17 completed, 2 not yet recruiting, 2 unknown, 1 recruiting. 15 Not applicable, 3 Phase 1, 3 Phase 2, 2 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 15 | Completed 9, Not yet recruiting 2, Unknown 2, Recruiting 1, Terminated 1 |
| Phase 1 | 3 | Completed 3 |
| Phase 2 | 3 | Completed 3 |
| Phase 3 | 2 | Completed 2 |
| Phase 4 | 1 | Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Grape Impact on Human Gut Microbiome Grape Powder, Placebo Powder - Gut Microbiomes | Not applicable | Not yet recruiting | Icahn School of Medicine at Mount Sinai | 40 | 2026-10-01 | 2026-09-24 |
| Pharmacokinetic Characterization of Tartaric Acid in Humans Wine, Grape, Juice - Healthy Adult Participants, Non-smoking, Healthy Adults | Not applicable | Not yet recruiting | Fundacion Clinic per a la Recerca Biomédica | 30 | 2026-04-01 | 2026-02-06 |
| Grape Extract and Exercise Effects on Blood Pressure Grape extract (VinteraTM Premium OPC), Control (placebo) group - Exercise Response, Blood Pressure Monitoring, Ambulatory | Not applicable | Completed | University of Castilla-La Mancha | 10 | 2026-02-10 | 2026-05-06 |
| Evaluation of the Potential of Grape Consumption to Improve Muscle Strength and Cognitive Function Grape Powder - Healthy | Not applicable | Recruiting | Western New England University | 35 | 2025-09-09 | 2025-10-06 |
| The Effects of Freeze-Dried Whole Grape Powder on Chronic Disease and Cardiovascular Risk Factors-a Pilot Study Grape Powder - Healthy People | Not applicable | Completed | California State Polytechnic University, Pomona | 30 | 2023-10-10 | 2024-07-19 |
| Circadian Modulation of Grape Consumption and Oxidative Stress Response Grape - Oxidative Stress | Not applicable | Completed | Idaho State University | 32 | 2021-09-01 | 2023-05-24 |
| Cardioprotective Effects of Freeze Dried Grape Powder on Blood Pressure and Plasma Lipids/Lipoproteins Grape Powder, Placebo Powder - Cardiovascular Risk Factor | Not applicable | Terminated | University of Arizona | 16 | 2020-04-01 | 2024-02-15 |
| Impact of Grape Consumption on Brain Metabolism and Neuropsychological Performance Over 1 Year Grape Powder, Placebo Powder - Mild Cognitive Impairment | Phase 2 | Completed | University of California, Los Angeles | 32 | 2017-11-18 | 2023-02-21 |
| Effects of a Food Supplement on Cognitive and Neuropsychological Functioning in Older Adults. Vitis vinifera extract, Placebo - Cognitive Decline, Neurophysiologic Abnormality | Not applicable | Completed | Azienda Ospedaliera Universitaria Policlinico "G. Martino" | 111 | 2016-07-01 | 2018-06-26 |
| Dietary Prevention of Photodamage in Skin With Grapes Reconstituted grape powder - Non-melanoma Skin Cancer | Not applicable | Completed | University of Alabama at Birmingham | 18 | 2015-10-01 | 2019-03-08 |
| Study of the Nutraceutical Properties and Health Benefits of Traditional Components of the Mediterranean Diet Hazelnuts, Chocolate, Red wine - Obesity | Not applicable | Unknown | University of Rome Tor Vergata | 50 | 2013-05-01 | 2015-12-10 |
| Effect of Vitis Vinifera Extract on Oxidative Stress, Inflamatory Biomarkers and Hormones in High Trained Subjects grape fruit (vitis vinifera) extract in capsule with 205 mg - Athletic Injuries | Not applicable | Unknown | Rio de Janeiro State University | 55 | 2013-01-01 | 2013-06-12 |
| A Multicenter, Randomized, Double-blind Non-inferiority Trial to Evaluate the Efficacy and Safety of Entelon® Vitis vinifera extract, Calcium Dobesilate, Placebo - Diabetic Retinopathy | Phase 4 | Completed | Hanyang University | 153 | 2012-11-21 | 2019-05-24 |
| Edible Plant Exosome Ability to Prevent Oral Mucositis Associated With Chemoradiation Treatment of Head and Neck Cancer Grape extract, Lortab, Fentanyl patch, mouthwash - Head and Neck Cancer, Oral Mucositis | Phase 1 | Completed | University of Louisville | 60 | 2012-08-02 | 2022-08-09 |
| The Effects Grapes on Health Indices Grape in the form of freeze-dried whole grape powder, Grape powder placebo - Obesity, Inflammation | Not applicable | Completed | University of California, Davis | 20 | 2012-08-01 | 2017-05-30 |
| Evaluation of the Efficacy and Safety of Entelon Tab. 150mg in Patients With Osteoarthritis of Knee Enteron tab. 150mg(vitis vinifera extract 150mg) : twice daily for 12 weeks, Celebrex cap. (celecoxib 200mg) : once daily, for 12 weeks, Placebo - Knee Osteoarthritis | Phase 3 | Completed | Hanlim Pharm. Co., Ltd. | 338 | 2012-07-02 | 2019-07-02 |
| Evaluation of Botanicals for Mechanisms Related to Appetite and Fat Metabolism Placebo, Apple, Grape - Overweight, Obesity | Not applicable | Completed | Access Business Group | 90 | 2012-05-01 | 2015-01-07 |
| Impact of Grape Consumption on Brain Metabolism and Cognitive Function Grape Powder, Placebo Powder - Mild Cognitive Impairment | Phase 1 | Completed | University of California, Los Angeles | 12 | 2012-04-01 | 2014-12-04 |
| Pilot Study to Evaluate the Effect of ENI Patented Whole Grape Extract on Antioxidant Status ENI Patented Whole Grape Extract, Placebo - High Oxidation Stress, Oxidized LDL Level | Phase 1 | Completed | Ethical Naturals, Inc. | 26 | 2012-02-01 | 2012-07-04 |
| Grape Polyphenol Kinetics in Humans Grape - Healthy Volunteers | Not applicable | Completed | Janet Novotny | 16 | 2011-09-01 | 2017-05-25 |
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Cognitive Dysfunction (3) · Obesity (3) · Cardiovascular Diseases (2) · Dementia (2) · Inflammation (2) · Alzheimer Disease (1) · Athletic Injuries (1) · Brain Diseases (1) · Central Nervous System Diseases (1) · Diabetic Retinopathy (1) · Dyslipidemias (1) · Head and Neck Neoplasms (1) · Hyperglycemia (1) · Hyperlipidemias (1) · Hypertension (1)
University of California, Los Angeles (2) · Access Business Group (1) · Azienda Ospedaliera Universitaria Policlinico "G. Martino" (1) · California State Polytechnic University, Pomona (1) · Ethical Naturals, Inc. (1) · Fundacion Clinic per a la Recerca Biomédica (1) · Hanlim Pharm. Co., Ltd. (1) · Hanyang University (1) · Icahn School of Medicine at Mount Sinai (1) · Idaho State University (1) · Janet Novotny (1) · National Research Council, Spain (1) · Rio de Janeiro State University (1) · University of Alabama at Birmingham (1) · University of Arizona (1)
United States (13) · Spain (3) · Brazil (1) · Canada (1) · Italy (1) · South Korea (1)
Brittany C Adams (1) · Craig A. Elmets, MD (1) · Dale Wilson (1) · Daniel H Silverman, MD, PhD (1) · Daniel H. Silverman, MD, Ph.D. (1) · Daniel M Riche, Pharm.D. (1) · Eliot Brinton, MD (1) · Francene M Steinberg, PhD, RD (1) · Gang Fang, PhD (1) · J C Koury, PhD (1) · Janet Novotny, Ph.D. (1) · Rebecca Redman, MD (1) · Umberto Alecci, MD (1)
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