1106 completed, 258 recruiting, 244 unknown, 119 not yet recruiting. 1665 Not applicable, 93 Phase 3, 91 Phase 2, 63 Phase 4, 24 Phase 1.
Follow Usual Care: new trials by email Literature Review of Usual Care trials Research Report on Usual Care
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Antibiotics for Kidney Transplant Recipients Trimethoprim-Sulfamethoxazole (TMP-SMX), Usual Care - Kidney Transplant, Urinary Tract Infection(UTI) | Phase 4 | Not yet recruiting | University of California, San Francisco | 50 | 2028-10-01 | 2026-09-11 |
| Preventing the Transition From Acute to Persistent Disabling Low Back Pain Through Cognitive Functional Therapy Cognitive Functional Therapy (CFT), Usual Care - Acute Low Back Pain (Low Back Pain for Less Than 3 Months) | Not applicable | Not yet recruiting | University of Oulu | 461 | 2027-09-01 | 2026-10-16 |
| Know Your Pressures NYC Virtual Automated Navigator Intervention with Health Education, Usual Care - Glaucoma, Hypertension | Not applicable | Not yet recruiting | Columbia University | 7085 | 2027-07-01 | 2026-08-25 |
| SBAT for Health Equity SBAT Implementation, Usual Care - Asthma in Children | Not applicable | Not yet recruiting | University of Rochester | 300 | 2027-07-01 | 2026-10-13 |
| The IMPACT Study: Personalized Physical Therapy for Better Recovery and a Stronger Core After Hernia Surgery PT Group, Usual Care - Ventral Hernia, Ventral Incisional Hernia | Not applicable | Not yet recruiting | Thomas Jefferson University | 60 | 2027-07-01 | 2026-10-22 |
| Adapted Physical Activity for Persistent Fatigue in Patients With Inflammatory Bowel Disease in Remission Adapted Physical Activity, Usual Care - Inflammatory Bowel Diseases (IBD), Fatigue | Not applicable | Not yet recruiting | University Hospital, Grenoble | 120 | 2027-06-01 | 2026-09-11 |
| PrEPwise Pilot Among Black Women in Eastern Virginia PrEPwise, Usual care - HIV Infections, Sexually Transmitted Infection | Not applicable | Not yet recruiting | Boston University | 108 | 2027-04-01 | 2026-02-11 |
| Eye Health Intervention Study in Upper Manhattan Intervention, Usual Care - Glaucoma, Suspect, Diabetic Retinopathy | Not applicable | Withdrawn | Columbia University | 2027-04-01 | 2026-05-29 | |
| Implementation of Routine Walking Speed Measurements in Older Veterans Usual Care, FASTER - Aging, Fall Risk | Not applicable | Not yet recruiting | VA Office of Research and Development | 10500 | 2027-04-01 | 2026-04-07 |
| Preventing Harmful Alcohol Use Among Trauma Patients in Cameroon Cameroon-Adapted SBIRT, Usual Care - Alcohol Use Disorder, Alcohol-Related Injury | Not applicable | Not yet recruiting | University of Buea | 690 | 2027-03-01 | 2026-06-30 |
| Povidone-iodine Irrigation for Prevention of Intra-abdominal Abscess in Pediatric Perforated Appendicitis: a Multi-center Stepped Wedge Cluster Randomized Study Irrigation with PVI, Usual care - Acute, Perforated Appendicitis | Phase 4 | Not yet recruiting | The University of Texas Health Science Center, Houston | 1750 | 2027-03-01 | 2025-02-10 |
| Therapeutic Exercise and Education for Low Back Pain Therapeutic Exercise, Education on the self-management of low back pain, Usual Care - Low Back Pain | Not applicable | Not yet recruiting | University of Valladolid | 132 | 2027-03-01 | 2026-10-20 |
| Telehealth Intervention for Symptom Management and Adherence to Adjuvant Endocrine Therapy STRIDE, Usual Care - Hormone Receptor Positive Breast Cancer | Not applicable | Not yet recruiting | Massachusetts General Hospital | 400 | 2027-02-01 | 2026-10-07 |
| FASD Prevention R33 Intervention, Usual Care - Alcohol and Tobacco/Cannabis Use | Phase 2 | Not yet recruiting | Philadelphia College of Osteopathic Medicine | 184 | 2027-02-01 | 2026-09-18 |
| Improving HIV Prevention and Substance Use Post-Sexual Assault Services Enhanced intervention, Usual Care - HIV Infections, Substance Use | Not applicable | Not yet recruiting | The University of Texas Health Science Center, Houston | 90 | 2027-01-04 | 2025-11-05 |
| Alert-HF: Early Detection and Intervention on Atrial Fibrillation in Heart Failure Patients Implantable loop recorder, Patient-driven portable ECG monitoring, Usual Care - Heart Failure | Phase 4 | Not yet recruiting | Medisch Spectrum Twente | 258 | 2027-01-01 | 2026-09-11 |
| The Simplified Total-body Resistance Exercise for Muscular Hypertrophy for Diabetic Population (D-STORM) D-STORM Resistance Training Programme, usual care - Type 2 Diabetes Mellitus (T2DM), Sarcopenia | Not applicable | Not yet recruiting | Universiti Teknologi Mara | 56 | 2027-01-01 | 2026-06-25 |
| Nursing Intervention for Adaptation After Myocardial Revascularization Nursing Intervention Program, Usual Care - Coronary Artery Disease, Myocardial Revascularization | Not applicable | Not yet recruiting | Universidad de la Sabana | 40 | 2027-01-01 | 2026-05-08 |
| RE-SCALE: Rehabilitation Engagement and Scaled Access With eXtended Reality and Artificial Intelligence Mixed realities rehabilitation program, Usual Care - Chronic Low Back Pain (CLBP) | Not applicable | Not yet recruiting | Universitat Jaume I | 314 | 2027-01-01 | 2025-10-02 |
| Applying Navigation and Care to Help Ongoing Retention Family Navigation, Usual Care - Child Obesity | Not applicable | Not yet recruiting | University of Alberta | 252 | 2027-01-01 | 2026-09-22 |
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Motor Activity (122) · Diabetes Mellitus, Type 2 (86) · Hypertension (84) · Diabetes Mellitus (82) · Depression (71) · Heart Failure (69) · Obesity (68) · Stroke (59) · Neoplasms (57) · Cardiovascular Diseases (54) · Pulmonary Disease, Chronic Obstructive (51) · Anxiety Disorders (43) · Breast Neoplasms (43) · Chronic Pain (39) · Pain (39)
Massachusetts General Hospital (39) · The University of Texas Health Science Center, Houston (38) · University of Pittsburgh (32) · VA Office of Research and Development (32) · The Hong Kong Polytechnic University (25) · Duke University (20) · Mayo Clinic (20) · Assistance Publique - Hôpitaux de Paris (19) · McMaster University (19) · University of Alberta (19) · Johns Hopkins University (18) · University of Pennsylvania (18) · Chinese University of Hong Kong (17) · Emory University (17) · University of California, San Francisco (17)
United States (831) · Canada (148) · Spain (86) · France (75) · China (72) · United Kingdom (57) · Denmark (55) · Taiwan (49) · Italy (45) · Hong Kong (39) · Netherlands (35) · Norway (32) · Brazil (31) · Belgium (30) · Singapore (28)
Areej El-Jawahri, MD (5) · Ali MA Ismail, lecturer (4) · Christopher Sciamanna, MD, MPH (4) · Ryan Nipp, MD (4) · Carl J Stepnowsky, PhD (3) · Elaine Chu Shan Chew, MBBS (3) · Elizabeth Krans, MD (3) · Manali I Patel, MD MPH MS (3) · Marten Munneke, PhD (3) · Paolo Bonato, PhD (3) · Steven J Russell, MD PhD (3) · Suzanne Lo (3) · Alexandre Chan, PharmD (2) · Amal Fawzy, Ph.d (2)
PMID 36472416, PMID 33511633, PMID 34495549, PMID 34813082, PMID 39171639, PMID 11816692, PMID 24931572, PMID 25179289, PMID 27367766, PMID 3337862, PMID 33769555, PMID 33884617, PMID 34184251, PMID 36070134, PMID 39360568, PMID 41330401, PMID 41720282, PMID 42282195, PMID 10168262, PMID 10500021, PMID 10758967, PMID 10895844, PMID 10977018, PMID 11075528, PMID 11189801, PMID 11395238, PMID 11574710, PMID 11602124, PMID 11943046, PMID 12021425, PMID 1202204, PMID 12226033, PMID 12365965, PMID 12493255, PMID 12525530, PMID 12547745, PMID 12671209, PMID 12748029, PMID 12748199, PMID 12867348, PMID 12924684, PMID 12964174, PMID 13679526, PMID 14583691, PMID 14619349, PMID 14645769, PMID 14756604, PMID 15078651, PMID 15249089, PMID 15309575
2023 (5), 2025 (3), K12TR004908 (3), 2015 (2), KL2TR003168 (2), OT2HL156812 (2), OT2HL158287 (2), P30AG022845 (2), P30CA051008 (2), P50DA009253 (2), R01AG057714 (2), R01AG059815 (2), R01NR017018 (2), RC2AG036592 (2), RM1DA055311 (2)