14 completed, 4 unknown, 1 recruiting, 1 terminated. 6 Phase 3, 4 Phase 4, 3 Not applicable, 2 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 6 | Completed 3, Recruiting 1, Terminated 1, Unknown 1 |
| Phase 4 | 4 | Completed 2, Unknown 2 |
| Not applicable | 3 | Completed 3 |
| Phase 2 | 2 | Completed 2 |
| Phase 1 | 1 | Completed 1 |
Follow Ticagrelor 90mg: new trials by email Literature Review of Ticagrelor 90mg trials Research Report on Ticagrelor 90mg
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of Low Dose Colchicine and Ticagrelor in Prevention of Ischemic Stroke in Patients With Stroke Due to Atherosclerosis Colchicine 0.5 MG, Ticagrelor 90mg, Aspirin 75-300mg - Stroke, Stroke, Ischemic | Phase 3 | Recruiting | Assistance Publique - Hôpitaux de Paris | 2800 | 2023-05-17 | 2025-09-08 |
| Evaluation of Safety and Efficacy of Two Ticagrelor-based De-escalation Antiplatelet Strategies in Acute Coronary Syndrome Ticagrelor 90mg, Ticagrelor 60mg, Aspirin - STEMI, NSTEMI | Phase 3 | Unknown | Collegium Medicum w Bydgoszczy | 4500 | 2022-02-07 | 2023-04-21 |
| Ticagrelor Monotherapy After Stenting Ticagrelor 90mg - Acute Myocardial Infarction | Phase 2 | Completed | Vastra Gotaland Region | 200 | 2021-12-14 | 2026-03-20 |
| Efficacy of Ticagrelor Plus Aspirin in Mild Non-cardioembolic Ischemic Stroke Ticagrelor 90mg, Clopidogrel 75 mg - Ischemic Stroke, Transient Ischemic Attack | Phase 3 | Completed | Mazandaran University of Medical Sciences | 90 | 2021-08-08 | 2023-10-19 |
| Platelet Inhibition With Ticagrelor 60 mg Versus Ticagrelor 90 mg in Elderly Patients With ACS Ticagrelor 90mg, Ticagrelor 60 mg - Acute Coronary Syndrome, STEMI | Phase 3 | Completed | Federico II University | 50 | 2021-04-01 | 2022-07-07 |
| Optical Coherence Tomography-Guided PCI With Single-Antiplatelet Therapy Prasugrel 10mg, Ticagrelor 90mg - Non ST Segment Elevation Acute Coronary Syndrome | Phase 2 | Completed | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 75 | 2021-02-19 | 2023-03-06 |
| Replication of the ISAR-REACT 5 Antiplatelet Trial in Healthcare Claims Data Ticagrelor 90mg, Prasugrel 10mg - Acute Coronary Syndrome | Completed | Brigham and Women's Hospital | 28389 | 2020-10-10 | 2023-07-27 | |
| Early Versus Late Loading of Ticagrelol in Patients With STEMI Ticagrelor 90mg - Myocardial Infarction | Unknown | Assiut University | 800 | 2020-03-01 | 2020-02-12 | |
| A Study of Low and Standard-dose Ticagrelor After Intervention for ACS Patients Ticagrelor 60mg, Ticagrelor 90mg - Acute Coronary Syndrome, Coronary Stent Implantation | Phase 4 | Unknown | Shanghai Tong Ren Hospital | 2120 | 2020-02-19 | 2023-12-07 |
| Replication of the PLATO Antiplatelet Trial in Healthcare Claims Data Ticagrelor 90mg, Clopidogrel 75mg - Antiplatelet | Completed | Brigham and Women's Hospital | 27960 | 2019-09-22 | 2023-07-27 | |
| LOwer Maintenance Dose TICagrelor in Acute Coronary Syndrome Patients Undergoing Percutaneous Coronary Intervention Ticagrelor 90mg, Ticagrelor 90mg/60mg, Clopidogrel 75mg - Antiplatelet Therapy, Coronary Artery Disease | Phase 4 | Unknown | Beijing Anzhen Hospital | 225 | 2019-08-30 | 2019-08-19 |
| The Value of Screening for HPR in Patients Undergoing Lower Extremity Arterial Endovascular Interventions Point of care screening for HPR, Ticagrelor 90mg - Peripheral Artery Disease, Clopidogrel, Poor Metabolism of | Phase 3 | Terminated | Marissa Jarosinski | 31 | 2019-08-09 | 2026-07-06 |
| Ticagrelor and Clopidogrel on Platelet Effects in Chinese Patients With Stable Coronary Artery Disease Ticagrelor 90mg, Clopidogrel 75mg - Platelet Reactivity | Phase 4 | Completed | First Affiliated Hospital of Harbin Medical University | 50 | 2019-07-02 | 2022-01-11 |
| Chronic Kidney Disease (CKD) Platelet Study Ticagrelor 90mg, Clopidogrel 75mg, Aspirin 81 mg - Chronic Kidney Diseases, Heart Attack | Phase 3 | Completed | University of Arkansas | 76 | 2018-11-01 | 2022-12-29 |
| Ticagrelor Compared to Clopidogrel in Acute Coronary Syndromes Ticagrelor 90mg, Clopidogrel 75mg, acetylsalicylic acid (ASA) 81mg - Acute Coronary Syndrome | Phase 4 | Completed | McGill University Health Centre/Research Institute of the McGill University Health Centre | 1038 | 2018-10-01 | 2023-11-03 |
| A Study of the Effect of Epinephrine on Platelet Reactivity in Subjects Treated With Ticagrelor Ticagrelor 90mg, Epinephrine, Metoprolol - Healthy Volunteers | Phase 1 | Completed | Vastra Gotaland Region | 10 | 2018-02-28 | 2018-05-11 |
| Effect of Diabetes and Hepatic Enzymes Mutation on Clopidogrel VS Ticagrelor Activity in Myocardial Infarction (MI) Patients Undergoing Primary Percutaneous Coronary Intervention (PCI) Clopidogrel, Ticagrelor 90mg - Myocardial Infarction | Completed | Cairo University | 1022 | 2017-04-15 | 2019-01-14 | |
| In Vitro Pharmacodynamic Effects of Cangrelor in Ticagrelor Treated Patients Ticagrelor 180mg, Ticagrelor 90mg - Coronary Artery Disease | Not applicable | Completed | University of Florida | 60 | 2014-04-01 | 2017-04-04 |
| Pharmacodynamic Evaluation of Switching From Prasugrel to Ticagrelor Ticagrelor 180mg, Prasugrel 10mg, Ticagrelor 90mg - Coronary Artery Disease, Acute Coronary Syndrome | Not applicable | Completed | University of Florida | 82 | 2014-03-01 | 2024-07-03 |
| Impact of Ticagrelor Re-load on Pharmacodynamic Profiles Ticagrelor 180mg, Ticagrelor 90mg - Coronary Artery Disease | Not applicable | Completed | University of Florida | 60 | 2013-01-01 | 2015-06-10 |
Acute Coronary Syndrome (6) · Coronary Artery Disease (6) · Myocardial Infarction (6) · Ischemic Stroke (3) · Angina, Unstable (2) · Non-ST Elevated Myocardial Infarction (2) · ST Elevation Myocardial Infarction (2) · Stroke (2) · Atherosclerosis (1) · Cardiovascular Diseases (1) · Cerebral Infarction (1) · Coronary Disease (1) · Heart Diseases (1) · Ischemic Attack, Transient (1) · Peripheral Arterial Disease (1)
University of Florida (3) · Brigham and Women's Hospital (2) · Vastra Gotaland Region (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Assistance Publique - Hôpitaux de Paris (1) · Assiut University (1) · Beijing Anzhen Hospital (1) · Cairo University (1) · Collegium Medicum w Bydgoszczy (1) · Federico II University (1) · First Affiliated Hospital of Harbin Medical University (1) · Marissa Jarosinski (1) · Mazandaran University of Medical Sciences (1) · McGill University Health Centre/Research Institute of the McGill University Health Centre (1) · Shanghai Tong Ren Hospital (1)
United States (7) · China (3) · Sweden (2) · Canada (1) · Egypt (1) · France (1) · Iran (1) · Italy (1) · Netherlands (1) · Poland (1)
Anders Jeppsson, MD,PhD,Prof (1) · Athena Sharifi-Razavi (1) · Dominick Angiolillo (1) · Dominick Angiolillo, MD, PhD (1) · Dominick J Angiolillo, MD, PhD (1) · Eliano Navarese, MD, PhD (1) · Giovanni Esposito, MD, PhD (1) · Hany R. Maher (1) · Jacek Kubica, MD, PhD (1) · Jain Nishank, MD (1) · James Brophy, MD, PhD (1) · Junbo Ge, Doctor (1) · Lei Hou, Doctor (1) · Shirley Wang, PhD (1)
PMID 26117466, PMID 27013060, PMID 30780166, PMID 32675750, PMID 33327727, PMID 34096012, PMID 35048203, PMID 35224730, PMID 35248132, PMID 36682595, PMID 40164463