39 completed, 10 unknown, 8 terminated, 4 recruiting. 70 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 70 | Completed 39, Unknown 10, Terminated 8, Recruiting 4, Not yet recruiting 3, Suspended 2, Withdrawn 2, Active not recruiting 1, Enrolling by invitation 1 |
Follow Solutions: new trials by email Literature Review of Solutions trials Research Report on Solutions
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Investigate the Transition of Children From 'Artisanal" Cannabidiol (CBD) to Epidiolex Epidiolex 100 mg/mL Oral Solution - Dravet Syndrome (DS), Lennox-Gastaut Syndrome (LGS) | Phase 4 | Not yet recruiting | Elizabeth Donner | 25 | 2027-01-01 | 2026-09-11 |
| A Study of TAK-664 in People With Primary Immunodeficiency Diseases Who Have Not Yet Been Treated With Immunoglobulins TAK-664 - Primary Immunodeficiency Diseases (PID) | Phase 4 | Not yet recruiting | Takeda | 9 | 2026-11-01 | 2026-09-08 |
| Microneedling-Assisted Metformin, Tranexamic Acid, and Modified Kligman's Formula for Melasma Metformin 30% Topical Lotion, Tranexamic Acid 0.5% Topical Solution, Modified Kligman's Formula - Melasma (Facial Melasma) | Phase 4 | Enrolling by invitation | Sameh Sarsik | 80 | 2026-10-25 | 2026-10-27 |
| Sodium Bicarbonate for Critically Ill Patients With Metabolic Acidosis and Acute Kidney Injury Sodium Bicarbonate 8.4% Solution for Injection, Balanced crystalloid solution - Acute Kidney Injury, Metabolic Acidosis | Phase 4 | Recruiting | Universität Münster | 660 | 2026-05-07 | 2026-09-04 |
| Preventing Structural Damage in Early Psoriatic Arthritis Amgevita 40Mg Solution for Injection, Methotrexate (Metoject® prefilled pen) - Psoriatic Arthritis (PsA) | Phase 4 | Recruiting | Chinese University of Hong Kong | 108 | 2026-03-16 | 2026-03-23 |
| Preemptive IV Ibuprofen for Neurocognitive Recovery and Analgesic Needs After Inguinal Hernia Surgery Ibuprofen (400 mg x 4), Placebo (NaCl 0.9 % solution) - Inguinal Hernia Unilateral, Delayed Neurocognitive Recovery | Phase 4 | Completed | Mehmet Çiğdem | 76 | 2025-09-27 | 2026-03-03 |
| Comparing High Versus Low Dose of Oxytocin, in Gravida Women With BMI 30 and Above Which Are Undergoing Induction of Labor Oxytocin Grindeks 10 IU/ml- solution for injection - Induction of Labor, Augmentation of Labor | Phase 4 | Not yet recruiting | HaEmek Medical Center, Israel | 130 | 2025-06-01 | 2025-05-25 |
| Anti-viral Action Against Type 1 Diabetes Autoimmunity Comirnaty Injectable Product, Sodium Chloride 0.9% Inj - Diabetes Mellitus, Type 1 | Phase 4 | Recruiting | Technical University of Munich | 2252 | 2024-05-08 | 2025-09-23 |
| Approach to Ankle Sprains in the Emergency Department Dexketoprofen Trometamol 50 Mg/mL Solution for Injection, Ibuprofen 100 MG/ML Solution for Injection, Paracetamol 10 Mg/mL Solution for Injection - Ankle Sprains | Phase 4 | Completed | Ankara Etlik City Hospital | 150 | 2023-12-01 | 2024-08-20 |
| Comparison Between Pads With Cold Solution of Magnesium Sulfate or Cold Water Postpartum Perineal Pain and Healing Magnesium sulfate 33% solution, Cold water - Women After Delivery With Perineal Pain | Phase 4 | Completed | The Baruch Padeh Medical Center, Poriya | 131 | 2023-11-15 | 2026-09-09 |
| The Effect of Lixisenatide on the Effect of Pituitary Hormones Placebo, Lixisenatide 10 micrograms (50 micrograms/ml in 3 ml) Pen Injector - Healthy, Type 1 Diabetes | Phase 4 | Unknown | University of Tartu | 10 | 2023-04-17 | 2023-06-12 |
| Reducing Hypotensive Anesthesia Use With TXA During Orthognathic Surgery Avoidance of Deliberate Hypotensive Anesthesia, TRANEXAMIC ACID 1 G in 10 mL INTRAVENOUS INJECTION, SOLUTION - Hypotension During Surgery, Blood Loss, Surgical | Phase 4 | Completed | University of Alabama at Birmingham | 115 | 2022-11-11 | 2026-05-27 |
| Intravitreal Faricimab in Diabetic Macular Edema With Limited Response to Aflibercept FARICIMAB 6 Mg in 0.05 mL INTRAVITREAL INJECTION, SOLUTION [VABYSMO] - Diabetic Macular Edema | Phase 4 | Unknown | Vista Klinik | 30 | 2022-11-01 | 2022-11-09 |
| 7-Day Trial of Sucraid for Alleviating CSID Symptoms in Subjects With Low, Moderate, and Normal Sucrase Levels Sucraid (sacrosidase) Oral Solution 8500 IU/mL - Congenital Sucrase-Isomaltase Deficiency, CSID | Phase 4 | Terminated | QOL Medical, LLC | 312 | 2022-08-01 | 2025-03-20 |
| Clinical Trial for the Optimization of Indocyanine Green Administration in NIRF-C During L.Cholecystectomy. VERDYE powder for solution for injection 25 mg - Laparoscopic Cholecystectomy | Phase 4 | Completed | Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León | 200 | 2022-06-20 | 2025-06-17 |
| Intralesional Injection of Acyclovir Versus Candida Antigen in Treatment of Plantar Warts Acyclovir 250mg Powder for Solution for Infusion, each vial contains 250mg of acyclovir as the sodium salt, Chandra Bhagat Pharma Pvt. Ltd andcandida antigen - Acyclovir and Candida Antigen in Treatment of Plantar Wart | Phase 4 | Unknown | Sohag University | 40 | 2022-06-13 | 2022-06-23 |
| Melatonin for Pediatric Emergence Agitation Melatonin 5 MG/15 ML Oral Solution 0.05 mg/kg, Melatonin 5 MG/15 ML Oral Solution 0.2mg/kg, Melatonin 5 MG/15 ML Oral Solution 0.4mg/kg - Emergence Agitation | Phase 4 | Completed | Menoufia University | 117 | 2022-01-30 | 2023-10-12 |
| POCUS: Hemostatic Potential and Joint Health in Patients With Severe Hemophilia A on Novel Replacement Therapies Eloctate, Adynovate, Emicizumab - Hemophilia A, Factor VIII | Phase 4 | Withdrawn | University of Texas Southwestern Medical Center | 2021-04-15 | 2026-04-07 | |
| Effect Of Topical Prostaglandin F2α Analogs,Fractional CO2 Laser, Excimer Laser Or Their Combination In Treatment Of Vitiligo Topical travoprost 0.004% solution, Fractional CO2 laser, Excimer laser - Vitiligo, Excimer Laser | Phase 4 | Unknown | Assiut University | 30 | 2021-01-01 | 2020-10-22 |
| A Comparison of Ultrasound-guided Steroid Injection With Wrist Splint in Carpal Tunnel Syndrome Methylprednisolone Injection [Solu-Medrol], wrist splint - Carpal Tunnel Syndrome | Phase 4 | Unknown | Mercy Health Ohio | 70 | 2020-12-01 | 2021-09-09 |
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Obesity (7) · Diabetes Mellitus, Type 1 (2) · Hypotrichosis (2) · Infertility (2) · Migraine Disorders (2) · Onychomycosis (2) · Pain, Postoperative (2) · Acidosis (1) · Acute Coronary Syndrome (1) · Acute Kidney Injury (1) · Acute Pain (1) · Ankle Injuries (1) · Aortic Valve Disease (1) · Arthritis, Psoriatic (1) · Ascites (1)
University Medical Centre Ljubljana (6) · Assiut University (2) · Centro Ortopedico y Quirurgico del Pie (2) · Fresenius Kabi (2) · Hadassah Medical Organization (2) · University of Alabama at Birmingham (2) · Vista Klinik (2) · ATS Clinical Research (1) · Alcon Research (1) · Allergan (1) · Almirall, S.A. (1) · Ankara Etlik City Hospital (1) · Bayer (1) · Cairo University (1) · Centre Hospitalier le Mans (1)
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Andrej Janez, MD, PhD (2) · Eda Vrtacnik Bokal, professor (2) · Ahmet B. Erdem (1) · Alexander Zarbock, MD (1) · Andrej Janez, MD PhD (1) · Andres F Estupinan Bohorquez, MD (1) · Anette-G. Ziegler (1) · Ava Shamban, MD (1) · Boni E Elewski, MD (1) · Boris Mraovic, MD (1) · Brian Kinard, DMD, MD (1) · Diego F Viasus Perez, MD. PhD. (1)
PMID 15572968, PMID 20384750, PMID 20384751, PMID 22694845, PMID 22986417, PMID 24918475, PMID 24970272, PMID 25330463, PMID 25955349, PMID 26496361, PMID 27158544, PMID 29861076, PMID 30811142, PMID 31833000, PMID 32619039, PMID 34933701, PMID 35139802, PMID 35448942, PMID 35834645, PMID 36569131, PMID 36868593, PMID 40975121, PMID 42053118, PMID 42102324
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