153 completed, 20 terminated, 12 recruiting, 7 active not recruiting. 202 Phase 1, 15 Phase 2.
By phase and status
Phase Trials Status Phase 1 202 Completed 153 , Terminated 20 , Recruiting 12 , Active not recruiting 7 , Unknown 6 , Withdrawn 3 , Not yet recruiting 1 Phase 2 15 Completed 8 , Recruiting 2 , Unknown 2 , Active not recruiting 1 , Terminated 1 , Withdrawn 1
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All 202 trials
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix .
Trial Phase Status Sponsor Enrollment Start Updated
Study to Characterise Pharmacokinetics (PK), Pharmacodynamics (PD), and Safety of Anifrolumab Administered Subcutaneously (SC) or Intravenously (IV) Anifrolumab: SC formulation via AI, Anifrolumab: IV formulation, Anifrolumab: SC formulation via aPFS - Systemic Lupus Erythematosus Phase 1 Not yet recruiting 92 2026-10-30 2026-07-07 A Study to Investigate the Safety and Pharmacokinetics of Single- and Multiple-ascending Doses of AZD4916 in Healthy Volunteers AZD4916, Placebo - Healthy Participants Phase 1 Recruiting 160 2026-07-23 2026-09-28 A Study to Evaluate the Safety and Pharmacokinetics of AZD7760 in Healthy Japanese Adults AZD7760, Placebo - Staphylococcus Aureus Bloodstream Infection Phase 1 Active not recruiting 18 2026-06-29 2026-10-06 A Study to Evaluate the Effect of Carbamazepine or Itraconazole on Radiprodil in Healthy Adult Participants Radiprodil, Carbamazepine, Itraconazole (200 mg) - Healthy Adult Participants Phase 1 Active not recruiting 36 2026-06-08 2026-10-21 A Study to Investigate the Effect of Elecoglipron on Rosuvastatin and Atorvastatin in Healthy Participants Elecoglipron, Atorvastatin, Rosuvastatin - Healthy Participants Phase 1 Active not recruiting 48 2026-04-16 2026-08-28 A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD1043 in Healthy Adult Participants Living With Overweight and/or Obesity. AZD1043, Placebo - Healthy Participants, Obesity Phase 1 Recruiting 104 2026-03-30 2026-10-13 A Study to Investigate the Effect of Capivasertib on the Pharmacokinetics of Oral Dextromethorphan (CYP2D6 Substrate) in Healthy Participants Dextromethorphan, Capivasertib - Healthy Participants Phase 1 Completed 42 2026-03-19 2026-07-27 A Phase I Study Comparing the Relative Bioavailability of a Fixed-Dose Combination of Laroprovstat/Rosuvastatin vs Their Single Therapy Products in Healthy Adults Laroprovstat Dose X/Rosuvastatin Dose 1 FCDP test formulation 1, Laroprovstat Dose X/Rosuvastatin Dose 2 FCDP test formulation 1, Laroprovstat Dose X/Rosuvastatin Dose 1 FCDP test formulation 2 - Healthy Participants Phase 1 Completed 44 2026-03-16 2026-06-17 A Study to Investigate the Effect of AZD5004 on Mitiglinide and Pioglitazone in Healthy Participants AZD5004, Mitiglinide, Pioglitazone - Healthy Participants Phase 1 Completed 32 2026-03-13 2026-07-13 A Study to Investigate the Pharmacokinetics of Different Formulations and Safety of AZD5004 in Healthy Participants Aged 18 to 55 Years AZD5004 - Healthy Participants Phase 1 Completed 65 2026-03-05 2026-06-10 A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics With AZD0780 Following Repeated Dose Administration in Healthy Adults With Elevated LDL-C Levels AZD0780, Placebo - Healthy Participants Phase 1 Completed 40 2026-02-24 2026-07-07 A Study to Compare the Pharmacokinetics, Pharmacodynamic, Immunogenicity, and Safety of CKD-706 With US-Dupixent®, and EU-Dupixent® in Healthy Adult Participants. CKD-706, US-Dupixent, EU-Dupixent - Atopic Dermatitis Phase 1 Recruiting 519 2026-02-09 2026-01-23 A Study to Investigate Andexanet Dosing and the Interaction Between Andexanet and Subsequent Enoxaparin in Healthy Participants Andexanet alfa, Rivaroxaban, Apixaban - Healthy Participants Phase 1 Completed 191 2026-01-19 2026-07-09 A Phase I Study to Investigate the Pharmacokinetics and Safety of Capivasertib in Participants With Moderate Hepatic Impairment Capivasertib - Moderate Hepatic Impairment Phase 1 Recruiting 20 2026-01-06 2026-09-09 A Study to Investigate Safety, Tolerability, and Pharmacokinetics of AZD3974 in Healthy Participants AZD3974, Placebo - Healthy Participants Phase 1 Recruiting 176 2025-12-10 2026-10-13 A Study to Investigate the Pharmacokinetics and Safety of Subcutaneous Rilvegostomig in Adult Participants With Advanced Solid Tumors Previously Treated With Standard of Care Therapy IV Rilvegostomig, Recombinant Human Hyaluronidase (rHu), SC Rilvegostomig - Advanced Solid Tumors Phase 1 Recruiting 40 2025-11-25 2026-10-05 A Study to Investigate the Effect of AZD0780 on Metformin Pharmacokinetics in Healthy Adult Volunteers Aged 18 to 55 Years AZD0780, Metformin - Healthy Participants Phase 1 Completed 14 2025-11-10 2026-10-30 A Study of AZD2962, an IRAK4 Inhibitor (IRAK4 [a Body Protein] Blocker), in Participants With Haematologic Neoplasms (Blood Cancers) AZD2962 - Haematologic Neoplasms Phase 1 Recruiting 72 2025-11-03 2026-03-02 Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer AZD0516, AZD9574 - Metastatic Prostate Cancer Phase 1 / Phase 2 Recruiting 283 2025-10-01 2026-10-22 A Master Protocol Study to Investigate Biomarker-guided Novel Anticancer Agent(s) as Monotherapy or Combination Therapy in Participants With Advanced/Recurrent Ovarian Cancer Saruparib - Advanced/Recurrent Ovarian Cancer Phase 1 / Phase 2 Withdrawn 2025-09-02 2026-04-03
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Conditions studied Asthma (14) · Pulmonary Disease, Chronic Obstructive (12) · Diabetes Mellitus, Type 2 (11) · Renal Insufficiency, Chronic (9) · Dyslipidemias (8) · Obesity (8) · Heart Failure (7) · Arthritis, Rheumatoid (4) · Cardiovascular Diseases (4) · Liver Cirrhosis (4) · Renal Insufficiency (4) · Arthritis, Psoriatic (3) · Autoimmune Diseases (3) · Coronary Artery Disease (3) · Crohn Disease (3)
Interventions Itraconazole (9) · Rosuvastatin Calcium (7) · 1-(1-(imidazo(1,2-a)pyridin-6-yl)ethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-(1,2,3)triazolo(4,5-b)pyrazine (6) · Moxifloxacin (6) · capivasertib (6) · AZD4831 (5) · AZD5718 (4) · Allopurinol (4) · Midazolam (4) · Rabeprazole (4) · dapagliflozin (4) · nitisinone (4) · verinurad (4) · AZD9977 (3) · Budesonide (3)
Countries United States (108) · United Kingdom (51) · Germany (37) · Spain (9) · Japan (8) · South Africa (7) · Bulgaria (5) · Australia (4) · Canada (4) · France (4) · South Korea (4) · Poland (3) · Taiwan (3) · China (2) · Italy (2)
Top investigators David Han, MD (5) · Ronald Goldwater, MD (4) · David Han, M.D (2) · Esther Yoon, MD (2) · Muna Albayaty, MBChB, MSc, MFPM (2) · Muna Albayaty, MD (2) · Pablo Forte Soto, MD, MSc, PhD (2) · Rainard Fuhr, Dr. med. (2) · Alen Jambrecina (1)
Results publications PMID 32907575 , PMID 39798707 , PMID 41677208 , PMID 25700806 , PMID 26016741 , PMID 26160357 , PMID 27139036 , PMID 27297209 , PMID 28158463 , PMID 28814432 , PMID 29030361 , PMID 29093180 , PMID 29275332 , PMID 29869298 , PMID 30566758 , PMID 31140114 , PMID 31266654 , PMID 31526218 , PMID 31539289 , PMID 31851518 , PMID 32761612 , PMID 33145642 , PMID 33400845 , PMID 33733338 , PMID 33767059 , PMID 34473343 , PMID 35227647 , PMID 36504291 , PMID 36572571 , PMID 36641607 , PMID 36683419 , PMID 37607661 , PMID 38504437 , PMID 38970537 , PMID 39002122 , PMID 39179458 , PMID 39235870 , PMID 39495467 , PMID 39582128 , PMID 39636565 , PMID 42137960
NIH funding 2016 (4) , 2025 (4) , 2017 (3) , 2014 (2) , 2018 (2) , 2023 (2) , 2019 (1)