36 terminated. 36 Phase 2, 5 Phase 3, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 36 | Terminated 36 |
| Phase 3 | 5 | Terminated 5 |
| Phase 1 | 2 | Terminated 2 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Treatment of Pneumocystis in COPD (the TOPIC Study) Trimethoprim Sulfamethoxazole, Placebo - COPD Exacerbation Acute | Phase 1 / Phase 2 | Terminated | Corewell Health East | 1 | 2022-09-28 | 2023-11-29 |
| Troriluzole or Placebo Plus Ipi Plus Nivo in Mel Brain Mets Ipilimumab, Nivolumab, Troriluzole - Melanoma, Metastatic Melanoma | Phase 2 | Terminated | Dana-Farber Cancer Institute | 1 | 2021-06-30 | 2024-03-26 |
| Study of Immunomodulation Using Naltrexone and Ketamine for COVID-19 Naltrexone, Ketamine, Placebo - COVID-19, Acute Respiratory Distress Syndrome | Phase 2 | Terminated | Corewell Health East | 70 | 2020-04-29 | 2022-01-26 |
| Prevention and Management of Intravesical BCG-related Lower Urinary Tract Symptoms Pentosan Polysulfate Na 100Mg Cap, Placebo oral capsule - Lower Urinary Tract Symptoms, Bladder Carcinoma | Phase 2 | Terminated | Sir Mortimer B. Davis - Jewish General Hospital | 3 | 2019-05-03 | 2022-03-04 |
| Gemcitabine and Capecitabine With or Without T-ChOS as Adjuvant Therapy for Patients With Resected Pancreatic Cancer T-ChOS, Gemcitabine, Placebo - Pancreatic Cancer | Phase 2 | Terminated | Herlev Hospital | 21 | 2016-11-01 | 2018-07-10 |
| Metformine and CC Compared With Placebo and CC for Induction Ovulation in PCOS Patients With Insulin Resistant metformine, placebo, clomiphene citrate - Polycystic Ovary Syndrome, Hyperandrogenism | Phase 2 | Terminated | Semnan University of Medical Sciences | 388 | 2015-11-01 | 2024-04-25 |
| Metformin for Reduction of Paclitaxel-Related Neuropathy in Patients With Breast Cancer Metformin, Placebo, Questionnaires - Breast Cancer | Phase 2 | Terminated | M.D. Anderson Cancer Center | 1 | 2015-10-01 | 2017-08-17 |
| Ondansetron for the Treatment of Heavy Drinking Among Emerging Adults Ondansetron, Placebo, BASICS Plus - Alcohol Abuse, Alcoholism | Phase 2 | Terminated | University of Maryland, Baltimore | 74 | 2015-09-01 | 2023-05-26 |
| Effectiveness of Ranolazine on Reducing Chest Pain in Patients With Blockage But no Stents Ranolazine, Sugar pill - Angina | Phase 2 | Terminated | North Florida Foundation for Research and Education | 5 | 2015-08-01 | 2019-06-11 |
| Metformin in Non Small Cell Lung Cancer (NSCLC) Metformin, Placebo, Stereotactic body Radiotherapy (SBRT) - Lung Cancer | Phase 2 | Terminated | M.D. Anderson Cancer Center | 27 | 2015-02-20 | 2020-01-06 |
| Doxycycline in Treating Patients With Chronic Rhinosinusitis With Nasal Polyps Doxycycline, methylprednisolone, nasal saline spray - Polyp of Nasal Sinus | Phase 2 | Terminated | Icahn School of Medicine at Mount Sinai | 49 | 2014-09-01 | 2018-01-09 |
| Study of Promethazine for Treatment of Diabetic Gastroparesis Promethazine, Sugar pill - Diabetic Gastroparesis | Phase 2 | Terminated | Dartmouth-Hitchcock Medical Center | 3 | 2014-07-01 | 2018-08-07 |
| Glutamine for the Prevention of Radiation Toxicity in Subjects Conserving Therapy Glutamine, Placebo - Breast Cancer | Phase 2 | Terminated | University of Arkansas | 14 | 2014-06-01 | 2019-05-29 |
| Minocycline for Postsurgical Symptom Reduction in Head and Neck Cancer Minocycline, Placebo, Questionnaires - Head And Neck Cancer | Phase 2 | Terminated | M.D. Anderson Cancer Center | 30 | 2014-05-06 | 2022-10-20 |
| Naltrexone RCT for Treatment-Emergent Fatigue in Patients Receiving Radiation Therapy for Breast Cancer Naltrexone, Sugar Pill - Invasive Breast Cancer (Stage I-III), Ductal Carcinoma in Situ | Phase 2 | Terminated | Dana-Farber Cancer Institute | 3 | 2014-05-01 | 2021-11-16 |
| Asenapine for Bipolar Depression Asenapine, Placebo - Bipolar Depression | Phase 2 | Terminated | University of Cincinnati | 51 | 2013-09-01 | 2017-07-24 |
| Probiotic (VSL #3) for Gulf War Illness VSL#3, Placebo - Gulf War Illness | Phase 2 / Phase 3 | Terminated | University of Utah | 29 | 2013-09-01 | 2018-10-26 |
| Iloperidone for Symptoms of Arousal in Post Traumatic Stress Disorder (PTSD) Iloperidone, Placebo - Post Traumatic Stress Disorder | Phase 2 | Terminated | University of Colorado, Denver | 1 | 2013-07-01 | 2020-02-11 |
| Topiramate as an Adjunct to Amantadine in the Treatment of Dyskinesia in Parkinson's Disease Topiramate, Placebo, Amantadine - Idiopathic Parkinson's Disease, Drug Induced Dyskinesia | Phase 2 | Terminated | Rush University Medical Center | 42 | 2013-03-01 | 2019-04-16 |
| Mechanisms of Improved Wound Healing and Protein Synthesis of Insulin and Metformin Metformin, Sugar pill - Insulin Resistance, Hypermetabolism | Phase 2 / Phase 3 | Terminated | The University of Texas Medical Branch, Galveston | 36 | 2012-11-01 | 2019-11-29 |
Showing 20 of 36. Sign in to see all of them.
Alcoholism (3) · Breast Neoplasms (2) · Depression (2) · Adenocarcinoma of Lung (1) · Alcohol Drinking (1) · Alcohol-Related Disorders (1) · Alcoholic Intoxication (1) · Anemia, Sickle Cell (1) · Angina Pectoris (1) · Anxiety Disorders (1) · Atherosclerosis (1) · Attention Deficit Disorder with Hyperactivity (1) · Binge Drinking (1) · Bipolar Disorder (1) · Brain Injuries, Traumatic (1)
M.D. Anderson Cancer Center (3) · Corewell Health East (2) · Dana-Farber Cancer Institute (2) · University of Colorado, Denver (2) · Alicia Gerke (1) · Boston Medical Center (1) · Dartmouth-Hitchcock Medical Center (1) · Herlev Hospital (1) · Icahn School of Medicine at Mount Sinai (1) · Jennifer Cowger , MD, MS (1) · Johns Hopkins University (1) · National Center for Complementary and Integrative Health (NCCIH) (1) · National Heart, Lung, and Blood Institute (NHLBI) (1) · National Institute on Alcohol Abuse and Alcoholism (NIAAA) (1) · New York State Psychiatric Institute (1)
United States (32) · Canada (1) · Denmark (1) · United Kingdom (1)
Alicia K Gerke, MD (1) · Ann W Silk, MD, MS (1) · Anthony A Bavry, MD, MPH (1) · Azam Azargoon, MD (1) · Bankole Johnson, DSc,MD,PhD (1) · Benjamin D Malkin, MD (1) · Bernad Ravina, MD. MSCE (1) · Bertram Pitt, MD (1) · Brian E. Lacy, MD (1) · Caleb M Adler, MD (1) · Christopher G Goetz, MD (1) · Dariush Elahi, PhD (1) · David L. Ramirez, MD (1) · David N Herndon, MD (1) · Domenic A Ciraulo, MD (1)
PMID 19910321, PMID 21527519, PMID 21900080, PMID 22983573, PMID 23686372, PMID 24152824, PMID 24988120, PMID 25427171, PMID 31322833, PMID 31990759, PMID 32445052, PMID 34014839, PMID 34990411, PMID 37439373, PMID 39462179, PMID 42224366
P30MH071478 (1), P60AA013759 (1), R01AA010522 (1), R01AA015923 (1), R01CA026582 (1), R01CA150226 (1)