
| Efficacy of G-CSF-Priming in Elderly AML Patients Cytarabine, Etoposide, Idarubicin - Acute Myeloid Leukemia | Phase 4 | Unknown | Johann Wolfgang Goethe University Hospital | 250 | 2000-01-01 | 2005-10-26 |
Leukemia, Myeloid, Acute (18) · Bronchiolitis Obliterans Syndrome (1) · Graft vs Host Disease (1) · Hepatoblastoma (1) · Leukemia (1) · Lymphoma (1) · Neoplasm, Residual (1) · Neuroblastoma (1) · Polycythemia Vera (1) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (1) · Primary Myelofibrosis (1) · Recurrence (1) · Retinoblastoma (1) · Thalassemia (1)
Hematologic Diseases (18) · Hemic and Lymphatic Diseases (18) · Leukemia, Myeloid (18) · Neoplasms (18) · Neoplasms by Histologic Type (18) · Leukemia (17) · Immune System Diseases (2) · Neoplasms by Site (2) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Anemia (1) · Anemia, Hemolytic (1) · Anemia, Hemolytic, Congenital (1) · Bone Marrow Diseases (1) · Bone Marrow Neoplasms (1)
Cytarabine (7) · Idarubicin (4) · fludarabine (4) · Azacitidine (3) · venetoclax (3) · Daunorubicin (2) · Decitabine (2) · Granulocyte Colony-Stimulating Factor (2) · fludarabine phosphate (2) · Cyclosporine (1) · Etoposide (1) · Granulocyte-Macrophage Colony-Stimulating Factor (1) · Histamine (1) · Immunosuppressive Agents (1) · Interferon-alpha (1)
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine (2) · AbbVie (1) · Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh (1) · Centre Hospitalier Universitaire, Amiens (1) · Changhai Hospital (1) · Cytovia, Inc. (1) · Fujian Medical University Union Hospital (1) · Guangdong Provincial People's Hospital (1) · He Huang (1) · Johann Wolfgang Goethe University Hospital (1) · National Research Center for Hematology, Russia (1) · Novartis Pharmaceuticals (1) · PETHEMA Foundation (1) · Peking University People's Hospital (1) · The First Hospital of Jilin University (1)
China (9) · France (2) · Germany (2) · India (2) · Russia (2) · Spain (2) · Sweden (2) · Australia (1) · Bangladesh (1) · Belgium (1) · Bulgaria (1) · Canada (1) · Chile (1) · Greece (1) · Hungary (1)
Xianmin Song, Doctor (2) · Bueno Javier, Dr (1) · Fang Yongjun, Ph.D (1) · Gao Fei, Ph.D (1) · Hu Shaoyan, Ph.D (1) · Keri Maher, DO (1) · Li Aimin, Ph.D (1) · Liang Changda, Master (1) · Liu Wei, Ph.D (1) · Mats L Brune, MD, PhD (1)
PMID 10231138, PMID 10583235, PMID 12627513, PMID 16110027, PMID 16197446, PMID 18398750, PMID 19822296, PMID 20542125, PMID 20625136, PMID 22318524, PMID 22512017, PMID 22871557, PMID 23376821, PMID 25314773, PMID 26863635, PMID 28235771, PMID 28529313, PMID 28721449, PMID 29250743, PMID 30076280, PMID 30315349, PMID 32687450, PMID 32786187, PMID 34367728, PMID 34614506, PMID 34956230, PMID 35154096, PMID 35704787, PMID 36863709, PMID 3896457
2014 (1)