20 completed, 6 unknown, 3 recruiting, 2 terminated. 33 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 33 | Completed 20, Unknown 6, Recruiting 3, Terminated 2, Enrolling by invitation 1, Not yet recruiting 1 |
Follow Synbiotic: new trials by email Literature Review of Synbiotic trials Research Report on Synbiotic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effect of a Synbiotic on Intestinal Barrier Function and Microbiota Modulation in Middle-aged to Elderly Individuals With Excessive Body Weight Synbiotic, Placebo - Gastrointestinal Microbiome (Focus), Gastrointestinal Symptoms | Not applicable | Recruiting | Chr Hansen - part of Novonesis | 90 | 2026-03-18 | 2026-04-15 |
| Probiotic and Prebiotic Supplementation in Peritoneal Dialysis Patients Synbiotic, Placebo - Chronic Kidney Disease (Stages 4 and 5), Peritoneal Dialysis (PD) | Not applicable | Recruiting | Hospital Universitario Dr. Jose E. Gonzalez | 60 | 2025-10-03 | 2026-07-10 |
| The Effects of a Commercially Available Synbiotic on the Gut Microbiome and Cardiometabolic Health Synbiotic, Placebo - Hypertension, Gut Dysbiosis | Not applicable | Completed | Southern Utah University | 47 | 2025-09-01 | 2026-07-29 |
| Therapeutic Potential of a Synbiotic to Improve Mental Health in Subjects With Obesity. Synbiotic, Placebo - Obese Patients (BMI ≥ 30 kg/m²), Anxiety | Not applicable | Recruiting | Celia Bañuls | 120 | 2025-04-15 | 2026-09-08 |
| NapBiome: Targeting Gut Microbiota and Sleep Rhythm to Improve Developmental and Behavioral Outcomes in Early Childhood Synbiotic, Placebo - Sleep Problem, Neurobehavioral Manifestations | Not applicable | Not yet recruiting | Petra Zimmermann | 380 | 2025-03-01 | 2025-02-20 |
| Evaluating the Impact of Synbiotic Supplementation on Infants and Toddlers Synbiotic Supplement, Lactose (inactive placebo) - Gastrointestinal Tolerance of Probiotics in Infants | Not applicable | Completed | Persephone Biosciences | 110 | 2025-01-01 | 2026-08-25 |
| Synbiotic Supplementation in Cyclists Synbiotic, Placebo - Exercise Endurance | Not applicable | Completed | University of Calgary | 22 | 2024-07-15 | 2026-05-01 |
| Impact of Nutritional Intervention With Probiotics and Prebiotics on Obesity. Probiotic, Prebiotic, Synbiotic - Obesity and Overweight, Obesity, Morbid | Not applicable | Enrolling by invitation | Fundación Pública Andaluza para la Investigación Biomédica Andalucía Oriental | 230 | 2024-02-01 | 2025-04-11 |
| The Effects of Synbiotic on Cardiovascular and Bone Metabolism Markers in Transplanted Kidney Patients synbiotic, placebo - Transplanted Kidney | Not applicable | Unknown | National Nutrition and Food Technology Institute | 44 | 2023-12-01 | 2023-12-07 |
| Efficacy of Synbiotic Supplementation on IL-10, TGF-B and Disease Activity in Systemic Lupus Erythematosus Patients Synbiotic, Placebo - Systemic Lupus Erythematosus | Not applicable | Completed | Universitas Sriwijaya | 36 | 2023-12-01 | 2025-07-02 |
| The Role of Synbiotics in Modulating Host Physiology Via the Gut Microbiome Synbiotic - Healthy | Not applicable | Completed | Elizabeth Simpson | 40 | 2023-07-24 | 2025-05-15 |
| Mitigating Infectious Morbidity and Growth Deficits in HIV Exposed Uninfected infanTs With Human Milk Oligosaccharides Synbiotic, Maltodextrin - HIV, Infant Morbidity | Not applicable | Completed | Columbia University | 140 | 2022-06-02 | 2026-07-01 |
| Combined Gut-brain Therapy for Children With Autism Synbiotic, Gut-directed Hypnotherapy - Autism Spectrum Disorder, Functional Gastrointestinal Disorders | Not applicable | Completed | The University of Queensland | 40 | 2021-12-01 | 2023-09-06 |
| Synbiotics and Post-op Crohn's Disease Synbiotic, Digestible Maltodextrin - Crohn's Disease | Not applicable | Terminated | University of Alberta | 4 | 2021-07-15 | 2024-01-19 |
| Effect of Synbiotic L. Fermentum Strains on Body Fat Mass synbiotic, probiotic, placebo - Weight, Body | Not applicable | Unknown | Slimbiotics GmbH | 180 | 2021-06-08 | 2022-06-06 |
| The Effect of Synbiotics on the Upper Respiratory Tract Infection Synbiotic, Placebo - Upper Respiratory Tract Infection, Gut Microbiota | Not applicable | Completed | Huazhong University of Science and Technology | 58 | 2020-10-05 | 2021-07-14 |
| Clinical Study on the Effect of a Synbiotic on Body Fat Mass synbiotic, microcrystalline cellulose - Type 2 Diabetes, Metabolic Syndrome | Not applicable | Completed | Slimbiotics GmbH | 120 | 2020-05-13 | 2022-06-01 |
| PROBESITY-2: Synbiotics in Pediatric Obesity Synbiotic - Obesity, Childhood, Obesity, Adolescent | Not applicable | Completed | Eskisehir Osmangazi University | 61 | 2019-06-01 | 2022-01-11 |
| Effects of Triphala and VSL#3 Probiotic Supplementation on Stool Microbiome Profiles and Inflammation Synbiotic, Probiotic, Placebo - Human Microbiome | Not applicable | Terminated | University of California, San Diego | 75 | 2019-02-01 | 2023-07-06 |
| Effect of Synbiotic on Immune Response, Gut Permeability and Microbiota in Patient With Connective Tissue Disease Synbiotic, Placebo - Connective Tissue Diseases | Not applicable | Completed | Fakultas Kedokteran Universitas Indonesia | 46 | 2017-10-01 | 2019-03-12 |
Showing 20 of 33. Sign in to see all of them.
Obesity (8) · Inflammation (4) · Metabolic Syndrome (3) · Overweight (3) · Anxiety Disorders (2) · Body Weight (2) · Obesity, Morbid (2) · Renal Insufficiency, Chronic (2) · Autism Spectrum Disorder (1) · Autistic Disorder (1) · Breast Feeding (1) · Connective Tissue Diseases (1) · Constipation (1) · Crohn Disease (1) · Depressive Disorder (1)
University of Reading (3) · Slimbiotics GmbH (2) · Universidade Federal de Santa Catarina (2) · Celia Bañuls (1) · Chr Hansen - part of Novonesis (1) · Columbia University (1) · Elizabeth Simpson (1) · Eskisehir Osmangazi University (1) · Fakultas Kedokteran Universitas Indonesia (1) · Federico II University (1) · Fundación Pública Andaluza para la Investigación Biomédica Andalucía Oriental (1) · Hospital Universitario Dr. Jose E. Gonzalez (1) · Hospital de Clinicas de Porto Alegre (1) · Huazhong University of Science and Technology (1) · National Nutrition and Food Technology Institute (1)
United Kingdom (5) · United States (5) · Brazil (3) · Canada (2) · Germany (2) · Indonesia (2) · Spain (2) · Australia (1) · Austria (1) · Chile (1) · China (1) · Ireland (1) · Italy (1) · Mexico (1) · South Africa (1)
Amrita Vijay, PhD (1) · Bruna Guida, MD (1) · Christiane Laue, Dr. med. (1) · Christine T Peterson, PhD (1) · Christopher D Byrne, MBBCh, PhD (1) · Cleber Kruel, Doctor (1) · Ener C Dinleyici, MD (1) · Erasmo Trindade, PhD (1) · Glenn R Gibson, BSc, PhD (1) · Helmut Essl (1) · Karen L Madsen, PhD (1) · Kathleen Angkustsiri, MD (1) · Leanne K Mitchell, B.HlthSc (Hons) (1) · Liegang Liu, PhD (1)
PMID 36126902, PMID 24743428, PMID 25909598, PMID 26602219, PMID 29787859, PMID 31987796, PMID 35845797, PMID 36585139, PMID 37293067, PMID 37474971, PMID 40032396, PMID 41094562
R01HD105492 (1)