4 completed, 3 recruiting, 1 active not recruiting, 1 not yet recruiting. 6 Not applicable, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Recruiting 3, Completed 2, Active not recruiting 1 |
| Phase 2 | 1 | Not yet recruiting 1 |
Follow Acute Hypoxic Respiratory Failure: new trials by email Literature Review of Acute Hypoxic Respiratory Failure trials Research Report on Acute Hypoxic Respiratory Failure
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Precision Medicine Adaptive Network Platform Trial in Hypoxemic Acute Respiratory Failure Simvastatin, Baricitinib - ARDS (Acute Respiratory Distress Syndrome), Acute Hypoxic Respiratory Failure | Phase 2 | Not yet recruiting | University of Colorado, Denver | 300 | 2026-09-01 | 2026-10-08 |
| WIN Ratio Analysis to Determine a Strategy of Non- Invasive SUpport for Respiratory Failure in the EmeRgency Department Non-Invasive Positive Pressure Ventilation, High Flow Nasal Oxygen - Acute Hypoxic Respiratory Failure, Acute Respiratory Distress Syndrome (ARDS) | Not applicable | Recruiting | Ohio State University | 500 | 2026-08-18 | 2026-10-01 |
| Inspiratory Effort-Targeted Pressure Support Ventilation (IT-PSV) Trial PMI-targeted pressure support setting and adjustment, VT/RR-targeted pressure support setting and adjustment - Critical Care, Acute Hypoxic Respiratory Failure | Not applicable | Recruiting | Capital Medical University | 619 | 2026-01-19 | 2026-01-21 |
| A Pilot Trial of Pressure Muscle Index-Targeted PSV Trial PMI-targeted PSV setting, VT/RR-targeted PSV setting - Critical Care, Acute Hypoxic Respiratory Failure | Not applicable | Recruiting | Capital Medical University | 60 | 2025-01-20 | 2025-02-07 |
| Optimizing Care in Critically Ill at UCHealth by Liberalizing the Target O2 in Mechanically-ventilated ICU Patients Education, Epic notification alert - Respiratory Failure, Acute Hypoxemic Respiratory Failure | Not applicable | Active not recruiting | University of Colorado, Denver | 3600 | 2024-09-01 | 2026-09-28 |
| Noninvasive Ventilation Breathing Test Guiding Weaning in Patients With Acute Hypoxic Respiratory Failure Noninvasive ventilation breathing test guiding sequential invasive Ventilation and noninvasive ventilation weaing protocol, The standard SBT guiding weaning group - Acute Hypoxic Respiratory Failure | Not applicable | Completed | West China Hospital | 160 | 2024-08-25 | 2026-06-29 |
| Personalized Noninvasive Support in Acute Hypoxemic Respiratory Failure Noninvasive support - Acute Hypoxic Respiratory Failure | Not applicable | Completed | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 20 | 2024-01-12 | 2025-09-30 |
| Analysis of Advanced Physiological Ventilatory Parameters During Spontaneous Breathing Effort in Patients with Acute Hypoxemic Respiratory Failure Acute Hypoxic Respiratory Failure | Completed | Hospital del Mar Research Institute (IMIM) | 31 | 2020-12-01 | 2024-11-20 | |
| Respiratory Drive and Inspiratory Effort in COVID-19 Associated ARDS Respiratory drive and effort assessment - ARDS, Human, COVID-19 Respiratory Infection | Completed | University of Turin, Italy | 56 | 2020-11-21 | 2024-01-25 |
Respiratory Distress Syndrome (2) · Respiratory Insufficiency (2) · Acute Lung Injury (1) · COVID-19 (1) · Hypoxia (1) · Pulmonary Disease, Chronic Obstructive (1) · Ventilator-Induced Lung Injury (1)
Respiratory Tract Diseases (5) · Lung Diseases (4) · Respiration Disorders (3) · Lung Injury (2) · Pathological Conditions, Signs and Symptoms (2) · Chronic Disease (1) · Coronaviridae Infections (1) · Coronavirus Infections (1) · Disease Attributes (1) · Infections (1) · Lung Diseases, Obstructive (1) · Nidovirales Infections (1) · Pathologic Processes (1) · Pneumonia (1) · Pneumonia, Viral (1)
Educational Status (1) · Simvastatin (1) · baricitinib (1)
Capital Medical University (2) · University of Colorado, Denver (2) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · Hospital del Mar Research Institute (IMIM) (1) · Ohio State University (1) · University of Turin, Italy (1) · West China Hospital (1)
China (3) · Italy (2) · United States (2) · Spain (1)
Jian-Xin Zhou, MD (2) · Neil Aggarwal, MD (2) · Domenico Luca Grieco (1) · Henry E Wang, MD, MS (1) · Jarrod Mosier, MD (1) · Lai Wei, PhD (1) · Mark Tidswell, MD (1) · Robert Silbergleit, MD (1) · Valerie Durkalski-Mauldin, PhD (1) · Vito Fanelli, MD, PhD (1) · William Meurer, MD (1) · Xiaoyi Liu (1) · Yan Kang (1) · Yongfang Zhou (1)
PMID 39582975, PMID 40758388, PMID 42191205
U24HL175258 (1), UG3HL175260 (1)