9 completed, 7 active not recruiting, 4 unknown, 3 recruiting. 9 Not applicable, 6 Phase 2, 4 Phase 3, 2 Phase 1, 1 Phase 4.
Follow Sigmoidoscopy: new trials by email Literature Review of Sigmoidoscopy trials Research Report on Sigmoidoscopy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Testing the Effects of Exercise on Colorectal Cancer Development After Treatment With Pelvic Radiation Therapy for Prostate Cancer Aerobic Exercise, Biopsy Procedure, Biospecimen Collection - Colon Polyp, Colorectal Carcinoma | Not applicable | Recruiting | City of Hope Medical Center | 30 | 2026-12-16 | 2026-08-28 |
| Testing for Safety and Colorectal Cancer Preventive Effects of ONC201 Biopsy Procedure, Biospecimen Collection, Colonoscopy - Colorectal Adenomatous Polyp, Colorectal Carcinoma | Phase 1 | Recruiting | National Cancer Institute (NCI) | 36 | 2025-10-06 | 2026-10-15 |
| FOLFOX, Botensilimab, and Balstilimab for the Treatment of Localized Rectal Cancer Before Surgery Balstilimab, Biospecimen Collection, Botensilimab - Rectal Adenocarcinoma, Stage IIA Rectal Cancer AJCC v8 | Phase 2 | Recruiting | City of Hope Medical Center | 26 | 2025-05-20 | 2026-06-29 |
| Fecal Microbiota Transplantation for Patients With Chronic Widespread Pain Fecal Microbiota Transplantation, Sigmoidoscopy - Chronic Widespread Pain | Not applicable | Suspended | Chinese University of Hong Kong | 20 | 2025-01-01 | 2023-08-30 |
| Testing the Addition of an Anti-Cancer Drug, Irinotecan, to the Standard Chemotherapy Treatment (FOLFOX) After Long-Course Radiation Therapy for Advanced-Stage Rectal Cancers to Improve the Rate of Complete Response and Long-Term Rates of Organ Preservation and Continuing Response Capecitabine, 5-fluorouracil, Leucovorin calcium - Stage II Rectal Cancer AJCC v8, Stage III Rectal Cancer AJCC v8 | Phase 2 / Phase 3 | Active not recruiting | Alliance for Clinical Trials in Oncology | 760 | 2022-12-08 | 2026-09-25 |
| Therapy Adapted for High Risk and Low Risk HIV-Associated Anal Cancer Anoscopy, Biospecimen Collection, Capecitabine - AIDS-Related Anal Carcinoma, Anal Margin Squamous Cell Carcinoma | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 40 | 2022-08-09 | 2026-10-05 |
| Microbiome-Mediated Gut Dysfunction in Non-Alcoholic Fatty Liver Disease Sigmoidoscopy - Non-Alcoholic Fatty Liver Disease | Completed | AdventHealth Translational Research Institute | 38 | 2022-02-11 | 2026-04-03 | |
| Testing Nivolumab and Ipilimumab With Short-Course Radiation in Locally Advanced Rectal Cancer Computed Tomography, Ipilimumab, Magnetic Resonance Imaging - Locally Advanced Rectal Adenocarcinoma, Stage II Rectal Cancer AJCC v8 | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 31 | 2022-02-08 | 2026-10-22 |
| The Gut Immune System During Immune Checkpoint Inhibitor Therapy sigmoidoscopies and and venous blood sampling - Cancer | Active not recruiting | University Medical Center Groningen | 38 | 2021-10-30 | 2025-11-25 | |
| Nivolumab After Combined Modality Therapy in Treating Patients With High Risk Stage II-IIIB Anal Cancer Biopsy Procedure, Biospecimen Collection, Colonoscopy - Anal Basaloid Carcinoma, Anal Canal Cloacogenic Carcinoma | Phase 3 | Active not recruiting | National Cancer Institute (NCI) | 344 | 2018-07-05 | 2026-10-23 |
| Plant Exosomes +/- Curcumin to Abrogate Symptoms of Inflammatory Bowel Disease Sigmoidoscopy and biopsy, blood work - Irritable Bowel Disease | Not applicable | Completed | University of Louisville | 4 | 2018-03-01 | 2022-11-03 |
| Tailored Transition for IBD Adolescents Radiologic (MRE) or endoscopic (sigmoidoscopy) evaluation - Inflammatory Bowel Disease | Not applicable | Completed | Schneider Children's Medical Center, Israel | 70 | 2017-03-01 | 2022-10-27 |
| Abnormal Food Timing and Circadian Dyssynchrony in Alcohol Induced Colon Carcinogenesis Right time eating, Delayed time eating, Sigmoidoscopy - Colorectal Cancer | Not applicable | Active not recruiting | Rush University Medical Center | 12 | 2016-07-31 | 2026-09-16 |
| Mechanisms of Idelalisib-Associated Diarrhea in Patients With Relapsed Chronic Lymphocytic Leukemia, Indolent Non-hodgkin Lymphoma, or Small Lymphocytic Lymphoma Biospecimen Collection, Colonoscopy, Colposcopic Biopsy - Absence of Signs or Symptoms, B-Cell Non-Hodgkin Lymphoma | Terminated | Jonsson Comprehensive Cancer Center | 1 | 2016-02-01 | 2021-07-14 | |
| Analyzing IBS to Identify Biomarkers and Microbiome Signatures endoscopy for tissue biopsy, Blood Sample, Stool Sample - Diarrhoea Predominant Irritable Bowel Syndrome, IBS | Not applicable | Completed | Mayo Clinic | 26 | 2015-05-01 | 2017-07-07 |
| Cold Snare,Hot Snare and APC Polypectomy for the Complete Removal of Small Left Sided Colon Polyps polypectomy - Colonic Polyps | Completed | Evangelismos Hospital | 108 | 2015-01-01 | 2020-05-11 | |
| FMT in Ulcerative Colitis-Associated Pouchitis biologically active human fecal microbiota, sigmoidoscopy - Ulcerative Colitis Associated Pouchitis | Phase 2 | Completed | Virginia O. Shaffer | 8 | 2014-07-01 | 2019-03-27 |
| The Altitude Inflammatory Bowel Disease Study hypobaric pressure chamber, Sigmoidoscopy - Inflammatory Bowel Disease | Not applicable | Unknown | University of Zurich | 30 | 2014-05-01 | 2016-07-29 |
| Correlates and Consequences of Increased Immune Activation in Injection Drug Users Sigmoidoscopy with biopsy - Intravenous Drug Usage | Completed | Rockefeller University | 201 | 2012-12-01 | 2014-11-06 | |
| Efficacy Combined Fecal Immunochemical Test-Sigmoidoscopy for the Detection of Advanced Colorectal Neoplasia FIT-sigmoidoscopy, Colonoscopy - Colorectal Adenoma | Phase 4 | Unknown | Yonsei University | 5282 | 2012-08-01 | 2013-01-14 |
Showing 20 of 26. Sign in to see all of them.
Rectal Neoplasms (7) · Colorectal Neoplasms (5) · Adenomatous Polyposis Coli (2) · Anus Neoplasms (2) · Colitis, Ulcerative (2) · Colonic Neoplasms (2) · Colonic Polyps (2) · Inflammatory Bowel Diseases (2) · Anal Canal Carcinoma (1) · Chronic Pain (1) · Colitis, Collagenous (1) · Diarrhea (1) · Fatty Liver (1) · Fibrosis (1) · HIV Infections (1)
National Cancer Institute (NCI) (5) · City of Hope Medical Center (2) · AdventHealth Translational Research Institute (1) · Alliance for Clinical Trials in Oncology (1) · Barbara Ann Karmanos Cancer Institute (1) · Bonderup, Ole K., M.D. (1) · Chinese University of Hong Kong (1) · Cosmo Technologies Ltd (1) · Evangelismos Hospital (1) · Jonsson Comprehensive Cancer Center (1) · Mayo Clinic (1) · Rockefeller University (1) · Rush University Medical Center (1) · Schneider Children's Medical Center, Israel (1) · Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University (1)
United States (16) · Puerto Rico (2) · Canada (1) · Denmark (1) · Greece (1) · Hong Kong (1) · Israel (1) · Netherlands (1) · South Korea (1)
Alexander G Raufi, MD (1) · Ali Keshavarzian, MD (1) · Amy Foxx-Orenstein, DO (1) · Antonio Gasbarrini, Prof (1) · Bhaumik B. Patel, MD (1) · Christine D Berg (1) · Daniel Hommes (1) · Dong Il Park, M.D., ph D. (1) · Eun Soo Kim, M.D. (1) · Gregory Idos (1) · Hong Jun Park, M.D. (1) · Hwang Choi, M.D., ph D. (1) · Hyun Gun Kim, M.D. (1) · Hyun-Soo Kim, M.D., ph D. (1) · J. Joshua Smith, MD (1)
PMID 11096167, PMID 11529208, PMID 12733140, PMID 15700317, PMID 18838718, PMID 19035980, PMID 19426835, PMID 22612596, PMID 26269366, PMID 26559156, PMID 27521361, PMID 28057654, PMID 29802852, PMID 33277073, PMID 34548240, PMID 35048657, PMID 37647138, PMID 38712176, PMID 38741776, PMID 39060961, PMID 39116386, PMID 41261199, PMID 41400272, PMID 42328901
P30CA033572 (2), U10CA180820 (2), P30CA046592 (1), U10CA180821 (1), UG1CA242632 (1), UM1CA121947 (1)