4 completed, 3 withdrawn, 2 unknown, 1 not yet recruiting. 12 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 12 | Completed 4, Withdrawn 3, Unknown 2, Not yet recruiting 1, Recruiting 1, Terminated 1 |
| Phase 1 | 1 | Completed 1 |
Follow Sham rTMS: new trials by email Literature Review of Sham rTMS trials Research Report on Sham rTMS
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Pharmacological Stress and rTMS on Executive Function in Opioid Use Disorder Yohimbine + Hydrocortisone, Active rTMS, Placebo - Opioid Use Disorder | Phase 2 | Not yet recruiting | Wayne State University | 20 | 2026-10-01 | 2025-12-30 |
| Neuroimaging Correlates and Feasibility of Transcranial Magnetic Stimulation (TMS) to Improve Smoking Cessation Outcomes in Veterans With Comorbid PTSD active repetitive transcranial magnetic stimulation, sham repetitive transcranial magnetic stimulation, cognitive behavioral therapy for smoking cessation - Tobacco Use Disorder | Phase 2 | Recruiting | VA Office of Research and Development | 50 | 2023-10-31 | 2026-02-18 |
| Using rTMS to Explore Neural Mechanisms of Stress-Induced Opioid Use Placebo oral tablet, Yohimbine + Hydrocortisone, sham rTMS - Stress, Opioid-use Disorder | Phase 2 | Withdrawn | Wayne State University | 2023-04-10 | 2023-04-13 | |
| rTMS of Limbic Circuitry in Stress Modulation in Healthy Volunteers yohimbine + hydrocortisone, medial prefrontal cortex rTMS, Placebo oral tablet - Stress, Healthy | Phase 2 | Withdrawn | Wayne State University | 2023-04-10 | 2023-04-13 | |
| iTBS-DCS in Obsessive Compulsive Disorder iTBS repetitive Transcranial Magnetic Stimulation (rTMS), Sham rTMS, D-cycloserine - Obsessive-Compulsive Disorder | Phase 2 | Unknown | University of Calgary | 81 | 2021-11-26 | 2023-09-13 |
| TMS in Inflammatory Bowel Disease iTBS repetitive Transcranial Magnetic Stimulation (rTMS), Sham rTMS - Inflammatory Bowel Diseases, Maladaptive Behavior Associated With Physical Illness | Phase 2 | Terminated | University of Calgary | 12 | 2021-11-01 | 2023-04-18 |
| Combining rTMS With Varenicline to Prevent Smoking Lapse in Schizophrenia Active rTMS (20Hz), Sham rTMS - Tobacco Use Disorder, Schizophrenia | Phase 2 | Withdrawn | Centre for Addiction and Mental Health | 2018-07-01 | 2023-09-06 | |
| A Preliminary Investigation of Pre-Frontal Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Cannabis Use Disorder Active rTMS, Sham rTMS - Cannabis Use Disorder | Phase 2 | Completed | Stanford University | 72 | 2017-08-01 | 2023-08-09 |
| rTMS Effects in the Neuromodulation and Pain Threshold of Chronic Myofascial Pain Patients rTMS, Sham rTMS - Chronic Pain | Phase 2 | Unknown | Hospital de Clinicas de Porto Alegre | 24 | 2013-08-01 | 2013-10-21 |
| 50 Hz Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Parkinson's Disease 50 HZ Repetitive TMS, Sham rTMS - Parkinson Disease | Phase 1 / Phase 2 | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 26 | 2009-09-01 | 2012-12-27 |
| Transcranial Magnetic Stimulation for Treating Women With Chronic Widespread Pain rTMS, Sham rTMS - Fibromyalgia, Chronic Pain | Phase 2 | Completed | University of Washington | 19 | 2008-02-01 | 2013-05-23 |
| A Clinical Trial of Magnetic Stimulation in Depression Repetitive transcranial magnetic stimulation (rTMS), Sham rTMS, Repetitive Transcranial Magnetic Stimulator - Depression | Phase 2 | Completed | US Department of Veterans Affairs | 48 | 2001-10-01 | 2013-04-01 |
Chronic Pain (2) · Depression (2) · Opioid-Related Disorders (2) · Tobacco Use Disorder (2) · Depressive Disorder, Major (1) · Fatigue (1) · Fatigue Syndrome, Chronic (1) · Fibromyalgia (1) · Inflammatory Bowel Diseases (1) · Obsessive-Compulsive Disorder (1) · Pain (1) · Parkinson Disease (1) · Schizophrenia (1) · Smoking (1) · Tobacco Use Cessation (1)
Wayne State University (3) · University of Calgary (2) · Centre for Addiction and Mental Health (1) · Hospital de Clinicas de Porto Alegre (1) · National Institute of Neurological Disorders and Stroke (NINDS) (1) · Stanford University (1) · US Department of Veterans Affairs (1) · University of Washington (1) · VA Office of Research and Development (1)
United States (6) · Canada (2) · Brazil (1)
Alexander McGirr, MD, PhD (1) · David H. Avery, MD (1) · Gregory Sahlem, MD (1) · Jonathan R Young, MD (1) · Mark Greenwald, PhD (1) · Mark K Greenwald, PhD (1) · Stephen E. Nadeau, MD BS BS (1) · Wolnei Caumo, PhD (1)
PMID 20643486, PMID 22464727, PMID 24769437, PMID 24968008, PMID 29486960
K23DA043628 (1), R21AR053963 (1)