66 completed, 34 unknown, 5 recruiting, 4 terminated. 115 Phase 2, 27 Phase 3, 26 Phase 1.
Follow Transcranial Direct Current Stimulation: new trials by email Literature Review of Transcranial Direct Current Stimulation trials Research Report on Transcranial Direct Current Stimulation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Remotely Administered tDCS to Improve Cognitive Function in Veterans With mTBI and PTSD Principal Investigator Transcranial direct current stimulation (tDCS), Cognitive training - Cognition, Brain Injuries | Phase 2 | Not yet recruiting | VA Office of Research and Development | 46 | 2027-05-24 | 2026-02-17 |
| tDCS for Late-Life Depression High-intensity (6 mA) transcranial direct current stimulation (tDCS) - Late Life Depression (LLD), Depression - Major Depressive Disorder | Phase 1 / Phase 2 | Recruiting | Andre Russowsky Brunoni | 20 | 2026-10-01 | 2026-09-25 |
| Investigating Central Contributions to Fatigue Using Non-invasive Brain Stimulation Transcranial alternating current stimulation (tACS), Sham treatment - Stroke, Cerebrovascular Accident (CVA) | Phase 1 / Phase 2 | Not yet recruiting | Vrije Universiteit Brussel | 120 | 2026-09-01 | 2026-05-29 |
| Superiority Trial of Aphasia-focused Rehabilitation With tDCS Stimulation tDCS - Aphasia, Broca's Aphasia | Phase 2 / Phase 3 | Recruiting | University of South Carolina | 130 | 2026-07-14 | 2026-07-21 |
| Synergistic Effect of Non-invasive Brain and Spinal Cord Stimulation tDCS, tSCS, Sham - Stroke, Spinal Cord Injury | Phase 2 | Recruiting | Centre National de la Recherche Scientifique, France | 45 | 2024-12-11 | 2026-01-12 |
| tDCS for Post-Stroke Cognitive Impairment Transcranial Dirrect Current Stimulation - Stroke, Mild Cognitive Impairment | Phase 2 | Recruiting | University of Oklahoma | 80 | 2024-09-30 | 2024-10-10 |
| Result of tDCS in ASD Children With Comorbidities Like PANDAS, Rare Genetic Diseases or Autoimmune Disorders tDCS or Transcranial Direct Current Stimulation, Risperidone, Sham tDCS - Attention, Visual Perceptual Weakness | Phase 1 / Phase 2 | Completed | Spanish Foundation for Neurometrics Development | 180 | 2024-04-01 | 2026-09-10 |
| Enhancing Modulation Effects of Baduanjin Through Neuromodulation for Knee OA BDJ, tDCS, sham tDCS - Knee Osteoarthritis | Phase 2 | Recruiting | Massachusetts General Hospital | 140 | 2024-03-05 | 2026-07-17 |
| tDCS in the Management of Post-COVID Disorders Transcranial Direct Current Stimulation (tDCS), Motor Training, Cognitive Training - Long COVID | Phase 2 | Unknown | Universidade Federal de Pernambuco | 48 | 2023-08-25 | 2024-04-24 |
| Remotely Supervised Transcranial Direct Current Stimulation (tDCS) for Primary Progressive Aphasia (PPA) Transcranial Direct Current Stimulation (tDCS), Word-Naming Activity - Primary Progressive Aphasia | Phase 2 | Completed | NYU Langone Health | 11 | 2022-12-24 | 2024-09-19 |
| A Teleheath tDCS Approach to Decrease Cannabis Use Transcranial Direct Current Stimulation (tDCS), Sham - Transcranial Direct Current Stimulation (tDCS), Mindfulness - Cannabis Use Disorder, Multiple Sclerosis | Phase 2 | Completed | NYU Langone Health | 52 | 2022-09-13 | 2025-06-24 |
| TDCS in Pediatric and Teenage Patients With Major Depressive Disorder During COVID-19 Pandemic Transcranial Direct Current Stimulation, Placebo-simulation of transcranial direct current stimulation, Fluoxetine Tablets - Major Depressive Disorder | Phase 2 / Phase 3 | Unknown | El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez | 172 | 2021-10-01 | 2021-06-04 |
| Neuromodulation in COVID-19 Patients Transcranial direct-current stimulation, Sham Transcranial direct-current stimulation - COVID-19 | Phase 1 / Phase 2 | Completed | D'Or Institute for Research and Education | 60 | 2021-08-10 | 2021-10-14 |
| Apply tACS to Alleviate Anxiety Symptoms transcranial alternating current stimulation (tACS) - Anxiety Disorders | Phase 2 | Unknown | NeuroCognitive and Behavioral Institute Clinical Research Foundation | 40 | 2021-06-01 | 2023-10-18 |
| Transcranial Direct Current Stimulation to Reduce Chronic Pelvic Pain in Endometriosis tDCS : Transcranial direct current stimulation - Endometriosis | Phase 2 | Unknown | Charite University, Berlin, Germany | 40 | 2021-01-01 | 2022-02-09 |
| Effects of tDCS on Anaerobic Power of Lower Limb Muscles Transcranial direct current stimulation - Healthy Volunteers | Phase 2 / Phase 3 | Completed | Universidade Federal do Piauí | 50 | 2021-01-01 | 2021-05-03 |
| Clinical Intervention on Cognitive Impairment of Schizophrenia With Metabolic Syndrome Omega-3 polyunsaturated fatty acids, Xbox aerobic exercise, transcranial direct current stimulation,tDCS - Schizophrenia | Phase 2 | Suspended | Shanghai Mental Health Center | 120 | 2020-10-01 | 2023-04-18 |
| Biomarkers of Response to Treatment With Frontal Cortex Stimulation for Anxious Depression transcranial direct current stimulation using a Soterix mini-CT device - Major Depressive Disorder, Anxiety | Phase 1 / Phase 2 | Terminated | Mclean Hospital | 1 | 2020-02-13 | 2021-02-12 |
| DAOIB Combined With tDCS for Early-phase Dementia DAOIB, Placebo, tDCS - Transcranial Direct Current Stimulation, Dementia | Phase 2 | Completed | Chang Gung Memorial Hospital | 97 | 2020-01-01 | 2023-01-06 |
| Imaging the Effects of Bihemispheric Transcranial Stimulation and Motor Training After Stroke. tDCS + upper limb rehabilitation, Sham tDCS + upper limb rehabilitation - Stroke | Phase 2 | Unknown | D'Or Institute for Research and Education | 24 | 2019-10-29 | 2019-12-11 |
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Stroke (23) · Depressive Disorder, Major (13) · Depression (10) · Cognitive Dysfunction (6) · Pain (6) · Schizophrenia (6) · Fibromyalgia (5) · Aphasia (4) · Bipolar Disorder (4) · Cerebral Infarction (4) · Parkinson Disease (4) · Anxiety Disorders (3) · Cerebrovascular Disorders (3) · Inflammatory Bowel Diseases (3) · Migraine Disorders (3)
The University of New South Wales (8) · Universidade Federal de Pernambuco (7) · University of Sao Paulo (7) · Federal University of Paraíba (6) · Universidade Federal do Piauí (6) · Charite University, Berlin, Germany (4) · Federal University of Espirito Santo (3) · Hospital de Clinicas de Porto Alegre (3) · University of Liege (3) · Centre Hospitalier Universitaire de Besancon (2) · D'Or Institute for Research and Education (2) · El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez (2) · Massachusetts General Hospital (2) · NYU Langone Health (2) · Northwell Health (2)
Brazil (39) · United States (26) · Australia (8) · Germany (8) · France (6) · Belgium (5) · Canada (4) · South Korea (3) · Italy (2) · Mexico (2) · Austria (1) · China (1) · Serbia (1) · Spain (1) · Switzerland (1)
Andre R Brunoni, MD (3) · Colleen Loo (2) · Erika C Rodrigues, PhD (2) · Ester M Nakamura-Palacios, MD, PhD (2) · Fernanda F Tovar-Moll, PhD (2) · Fuad Hazime, PhD (2) · Leigh Charvet, PhD (2) · Adriana Baltar, PhD (1) · Agnes Floeel, Prof MD (1) · Agnes Floel, MD (1) · Alessandra Lugaresi, MD, PhD (1) · Alexandre DaSilva, DDS, MS (1)
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1IK2RD000464-01A2 (1), 2014 (1), K01HD069504 (1), R01AG060981 (1), U01DC022447 (1), U01NS102353 (1)