15 completed, 1 terminated. 9 Phase 3, 2 Phase 4, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 9 | Completed 9 |
| Phase 4 | 2 | Completed 1, Terminated 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Completed 1 |
Follow Epilepsy, Complex Partial: new trials by email Literature Review of Epilepsy, Complex Partial trials Research Report on Epilepsy, Complex Partial
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Neural Correlates of Cognition and Mood Behavioral testing - Epilepsy, Complex Partial | Completed | University of Minnesota | 30 | 2018-03-28 | 2022-09-10 | |
| Bioavailability, Safety, and Tolerability of BIS-001 ER BIS-001 ER - Epilepsy, Complex Partial | Phase 1 | Completed | Supernus Pharmaceuticals, Inc. | 8 | 2017-05-22 | 2018-01-18 |
| Effect on Anxiety in Partial Epilepsy Patients Treated With Pregabalin Pregabalin - Epilepsy, Complex Partial | Phase 4 | Terminated | Northeast Regional Epilepsy Group | 4 | 2010-04-01 | 2017-09-14 |
| A Treatment Use Protocol for Subjects Continuing on From the Open-label Extension 0601 ganaxolone - Epilepsy, Complex Partial | Phase 2 | Completed | Marinus Pharmaceuticals | 11 | 2009-10-01 | 2022-09-07 |
| Sabril Patient Registry Sabril® - Infantile Spasms, Refractory Complex Partial Seizures in Adults | Completed | Lundbeck LLC | 9423 | 2009-08-01 | 2016-07-29 | |
| An Open-Label Extension Study of the Safety and Tolerability of Carisbamate as Add-On Therapy in Patients With Partial Onset Seizures placebo, carisbamate - Epilepsy, Partial, Motor, Epilepsy, Complex Partial | Phase 3 | Completed | SK Life Science, Inc. | 403 | 2009-01-01 | 2013-06-18 |
| A Study of the Effectiveness, Safety, and Tolerability of Carisbamate as Add-On Therapy in Patients With Partial Onset Seizures. Carisbamate, placebo - Epilepsy, Partial, Motor, Epilepsy, Complex Partial | Phase 3 | Completed | SK Life Science, Inc. | 547 | 2009-01-01 | 2013-01-24 |
| Comparative Study Of Pregabalin And Gabapentin As Adjunctive Therapy In Subjects With Partial Seizures Pregabalin, Gabapentin - Epilepsy, Partial Seizure Disorder | Phase 4 | Completed | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | 482 | 2008-02-01 | 2021-01-22 |
| Pregabalin Versus Levetiracetam In Partial Seizures pregabalin, levetiracetam - Partial Seizures | Phase 3 | Completed | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | 509 | 2007-10-01 | 2021-01-28 |
| An Open-Label Extension Study to Evaluate the Safety and Tolerability of RWJ 333369 as Adjunctive Therapy in Patients 16 Years and Older With Partial Onset Seizures. carisbamate - Epilepsy, Complex Partial Seizures | Phase 3 | Completed | SK Life Science, Inc. | 991 | 2007-02-01 | 2013-06-18 |
| A Study of the Efficacy and Safety of RWJ-333369 as add-on Therapy in the Treatment of Partial Onset Seizures. RWJ-333369 - Epilepsy, Epilepsy, Focal | Phase 3 | Completed | SK Life Science, Inc. | 563 | 2006-11-01 | 2012-06-18 |
| A Study of the Efficacy and Safety of RWJ-333369 as add-on Therapy in the Treatment of Partial Onset Seizures. RWJ-333369 - Epilepsy, Epilepsy, Focal | Phase 3 | Completed | SK Life Science, Inc. | 566 | 2006-11-01 | 2012-06-20 |
| Efficacy and Safety of Diazepam in the Management of Refractory Epilepsy in Selected Patients Who Require Intermittent Medical Intervention for Acute Repetitive Seizures. Placebo, Vanquix Auto-Injector (Diazepam Injection) - Seizures, Epilepsies, Partial | Phase 3 | Completed | Pfizer | 234 | 2006-01-01 | 2016-09-23 |
| Dose Response Study of Zonegran in Patients With Newly Diagnosed Epilepsy Zonisamide - Epilepsy, Complex Partial | Phase 3 | Completed | Eisai Inc. | 165 | 2002-02-01 | 2011-07-18 |
| Pregabalin Open-Label Extension Trial in Patients With Partial Seizures Pregabalin - Epilepsies, Partial, Epilepsy, Complex Partial | Phase 3 | Completed | Pfizer | 300 | 2001-09-01 | 2006-07-24 |
| Effect of Vigabatrin on Brain Blood Flow and Glucose Metabolism Epilepsy, Epilepsy, Complex Partial | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 20 | 1994-10-01 | 2008-03-04 |
Seizures (11) · Epilepsies, Partial (9) · Epilepsy (9) · Epilepsy, Partial, Motor (2) · Epilepsy, Generalized (1) · Spasms, Infantile (1)
Brain Diseases (16) · Central Nervous System Diseases (16) · Nervous System Diseases (16) · Neurologic Manifestations (11) · Pathological Conditions, Signs and Symptoms (11) · Signs and Symptoms (11) · Epilepsies, Partial (7) · Epilepsy (7) · Epilepsy, Generalized (1) · Epileptic Syndromes (1)
S-2-O-carbamoyl-1-o-chlorophenyl-ethanol (5) · Pregabalin (4) · Diazepam (1) · Gabapentin (1) · Levetiracetam (1) · Vigabatrin (1) · Zonisamide (1) · ganaxolone (1) · huperzine A (1)
SK Life Science, Inc. (5) · Pfizer (2) · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (2) · Eisai Inc. (1) · Lundbeck LLC (1) · Marinus Pharmaceuticals (1) · National Institute of Neurological Disorders and Stroke (NINDS) (1) · Northeast Regional Epilepsy Group (1) · Supernus Pharmaceuticals, Inc. (1) · University of Minnesota (1)
United States (6) · Lithuania (3) · Costa Rica (2) · France (2) · Germany (2) · Italy (2) · Peru (2) · Spain (2) · Australia (1) · Austria (1) · Belgium (1) · Bulgaria (1) · Canada (1) · Colombia (1) · Czechia (1)
Evan Fertig, MD (1) · Stephen D Collins (1)
PMID 34870321, PMID 19863578, PMID 21320109, PMID 24111974, PMID 24902473, PMID 27521437