139 completed, 9 unknown, 8 terminated, 1 not yet recruiting. 158 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 158 | Completed 139, Unknown 9, Terminated 8, Not yet recruiting 1, Withdrawn 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study to Evaluate Subject Satisfaction With Facial Appearance and Impact of Combined Facial Treatment JUVÉDERM, BOTOX, HArmonyCA Lidocaine - Facial Rhytides, Skin Folds | Phase 4 | Completed | Allergan | 64 | 2023-02-15 | 2025-06-17 |
| HArmonyCa Injectable Gel for Mid Face Soft Tissue Augmentation HArmonyCa Injectable Gel - Soft Tissue Augmentation | Phase 4 | Completed | Allergan | 140 | 2021-10-13 | 2024-09-19 |
| VFORM: Prospective, Open Label, Study to Evaluate VOLIFT With Lidocaine Treatment for FORehead Contouring and Marionette Lines Juvéderm® VOLIFT™ with Lidocaine - Marionette Lines Forehead Contouring | Phase 4 | Completed | Allergan | 163 | 2021-09-15 | 2022-11-30 |
| CoolSculpting® Elite for Non-Invasive Fat Reduction CoolSculpting® Elite System with CoolSculpting® Elite applicators - Non-invasive Fat Reduction | Phase 4 | Completed | Allergan | 110 | 2021-05-18 | 2023-10-05 |
| A Study to Evaluate the Effect of Juvederm Volift With Lidocaine on Aging Hands in Participants Age 35 and Older Juvéderm® VOLIFT with Lidocaine - Skin Depressions, Skin Elasticity | Phase 4 | Completed | Allergan | 75 | 2020-05-20 | 2022-12-12 |
| A Study to Evaluate Androderm®'s Effect on Blood Pressure in Adult Hypogonodal Male Participants Androderm® - Hypogonadism | Phase 4 | Completed | Allergan | 168 | 2020-05-19 | 2022-07-12 |
| Comparative Study of Dexamethasone Implant to Intravitreal Aflibercept in Subjects With Diabetic Macular Edema Dexamethasone implant, Aflibercept - Diabetic Macular Edema | Phase 4 | Completed | The Cleveland Clinic | 23 | 2020-04-10 | 2026-07-29 |
| Evaluation of the Safety and Efficacy of OnabotulinumtoxinA to the Depressor Anguli Oris OnabotulinumtoxinA 50 UNT [Botox Cosmetic] - Aging | Phase 4 | Not yet recruiting | Amir Moradi MD, MBA | 20 | 2020-01-01 | 2020-01-27 |
| A Study to Evaluate the Effectiveness and Safety of OZURDEX® in Patients With Diabetic Macular Edema But Never Treated Dexamethasone Intravitreal Implant - Diabetic Macular Edema | Phase 4 | Completed | Allergan | 82 | 2019-09-05 | 2022-10-07 |
| Increase in Capillary Plexus Density Level Following the Use of Ozurdex for the Treatment of DME Ozurdex Drug Implant Product - Diabetic Macular Edema, Diabetic Retinopathy | Phase 4 | Unknown | Retina Macula Specialists of Miami, LLC | 20 | 2019-08-22 | 2020-03-18 |
| Efficacy and Safety of Deoxycholic Acid Injections for Removal of Adipose Tissue in the "Bra Strap Fat" Region Deoxycholic Acid - Brassiere Strap Fat (BSF), Bra Strap Fat (BSF) | Phase 4 | Completed | Juva Skin & Laser Center | 22 | 2019-07-26 | 2021-04-01 |
| Evaluation of OZURDEX® in Patients With Macular Edema Secondary to Retinal Vein Occlusion in China OZURDEX - Macular Edema, Retinal Vein Occlusion | Phase 4 | Completed | Allergan | 150 | 2019-07-25 | 2023-03-31 |
| Hospital Avoidance Strategies for ABSSSI Dalbavancin - Skin Infection | Phase 4 | Terminated | Washington University School of Medicine | 11 | 2019-03-04 | 2022-12-09 |
| A Study to Evaluate Participant Satisfaction With Facial Appearance Overall and the Aesthetic and Psychosocial Impact of Combined Facial Treatment JUVÉDERM®, BOTOX Cosmetic®, BELKYRA® - Facial Rhytides, Skin Folds, Loss of Volume and Skin Quality | Phase 4 | Completed | Allergan | 59 | 2019-01-22 | 2023-10-31 |
| Botulinum Toxin Pyloroplasty to Reduce Postoperative Nausea and Vomiting After Sleeve Gastrectomy Botulinum toxin pyloroplasty, Normal saline pyloric injection - Bariatric Surgery, Postoperative Nausea and Vomiting | Phase 4 | Completed | Albany Medical College | 84 | 2019-01-07 | 2023-04-10 |
| A Study to Evaluate the Effectiveness of Juvéderm® VOLIFT™ With Lidocaine for Lip Augmentation Juvéderm® VOLIFT™ with Lidocaine - Lip Augmentation | Phase 4 | Completed | Allergan | 60 | 2018-12-19 | 2021-07-28 |
| Steroid vs. Anti-vascular Endothelial Growth Factor for Diabetic Macular Edema Prior to Phacoemulsification Bevacizumab, Ranibizumab, Aflibercept - Diabetic Macular Edema, Cataract | Phase 4 | Completed | Bay Area Retina Associates | 16 | 2018-11-15 | 2025-09-12 |
| XEN-45 Gel Stent Versus Trabeculectomy in Glaucoma: Gold-Standard Pathway Study (GPS) XEN-45 Gel Stent, Trabeculectomy - Glaucoma | Phase 4 | Completed | Allergan | 158 | 2018-10-01 | 2022-07-21 |
| The Movement of Botulinum Toxin Through the Lateral Gastrocnemius Muscle in Humans: An Expanded Examination Botox - Stroke, Muscle Spasticity | Phase 4 | Terminated | Weill Medical College of Cornell University | 4 | 2018-06-15 | 2021-12-29 |
| Kybella With Triamcinolone Injectable sodium deoxycholate, Injectable sodium deoxycholate with Triamcinolone acetate - Adiposity | Phase 4 | Completed | Goldman, Butterwick, Fitzpatrick and Groff | 30 | 2018-03-26 | 2019-05-09 |
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Ocular Hypertension (25) · Glaucoma, Open-Angle (16) · Glaucoma (15) · Dry Eye Syndromes (14) · Acne Vulgaris (8) · Urinary Bladder, Overactive (7) · Macular Edema (6) · Migraine Disorders (5) · Cataract (4) · Hypotrichosis (4) · Muscle Spasticity (4) · Torticollis (4) · Conjunctivitis, Allergic (3) · Retinal Vein Occlusion (3) · Urinary Incontinence (3)
Botulinum Toxins, Type A (42) · Bimatoprost (20) · Calcium Dobesilate (12) · Ophthalmic Solutions (12) · Dexamethasone (11) · Timolol (11) · Latanoprost (10) · Brimonidine Tartrate (7) · Brimonidine Tartrate, Timolol Maleate Drug Combination (7) · Lubricant Eye Drops (7) · Dapsone (5) · Travoprost (5) · Bevacizumab (4) · Carboxymethylcellulose Sodium (4) · Ketorolac (4)
United States (93) · Canada (20) · France (10) · United Kingdom (10) · Germany (8) · South Korea (8) · China (7) · Australia (5) · Brazil (5) · Italy (4) · Spain (4) · Sweden (4) · Belgium (3) · Portugal (3) · Croatia (2)
Esther Jo (2) · Frank A Bucci, Jr., MD (2) · Patrick Gillard (2) · Roger K Cady, MD (2) · Alberto Espay, MD (1) · Amin Boroujerdi (1) · Amir Moradi, MD, MBA (1) · Angus Turner, FRANZCO (1) · Anna Chan (1) · Anna Muslin (1) · Anne McLaughlin (1) · Ava Shamban, MD (1)
PMID 19476406, PMID 25260889, PMID 15985582, PMID 16052120, PMID 17105455, PMID 18402717, PMID 18977811, PMID 19075138, PMID 20384750, PMID 20384751, PMID 20396496, PMID 21174051, PMID 22458918, PMID 23475405, PMID 24006861, PMID 25519810, PMID 25880685, PMID 26059781, PMID 26133547, PMID 29404713, PMID 30293228, PMID 30630956, PMID 31559634, PMID 31713130, PMID 32665528, PMID 32985341, PMID 33451297, PMID 33780567, PMID 33818170, PMID 33955921, PMID 36370233, PMID 36763899, PMID 36849797, PMID 36972738, PMID 40875503, PMID 41393002
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