14 completed, 5 unknown, 1 active not recruiting, 1 recruiting. 9 Not applicable, 8 Phase 4, 5 Phase 2, 2 Phase 3, 1 Phase 1.
Follow Regular Insulin: new trials by email Literature Review of Regular Insulin trials Research Report on Regular Insulin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Feasibility of Intranasal Insulin in Patients With Spinal Cord Injury Regular Insulin, 0.9 % Normal Saline - Spinal Cord Injury | Phase 1 | Recruiting | HealthPartners Institute | 12 | 2026-02-20 | 2026-09-15 |
| The Effect of Intranasal Insulin Administration on Cognitive Function After Cardiac Surgery. Regular insulin, Normal Saline Flush, 0.9% Injectable Solution - Cognitive Decline, Heart Diseases | Not applicable | Unknown | McGill University Health Centre/Research Institute of the McGill University Health Centre | 316 | 2022-04-01 | 2021-01-26 |
| Glycemic Control After Antenatal Corticosteroids in Women With Pregestational and Gestational Diabetes Sliding Scale Insulin, Up-Titration of Home Insulin, Continuous Insulin Infusion - Diabetes Mellitus, Type 2, Preterm Birth | Phase 2 | Active not recruiting | University of Alabama at Birmingham | 120 | 2022-02-10 | 2026-07-14 |
| Effect of Insulin on Wound Healing-A Randomized Controlled Trial Insulin - Wound Heal | Phase 4 | Unknown | Ministry of Health, Bahrain | 30 | 2020-08-01 | 2020-05-19 |
| Phase 2, Randomized, Open-Label, Crossover, PD/PK Study of a Novel Pram-Insulin Co-Formulation in Adults With T1D PRAM9, Regular Insulin + Pramlintide, Regular Insulin - Diabetes Mellitus, Type 1, Insulin-dependent Diabetes Mellitus | Phase 2 | Completed | Xeris Pharmaceuticals | 18 | 2019-08-22 | 2024-03-27 |
| Insulin Glargine Versus Regular Insulin Based Regimens in Glycemic Control After Acute Stroke Insulin Glargine, Regular Insulin - Acute Stroke, Hyperglycemia | Phase 3 | Unknown | National Taiwan University Hospital | 120 | 2015-12-01 | 2016-08-19 |
| Insulin in Treatment of Diabetes Mellitus With Pregnancy Basal insulin analogue, rapid acting insulin, Neutral Protamine Hagedorn - Diabetes | Not applicable | Completed | Assiut University | 110 | 2015-01-01 | 2021-01-27 |
| Safety and Efficacy Study of Correcting Hyperglycemia in Patients With Diabetes Having Out-patient Surgery Regular Insulin, Humalog - Type 1 Diabetes, Type 2 Diabetes | Phase 4 | Withdrawn | Emory University | 2013-10-01 | 2017-03-15 | |
| Glargine Insulin vs.Continuous Regular Insulin in Diabetic Surgical Patients Receiving Parenteral Nutrition (GLUCOSE-in-PN) Glargine Insulin, Regular insulin - Diabetic Patients With Gastrointestinal Cancer Undergoing Surgery and Receiving Parenteral Nutrition | Phase 4 | Completed | King Faisal Specialist Hospital & Research Center | 61 | 2013-03-01 | 2016-02-25 |
| Effectiveness of Subcutaneous Glargine On The Time To Closure of The Anion Gap in Patients Presenting to the Emergency Department With Diabetic Keto-acidosis Insulin Glargine, Regular Insulin - Diabetic Ketoacidosis | Not applicable | Completed | The University of Texas Health Science Center, Houston | 40 | 2012-11-01 | 2017-05-16 |
| Feasible Insulin Algorithm for Glycemic Control in Patients With Acute Coronary Syndrome Regular Insulin - Acute Coronary Syndrome | Phase 4 | Suspended | Universidade Positivo | 130 | 2012-08-01 | 2012-06-19 |
| Physiologic Response to Glucagon at Varying Insulin Levels Glucagon, Insulin - Type 1 Diabetes Mellitus | Not applicable | Completed | Legacy Health System | 11 | 2011-11-01 | 2016-03-29 |
| Pegvisomant With Glucagon Test to Assess for Adult Growth Hormone Deficiency Pegvisomant, Regular insulin - Adults Growth Hormone Deficiency. | Not applicable | Unknown | Oregon Health and Science University | 10 | 2011-03-01 | 2013-10-24 |
| Various Insulin Regimens for Diabetic Inpatients With Cirrhosis Trial Glargine & Glulisine, Regular insulin, NPH & regular insulin - Type 2 Diabetes, Liver Cirrhosis | Phase 4 | Unknown | Cairo University | 45 | 2011-01-01 | 2010-06-15 |
| Evaluation of the Safety and Efficacy of Insulin Glargine + Glulisine or Insulin Regular + NPH Insulin (Isophane Insulin) Use in Type 2 Diabetes Mellitus Patients With Moderate Renal Failure. INSULIN GLARGINE, NPH insulin (insulin isophane), INSULIN GLULISINE - Diabetes Mellitus, Type 2 | Phase 4 | Completed | Sanofi | 72 | 2010-07-01 | 2013-11-08 |
| Comparison on Efficacy and Safety of Three Inpatient Insulin Therapy in Type2 DM regular insulin, 70/30 insulin, Glargine - Diabetes Mellitus (DM) | Not applicable | Completed | Cairo University | 63 | 2010-03-01 | 2019-01-15 |
| Effectiveness of Metformin Compared to Insulin in Pregnant Women With Mild Preexisting or Early Gestational Diabetes Metformin, Insulin - Non Insulin Dependent Diabetes, Pregnancy | Phase 2 | Completed | University of North Carolina, Chapel Hill | 31 | 2008-08-01 | 2017-04-25 |
| Glutathione Metabolism in Adolescents With Type 1 Diabetes - Study B Antioxidant supplement, Diabetes treatment, Regular Insulin - Diabetes Mellitus, Type 1 | Not applicable | Completed | Nemours Children's Clinic | 41 | 2008-03-01 | 2023-05-17 |
| Basal Bolus Insulin Versus SSRI in Type 2 Diabetes Undergoing General Surgery Insulin glargine, Regular insulin, Insulin glulisine - Type 2 Diabetes, Inpatient Hyperglycemia | Phase 4 | Completed | Emory University | 234 | 2007-12-01 | 2014-03-12 |
| Glutathione Metabolism in Adolescents With Type 1 Diabetes - Study A Cysteine isotope infusion at normoglycemia vs hyperglycemia, Regular Insulin - Diabetes Mellitus, Type 1 | Not applicable | Completed | Nemours Children's Clinic | 10 | 2007-06-01 | 2023-07-10 |
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Diabetes Mellitus (8) · Insulin Resistance (7) · Diabetes Mellitus, Type 2 (6) · Diabetes Mellitus, Type 1 (5) · Hyperglycemia (3) · Cognitive Dysfunction (2) · Fibrosis (2) · Acidosis (1) · Acute Coronary Syndrome (1) · Alzheimer Disease (1) · Amyloidosis (1) · Burns (1) · Cognition Disorders (1) · Delirium (1) · Diabetes, Gestational (1)
Cairo University (2) · Emory University (2) · Nemours Children's Clinic (2) · Assiut University (1) · HealthPartners Institute (1) · King Faisal Specialist Hospital & Research Center (1) · Legacy Health System (1) · McGill University Health Centre/Research Institute of the McGill University Health Centre (1) · Ministry of Health, Bahrain (1) · National Taiwan University Hospital (1) · Oregon Health and Science University (1) · Sanofi (1) · The University of Texas Health Science Center, Houston (1) · The University of Texas Medical Branch, Galveston (1) · Universidade Positivo (1)
United States (15) · Brazil (2) · Egypt (2) · Italy (1) · Saudi Arabia (1) · Taiwan (1)
Dominique Darmaun, MD, PhD (2) · Ahmad A Khairy, MD (1) · Andrea Valasquez (1) · Ashley Hickman, MD (1) · Ashley N Battarbee, MD (1) · Carlson Karen, MD (1) · David N. Herndon, MD (1) · George Atiee (1) · George Selby, MD (1) · Guilhermo E Umpierrez, MD (1) · Guillermo Umpierrez, MD (1) · Hakeam A Hakeam, MS., BCPS (1) · Ibtisam Z Eissa, MD (1) · Jiann-Shing Jeng, MD. PhD (1)
PMID 17327353, PMID 18791359, PMID 19240154, PMID 19366972, PMID 20395554, PMID 20701787, PMID 20739853, PMID 21228246, PMID 21789167, PMID 21911655, PMID 22606232, PMID 23096052, PMID 23511841, PMID 26013711, PMID 26496767, PMID 34075142, PMID 35667792, PMID 36656551, PMID 37515943
K23HD103875 (1), P50GM060338 (1), R01AG027415 (1), R01GM056687 (1)