10 completed, 1 not yet recruiting, 1 terminated, 1 unknown. 14 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 14 | Completed 10, Not yet recruiting 1, Terminated 1, Unknown 1, Withdrawn 1 |
Follow Succinylcholine: new trials by email Literature Review of Succinylcholine trials Research Report on Succinylcholine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| REMIfentanil (2 vs. 4 mcg/kg) Facilitated Intubation Without Neuromuscular Blockade Versus Succinylcholine and Rocuronium With Sugammadex for Endotracheal Intubation in Spine Surgery Requiring Motor Evoked Potential Monitoring Low-Dose Remifentanil, High-Dose Remifentanil, Succinylcholine - Airway Management, Endotracheal Intubation | Phase 4 | Not yet recruiting | Mayo Clinic | 316 | 2026-09-01 | 2026-09-22 |
| Platform Adaptive Embedded Trial for Acute Respiratory Distress Syndrome protective ventilation, prone position ventilation, glucocorticoid therapy - Acute Respiratory Distress Syndrome | Phase 4 | Unknown | Second Affiliated Hospital, Zhejiang University, School of Medicine | 1000 | 2022-10-01 | 2022-12-21 |
| Intubating Conditions During Rapid Sequence Induction in Elderly With Either Suxamethonium 1.0 mg/kg or Rocuronium 1.0 mg/kg Suxamethonium, Rocuronium - Intubation Conditions | Phase 4 | Completed | Matias Vested | 102 | 2021-08-12 | 2024-03-19 |
| Effect of Neuromuscular Blockade on Pulmonary Complications in Elective Cardiac Surgery Succinylcholine, Cisatracurium - Neuromuscular Blockade, Postoperative Complications | Phase 4 | Completed | University of Chicago | 100 | 2016-03-01 | 2018-07-17 |
| Rocuronium + Sugammadex vs. Succinylcholine + Cisatracurium + Neostigmine/Atropine in Obese Participants (MK-8616-104) Rocuronium, Sugammadex, Cisatracurium - Neuromuscular Blockade | Phase 4 | Withdrawn | Merck Sharp & Dohme LLC | 2015-07-01 | 2015-07-13 | |
| Fade Upon TOF Stimulation Induced by Succinylcholine Succinylcholine - Muscle Relaxants | Phase 4 | Completed | University of Toledo Health Science Campus | 19 | 2015-04-01 | 2018-01-02 |
| High-Resolution Solid-State Manometry of the Effect of Succinylcholine on Barrier Pressure Succinylcholine - the Effect of Succinylcholine on Barrier Pressure | Phase 4 | Completed | China-Japan Friendship Hospital | 14 | 2015-03-01 | 2022-09-27 |
| Comparison of Surgical Conditions in Cesarean Section Under General Anesthesia With Deep Neuromuscular Blockade Versus Succinylcholine Rocuronium, Succinylcholine - Cesarean Section | Phase 4 | Completed | Charles University, Czech Republic | 91 | 2014-08-16 | 2019-02-11 |
| Mask Ventilation Before and After Neuromuscular Blockade Rocuronium, Vecuronium Bromide, Succinylcholine - Anesthesia | Phase 4 | Completed | University of Washington | 210 | 2014-08-01 | 2015-04-09 |
| Modern Myorelaxation Procedure and Reversal of Neuromuscular Blockade With General Anesthesia for Caesarean Section Rocuronium + sugammadex, Succinylcholine + Neostigmine - Caesarean Section, Pregnancy | Phase 4 | Completed | Brno University Hospital | 500 | 2012-09-01 | 2016-07-26 |
| Succinylcholine or Rocuronium for Rigid Bronchoscopy Under General Anesthesia succinylcholine, rocuronium - Anesthesia | Phase 4 | Terminated | Hopital Foch | 6 | 2012-01-01 | 2016-11-03 |
| Rapid Sequence Intubation With Rocuronium-Sugammadex Compared With Succinylcholine Rocuronium-Sugammadex, Succinylcholine - Rapid Sequence Intubation | Phase 4 | Completed | Copenhagen University Hospital, Rigshospitalet | 61 | 2009-09-01 | 2011-03-02 |
| Enhancing the Effectiveness of Electroconvulsive Therapy in Severe Depression ECT Mecta 5000M, Methohexitone, Suxamethonium - Depression | Phase 4 | Completed | St Patrick's Hospital, Ireland | 138 | 2008-05-01 | 2018-11-14 |
| Succinylcholine Versus Rocuronium for Emergency Intubation in Intensive Care Succinylcholine, Rocuronium - Intubation | Phase 4 | Completed | University Hospital, Basel, Switzerland | 420 | 2006-08-01 | 2011-12-15 |
Delayed Emergence from Anesthesia (1) · Depression (1) · Muscle Hypotonia (1) · Postoperative Complications (1) · Respiratory Distress Syndrome (1)
Brno University Hospital (1) · Charles University, Czech Republic (1) · China-Japan Friendship Hospital (1) · Copenhagen University Hospital, Rigshospitalet (1) · Hopital Foch (1) · Matias Vested (1) · Mayo Clinic (1) · Merck Sharp & Dohme LLC (1) · Second Affiliated Hospital, Zhejiang University, School of Medicine (1) · St Patrick's Hospital, Ireland (1) · University Hospital, Basel, Switzerland (1) · University of Chicago (1) · University of Toledo Health Science Campus (1) · University of Washington (1)
United States (4) · Czechia (2) · Denmark (2) · China (1) · France (1) · Ireland (1) · Switzerland (1)
Aaron M Joffe, DO (1) · Declan M McLoughlin, PhD (1) · Jan Blaha, MD, PhD (1) · Lars S Rasmussen (1) · Martin Siegemund, MD (1) · Morgan Le Guen, MD (1) · Rebecca M Gerlach, MD (1) · Shashi Bhatt, MD (1) · Shaun Gruenbaum, MD (1) · Stephan C Marsch, MD, DPhil (1) · Zhaocai Zhang, Doctor (1)