16 completed, 3 terminated, 1 unknown, 1 withdrawn. 21 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 21 | Completed 16, Terminated 3, Unknown 1, Withdrawn 1 |
| Phase 2 | 1 | Withdrawn 1 |
Follow Zonisamide: new trials by email Literature Review of Zonisamide trials Research Report on Zonisamide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Zonisamide Versus Topiramate in Migraine Zonisamide 50 MG, Topiramate 50 MG - Migraine | Phase 3 | Completed | Kafrelsheikh University | 600 | 2024-04-01 | 2026-05-27 |
| Zonisamide Versus Propranolol in Migraine Zonisamide 50 MG, Propranolol - Migraine | Phase 3 | Unknown | Kafrelsheikh University | 600 | 2024-03-29 | 2024-04-23 |
| The Effects of Combination Zonisamide and Bupropion on Switching to an Electronic Cigarette Bupropion, Zonisamide, Placebo bupropion - Smoking Cessation | Phase 3 | Completed | Rose Research Center, LLC | 180 | 2021-12-14 | 2026-02-06 |
| Zonisamide/Bupropion Effects on Switching to Electronic Cigarettes Zonisamide, Bupropion, Halo G6 e-cigarette - Smoking Cessation | Phase 3 | Completed | Rose Research Center, LLC | 26 | 2020-05-27 | 2022-04-13 |
| Interdisciplinary Study of A Novel Anticonvulsant in Alcoholism Zonisamide, Take Control, Placebo (for Zonisamide) - Alcohol Dependence | Phase 3 | Completed | Boston University Charles River Campus | 81 | 2017-09-21 | 2023-06-18 |
| Zonisamide Treatment of Alcohol Use Disorder: an Evaluation of Efficacy and Mechanism of Action Zonisamide, Placebo - Alcohol Use Disorder | Phase 3 | Completed | Virginia Commonwealth University | 156 | 2016-10-01 | 2022-10-13 |
| Effectiveness of Zonisamide in Alcohol Dependent Veterans Zonisamide, Placebo - Alcohol Use Disorder | Phase 3 | Terminated | VA Office of Research and Development | 92 | 2015-03-01 | 2020-12-07 |
| Study of Zonisamide in Early Parkinson Disease Zonisamide, Placebo - Parkinson Disease | Phase 2 / Phase 3 | Withdrawn | Mazandaran University of Medical Sciences | 2013-02-01 | 2022-04-14 | |
| Efficacy Trial of Zonisamide for Myoclonus Dystonia zonegran, placebo - Myoclonus Dystonia | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 24 | 2012-02-01 | 2015-04-24 |
| Efficacy and Safety of Adjunctive Zonisamide in Paediatric Partial Onset Seizures (CATZ Study) Zonisamide, Placebo - Epilepsy; Paediatric Partial Onset Seizures | Phase 3 | Completed | Eisai Inc. | 207 | 2008-12-01 | 2013-05-13 |
| Assessing The Long-Term Safety And To Explore The Long-Term Efficacy Of Zonisamide As Monotherapy In Newly Diagnosed Partial Seizures Zonisamide, Carbamazepine - Epilepsy | Phase 3 | Completed | Eisai Inc. | 295 | 2008-10-01 | 2015-12-24 |
| Adjunctive Zonisamide in Primary Generalised Tonic Clonic Seizures Zonisamide, Placebo - Epilepsy | Phase 3 | Terminated | Eisai Limited | 21 | 2008-08-01 | 2017-03-14 |
| A Study to Assess the Efficacy and Safety of Adjunctive Zonisamide in Paediatric Partial Onset Seizures (CATZ Extension Study) Zonisamide - Partial Seizures | Phase 3 | Completed | Eisai Limited | 144 | 2008-07-01 | 2016-01-25 |
| Efficacy and Safety of Adjunctive Zonisamide in Myoclonic Seizures Associated With Idiopathic Generalised Epilepsy Zonisamide, Placebo - Epilepsy | Phase 3 | Terminated | Eisai Limited | 10 | 2008-06-01 | 2015-12-24 |
| A Study of Zonisamide to Prevent Olanzapine-Associated Weight Gain zonisamide, olanzapine, Zonisamide - Weight Gain | Phase 3 | Completed | Lindner Center of HOPE | 42 | 2008-01-01 | 2012-04-13 |
| A Double-blind Study to Compare the Efficacy and Safety of Zonisamide and Carbamazepine as Monotherapy, in Newly Diagnosed Partial Epilepsy Zonisamide, Carbamazepine - Epilepsy | Phase 3 | Completed | Eisai Inc. | 583 | 2007-05-01 | 2015-12-24 |
| Assessment of Safety and Efficacy of Therapy for the Prevention of Weight Gain Associated With Olanzapine olanzapine, amantadine, metformin - Schizophrenia, Schizoaffective Disorders | Phase 3 | Completed | Eli Lilly and Company | 199 | 2006-11-01 | 2009-10-06 |
| Evaluating the Efficacy and Safety of Zonisamide in the Treatment of Partial Seizures Zonisamide, Placebo - Partial Seizures | Phase 3 | Completed | Eisai Inc. | 240 | 2006-09-01 | 2014-08-15 |
| A Study for Evaluating the Efficacy and Safety of Zonisamide and Lamotrigine (Lamictal) for Subjects With Refractory Simple Partial, Complex Partial or Partial With Secondary Generalized Seizures Zonisamide, Lamotrigine - Epilepsy | Phase 3 | Completed | Eisai Inc. | 64 | 2006-03-01 | 2013-05-20 |
| Zonegran in the Treatment of Binge Eating Disorder Associated With Obesity Zonegran, sugar pill - Binge Eating Disorder Associated With Obesity | Phase 3 | Completed | Lindner Center of HOPE | 60 | 2005-08-01 | 2011-06-22 |
Showing 20 of 21. Sign in to see all of them.
Epilepsy (8) · Seizures (4) · Alcoholism (3) · Alcoholic Intoxication (2) · Drinking Behavior (2) · Migraine Disorders (2) · Psychotic Disorders (2) · Smoking Cessation (2) · Vaping (2) · Binge-Eating Disorder (1) · Bipolar Disorder (1) · Epilepsy, Complex Partial (1) · Feeding and Eating Disorders (1) · Movement Disorders (1) · Myoclonic dystonia (1)
Eisai Inc. (6) · Eisai Limited (3) · Kafrelsheikh University (2) · Lindner Center of HOPE (2) · Rose Research Center, LLC (2) · Assistance Publique - Hôpitaux de Paris (1) · Boston University Charles River Campus (1) · Eli Lilly and Company (1) · Mazandaran University of Medical Sciences (1) · VA Office of Research and Development (1) · Virginia Commonwealth University (1)
United States (9) · Hungary (6) · Poland (5) · Russia (5) · Australia (4) · Estonia (4) · France (4) · Germany (4) · Italy (4) · Serbia (4) · Ukraine (4) · Lithuania (3) · South Korea (3) · Spain (3) · China (2)
Albert Arias, MD (1) · Albert J Arias, MD (1) · David H Barlow, PhD (1) · Di Hong (1) · Emmanuel Roze (1) · Joanna Segieth (1) · Joanna Segieth, PhD (1) · Masoud Etemadifar (1) · Michel Baulac (1) · Rob Van Maanen (1) · Rob van Maanen, M.D. (1) · Rob van Maanen, M.D., MFPM (1) · Susan L McElroy, MD (1) · Susan McElroy, MD (1)
PMID 11914403, PMID 12807523, PMID 8984084, PMID 17194267, PMID 20840778, PMID 21672497, PMID 22367654, PMID 22683226, PMID 37230961, PMID 39306870
2008 (1), R01AA024466 (1)