115 completed, 44 unknown, 12 recruiting, 9 terminated. 189 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 189 | Completed 115, Unknown 44, Recruiting 12, Terminated 9, Withdrawn 6, Active not recruiting 2, Not yet recruiting 1 |
Follow Ticagrelor: new trials by email Literature Review of Ticagrelor trials Research Report on Ticagrelor
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Short-Term Dual Antiplatelet Therapy With Early Transi-tion to Low-dose Antiplatelet Monotherapy Using Ti-cagRelor in Chronic Coronary Artery Disease Ticagrelor 60 mg, clopidogrel 75 mg - Chronic Coronary Syndrome | Phase 4 | Not yet recruiting | University of Messina | 1000 | 2026-11-01 | 2026-09-15 |
| Dual Antiplatelet Therapy Strategies After Acute Myocardial Infarction Undergoing PCI: Prasugrel vs Ticagrelor & 12 Months vs 1-3 Months Prasugrel, Ticagrelor - Myocardial Infarction (MI) | Phase 4 | Recruiting | Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz | 8100 | 2026-09-02 | 2026-09-09 |
| IndObufen Versus asPirin After Coronary Drug-eluting Stent implantaTION in Elderly Patients With Acute Coronary Syndrome Indobufen, Aspirin, Ticagrelor - Coronary Artery Disease, Antiplatelet Drugs | Phase 4 | Recruiting | Shanghai Zhongshan Hospital | 2846 | 2025-05-19 | 2026-03-12 |
| Switching From Dual Antiplatelet Therapy to Monotherapy With Potent P2Y12 Inhibitors Ticagrelor 90 mg, Prasugrel 10 mg - Coronary Artery Disease | Phase 4 | Recruiting | University of Florida | 48 | 2025-01-08 | 2026-02-05 |
| Colonoscopy and Antiplatelet Therapy Trial Aspirin, P2Y12 inhibitor (clopidogrel, ticagrelor, prasugrel) - Coronary Arterial Disease (CAD), Peripheral Vascular Disease | Phase 4 | Unknown | Ochsner Health System | 100 | 2024-10-01 | 2024-09-25 |
| Ticagrelore Alone Post PCI aspirin 80 mg and clopidogrel 75 mg daily, Ticagrelor 90 MG - Coronary Artery Disease | Phase 4 | Recruiting | Shiraz University of Medical Sciences | 5400 | 2024-08-01 | 2025-05-21 |
| Century Clot-Guided Prophylactic Rivaroxaban for Post STEMI Complicating Left Ventricular Thrombus NOAC+DAPT, DAPT - STEMI - ST Elevation Myocardial Infarction | Phase 4 | Recruiting | Zunyi Medical College | 374 | 2024-04-01 | 2024-03-19 |
| Effects of Low-dose Ticagrelor vs. Clopidogrel in Stable Patients Undergoing Elective Percutaneous Coronary Intervention Ticagrelor 60mg, Clopidogrel - Coronary Artery Disease | Phase 4 | Recruiting | University of Florida | 50 | 2024-04-01 | 2026-02-05 |
| Pharmacodynamic Outcomes in CCS Patients Treated With an Individualized Treatment Strategy CYP2C19 genotype guided P2Y12 monotherapy, Clopidogrel - Coronary Artery Disease, Platelet Reactivity | Phase 4 | Unknown | St. Antonius Hospital | 88 | 2024-01-23 | 2024-01-26 |
| Pharmacodynamic and Short-term Effects of Half-dose Ticagrelor With or Without Aspirin vs DAPT From Day of PCI in CCS Aspirin 100 mg + clopidogrel (300 mg load → 75 mg daily) ×6 months, then aspirin monotherapy, Aspirin 100 mg + ticagrelor (90 mg load → 45 mg twice daily) ×6 months, then aspirin monotherapy, Ticagrelor (90 mg load → 45 mg twice daily) monotherapy; aspirin stopped at day 2 after randomisation; continued indefinitely - Coronary Heart Disease | Phase 4 | Completed | Kaohsiung Veterans General Hospital. | 54 | 2024-01-03 | 2026-09-14 |
| Ticagrelor Single Antiplatelet Therapy in Patients With High Risk of Bleeding After DCB for Coronary Small Vessel Disease Ticagrelor, Clopidogrel, Aspirin - Coronary Heart Disease | Phase 4 | Unknown | Fu Wai Hospital, Beijing, China | 292 | 2023-11-15 | 2023-10-18 |
| TISSARA Trial: Ticagrelor Intervention to Reduce Stent Thrombosis and Acute MI Risk Ticagrelor - STEMI - ST Elevation Myocardial Infarction, Stent Thrombosis | Phase 4 | Completed | National Institute of Cardiovascular Diseases, Pakistan | 1727 | 2023-08-24 | 2024-10-31 |
| Prospective, Post-registration, Interventional, Randomized, in Parallel Groups, Multicenter Eurasian Clinical Study of DERIVO®/DERIVO® Mini Aneurysm Embolization Device, Europe-Asia ticagrelor (tablets, 180 mg) or prasugrel (tablets, 10 mg)., combination of clopidogrel (tablets, 75 mg) and acetylsalicylic acid (ASA, tablets, 100 mg) or a combination of ticagrelor (tablets, 180 mg) and ASA (tablets, 100 mg). - Intracranial Aneurysm | Phase 4 | Recruiting | Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health | 640 | 2023-08-17 | 2024-05-06 |
| Ticagrelor De-escalation Strategy in AMI Patients De-escalation strategy, Conventional strategy - Acute Myocardial Infarction | Phase 4 | Recruiting | Dong-A University | 2312 | 2023-03-27 | 2025-10-01 |
| Tailoring Bleeding Reduction Approaches in Patients Undergoing PCI aspirin plus clopidogrel, prasugrel or ticagrelor - Coronary Artery Disease | Phase 4 | Completed | University of Florida | 84 | 2023-02-15 | 2026-10-28 |
| Platelet Sub-study of the Neomindset Trial Dual antiplatelet therapy: Acetylsalicylic acid + ticagrelor OR Acetylsalicylic acid + prasugrel, Monotherapy: Ticagrelor alone OR Prasugrel alone - Acute Coronary Syndrome | Phase 4 | Active not recruiting | Hospital Israelita Albert Einstein | 48 | 2023-02-06 | 2025-04-08 |
| OPTIMIZE-APT: Tailored Versus Conventional Antiplatelet Therapy After Intravascular Imaging-guided Drug-eluting Stent Implantation aspirin - Coronary Artery Disease | Phase 4 | Recruiting | Asan Medical Center | 3944 | 2022-10-21 | 2026-09-17 |
| Switching From Ticagrelor to Prasugrel in Patients With Acute Coronary Syndrome Prasugrel 10 mg p.o, Ticagrelor 90 mg - Acute Coronary Syndrome | Phase 4 | Completed | Vastra Gotaland Region | 17095 | 2022-02-01 | 2026-07-08 |
| Dual Antiplatelet Therapy in Patients With Clopidogrel Resistance Following Off-Pump Coronary Artery Bypass Ticagrelor, Clopidogrel - Multi Vessel Coronary Artery Disease | Phase 4 | Unknown | Yonsei University | 204 | 2022-02-01 | 2021-12-22 |
| Single Antiplatelet Treatment With Ticagrelor or Aspirin After Transcatheter Aortic Valve Implantation Ticagrelor 60mg - Severe Aortic Valve Stenosis, Aortic Valve Stenosis | Phase 4 | Recruiting | Fundacin Biomedica Galicia Sur | 1206 | 2022-01-21 | 2026-07-28 |
Showing 20 of 189. Sign in to see all of them.
Coronary Artery Disease (55) · Acute Coronary Syndrome (44) · Myocardial Infarction (21) · ST Elevation Myocardial Infarction (20) · Cardiovascular Diseases (11) · Thrombosis (11) · Diabetes Mellitus (10) · Angina, Unstable (9) · Coronary Disease (8) · Atrial Fibrillation (5) · Diabetes Mellitus, Type 2 (5) · Non-ST Elevated Myocardial Infarction (5) · Atherosclerosis (4) · Heart Diseases (4) · Hemorrhage (4)
University of Florida (13) · AstraZeneca (10) · University of Patras (9) · First Affiliated Hospital of Harbin Medical University (6) · Collegium Medicum w Bydgoszczy (5) · Medical University of Vienna (3) · Shanghai Tong Ren Hospital (3) · Yonsei University (3) · Attikon Hospital (2) · Beijing Anzhen Hospital (2) · Deutsches Herzzentrum Muenchen (2) · Dong-A University (2) · Faculty Hospital Kralovske Vinohrady (2) · Federal University of São Paulo (2) · Fu Wai Hospital, Beijing, China (2)
United States (43) · China (36) · South Korea (16) · Greece (12) · Canada (10) · Poland (10) · Netherlands (9) · Spain (9) · United Kingdom (8) · Germany (7) · Italy (7) · Austria (6) · Brazil (5) · Denmark (3) · France (3)
Dominick J Angiolillo, MD, PhD (5) · Dominick J Angiolillo, MD,PhD (4) · Dimitrios Alexopoulos, MD (3) · Jacek Kubica, MD., PhD. (3) · Juan J Badimon, PhD (3) · Chunjian Li, Ph.D (2) · David Antoniucci, MD (2) · Dominick Angiolillo (2) · Francesco Franchi, MD (2) · Glenn Carlson, MD (2) · Haiyan Qian, MD, PhD (2) · Jeffrey Berger, MD (2) · Michael Wolzt, Prof. MD (2) · Yue Li, PhD (2) · Abdul Hakeem, MD (1)
PMID 35224730, PMID 40875095, PMID 19717846, PMID 19923168, PMID 30621974, PMID 11519503, PMID 21873419, PMID 23491524, PMID 23500251, PMID 24291273, PMID 24768873, PMID 25175921, PMID 31475799, PMID 33032710, PMID 11786451, PMID 12020339, PMID 12435254, PMID 12796140, PMID 12832332, PMID 14504252, PMID 14517152, PMID 14602724, PMID 15596563, PMID 15603245, PMID 15738352, PMID 16046311, PMID 16271642, PMID 16286166, PMID 16339499, PMID 16403930, PMID 16476694, PMID 16495286, PMID 16551712, PMID 17109936, PMID 17132052, PMID 17261652, PMID 17374814, PMID 17418288, PMID 17936152, PMID 17980251, PMID 17982182, PMID 18297550, PMID 18574088, PMID 19174428, PMID 19267766, PMID 19336636, PMID 19349321, PMID 19482214, PMID 19915221, PMID 19915222
2014 (2), 1OT2HL156812-01 (1), 2015 (1), 2016 (1), 2018 (1), 2019 (1), 2023 (1), U01HL128606 (1)