15 completed, 9 unknown, 7 recruiting, 4 terminated. 39 Phase 2, 11 Phase 3, 10 Phase 1.
Follow PRP: new trials by email Literature Review of PRP trials Research Report on PRP
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Regenerative Medicine for Joint Hypermobility and Instability Dextrose 20% Prolotherapy, Autologous Platelet-Rich Plasma, Doxycycline Hyclate Injectable (Investigational) - Ehlers-Danlos Syndrome Hypermobility Type (hEDS), Ehlers-Danlos Syndrome (EDS) | Phase 1 / Phase 2 | Not yet recruiting | Manhattan Pain Medicine, PLLC | 100 | 2027-01-15 | 2026-10-06 |
| Evaluating Mechanically Engineered Stem Cell Exosomes for Treating Endometrial Injury: A Clinical Study Mechanically Engineered Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes, Umbilical cord mesenchymal stem cell-derived exosomes, platelet-rich plasma - Thin Endometrial Lining, Female Infertility | Phase 1 / Phase 2 | Recruiting | Tang-Du Hospital | 90 | 2025-02-21 | 2025-03-26 |
| Subtenon Autologous Platelet-Rich Plasma in Inherited and Degenerative Retinal Diseases Subtenon Injection of Autologous Platelet-Rich Plasma - Extensive Macular Atrophy With Pseudodrusen (EMAP), Retinitis Pigmentosa (RP) | Phase 1 / Phase 2 | Active not recruiting | Rubens Camargo Siqueira | 30 | 2025-01-04 | 2026-07-01 |
| Orthobiologic Treatment for Knee Osteoarthritis PRP injection, ADSTEM Inj. (Adult human mesenchymal stem cells), Injection - Osteoarthritis Knee | Phase 2 / Phase 3 | Enrolling by invitation | University Hospital of North Norway | 160 | 2024-09-23 | 2026-06-15 |
| Treatment of Patellofemoral Osteoarthritis With Engineered Cartilage. N-TEC, Platelet rich plasma - Patellofemoral Osteoarthritis | Phase 2 | Recruiting | University Hospital, Basel, Switzerland | 75 | 2024-06-06 | 2026-09-10 |
| Scheduled Autologous PRP Guided Injection in the Maxillary Bony Defects Autologous platelet-rich plasma - Bony Defect | Phase 2 | Completed | Horus University | 16 | 2023-08-15 | 2025-08-07 |
| Safety and Preliminary Efficacy of iEVs Injection in Treating Lateral Epicondylitis of Humerus iEV, PRP, immobilization - Lateral Epicondylitis | Phase 1 / Phase 2 | Recruiting | Shanghai 6th People's Hospital | 24 | 2023-07-01 | 2025-08-08 |
| Biological Response to Platelet-rich Plasma and Corticosteroid Injections Triamcinolone Acetonide 40 mg/ml Inj, Susp, Platelet-rich plasma Inj - Knee Osteoarthritis | Phase 1 / Phase 2 | Terminated | University of Missouri-Columbia | 23 | 2022-12-28 | 2025-06-25 |
| Effectiveness of PRP, Conditioned Medium UC-MSCs Secretome and Hyaluronic Acid for the Treatment of Knee Osteoarthritis Platelet-rich Plasma, Conditioned Medium From Umbilical Cord Mesenchymal Stem Cell Culture (MSCs) Secretome, Low Molecular Weight Hyaluronic Acid - Knee Osteoarthritis | Phase 1 / Phase 2 | Completed | Universitas Sriwijaya | 45 | 2022-10-02 | 2026-05-22 |
| Effectiveness of iPRF Injections in Temporomandibular Joints Degeneration Management Injectable platelet-rich fibrin, Platelet-rich plasma - Temporomandibular Disorder, Temporomandibular Joint Disorders | Phase 2 / Phase 3 | Enrolling by invitation | Wroclaw Medical University | 42 | 2022-01-24 | 2026-07-10 |
| PRP Versus Saline in Lateral Epicondylitis Platelet rich plasma injection, Saline injection - Lateral Epicondylitis, Unspecified Elbow | Phase 2 / Phase 3 | Unknown | Singapore General Hospital | 70 | 2021-11-01 | 2021-11-18 |
| Efficacy of Ultrasound-Guided PRP Versus Corticosteroid Injection in Patients With Ulnar Neuropathy at Elbow Triamcinolone Acetonide 40mg/mL, PRP - Ulnar Neuropathy at Elbow | Phase 2 / Phase 3 | Completed | Tanta University | 60 | 2021-06-01 | 2022-10-05 |
| PRP for Treatment of Peyronie's Disease Autologous Platelet-Rich Plasma (PRP), Placebo (Normal Saline) - Peyronie Disease, Sexual Dysfunction, Physiological | Phase 2 | Completed | University of Miami | 65 | 2021-03-29 | 2026-08-03 |
| A RCT on the Effect of Platelets Rich Plasma in ICSI Patients With Recurrent Implantation Failure PRP - Pregnancy Outcome | Phase 2 | Unknown | Dr. Osman Hospital | 86 | 2020-06-15 | 2020-06-17 |
| Outcome of Platelet Rich Plasma in ICSI Patients, a Randomized Controlled Trial PRP - Pregnancy Outcome | Phase 2 | Unknown | Dr. Osman Hospital | 788 | 2020-06-15 | 2020-06-17 |
| Safety and Efficacy of Autologous Platelet-Rich Plasma for Erectile Dysfunction. Autologous Platelet Rich Plasma, Saline solution - Erectile Dysfunction | Phase 2 | Completed | University of Miami | 61 | 2020-05-21 | 2024-01-09 |
| Clinical Trial to Evaluate the Efficacy of Intracavernosal Infusion of PRP vs PPP for the Erectile Dysfunction. PRP, PPP - Erectile Dysfunction | Phase 2 | Unknown | Puerta de Hierro University Hospital | 52 | 2020-02-10 | 2020-08-06 |
| Autologous PRP Infusion May Restore Ovarian Function and May Promote Folliculogenesis in POI Patients Autologous Platelet Rich Plasma, Placebo-Platelet Free Plasma - Menopause, Premature, Menopause Related Conditions | Phase 2 / Phase 3 | Recruiting | Genesis Athens Clinic | 100 | 2019-07-30 | 2026-07-08 |
| Autologous Platelet-rich Plasma to Improve Responsiveness and Embryo Quality in Patients With Poor Ovarian Response PRP - Infertility | Phase 2 | Unknown | Nanjing University | 50 | 2019-07-20 | 2021-11-03 |
| Autologous Platelet Rich Plasma (PRP) Intra Ovarian Infusion in Perimenopausal Women Autologous Platelet Rich Plasma (PRP) intra ovarian infusion, Placebo: Autologous Platelet Free Plasma (PFP) intra ovarian infusion - Infertility, Female, Perimenopausal Disorder | Phase 2 / Phase 3 | Recruiting | Genesis Athens Clinic | 100 | 2019-06-13 | 2026-07-08 |
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Osteoarthritis, Knee (6) · Infertility, Female (4) · Infertility (3) · Osteoarthritis (3) · Congenital Abnormalities (2) · Erectile Dysfunction (2) · Gynatresia (2) · Tennis Elbow (2) · Anetoderma (1) · Cicatrix (1) · Diabetes, Gestational (1) · Diabetic Retinopathy (1) · Ehlers-Danlos Syndrome (1) · Ehlers-Danlos syndrome type 3 (1) · Genital Diseases, Male (1)
Genesis Athens Clinic (4) · Dr. Osman Hospital (2) · University of Miami (2) · Aditya K Aggarwal (1) · Ain Shams University (1) · Cairo University (1) · David M. Brown, M.D. (1) · Dr Cipto Mangunkusumo General Hospital (1) · Dr. Himanshu Bansal Foundation (1) · Egyptian Atomic Energy Authority (1) · Horus University (1) · Jaeb Center for Health Research (1) · Manhattan Pain Medicine, PLLC (1) · Minia University (1) · Nanjing University (1)
United States (8) · Egypt (5) · Greece (4) · China (3) · Brazil (2) · Germany (2) · Indonesia (2) · Spain (2) · Canada (1) · Croatia (1) · Finland (1) · India (1) · Italy (1) · Norway (1) · Poland (1)
Hisham Gouda, MD (2) · Aditya K Aggarwal, MS,DNB,DO (1) · Agni Pantou, M.D (1) · Agni Pantou, MD (1) · Andrew Antoszyk, MD (1) · David M Brown, MD (1) · Eman Abdel Salam, Prof (1) · Fernandi Moegni, MD,OBGYN(C) (1) · Haixiang Sun, PhD (1) · Heather G. Huddleston, MD (1) · Hinrich Staecker, MD (1) · Jason Siefferman, MD (1) · Javier Gonzalez Iglesias, Dr (1) · Juan Martinez-Salamanca, Md, PhD (1) · Kenneth Lee, MD (1)
PMID 15039276, PMID 18587624, PMID 21902602, PMID 22738319, PMID 23559821, PMID 23885648, PMID 25035839, PMID 25925602, PMID 26861957, PMID 28146403, PMID 28287489, PMID 31901394, PMID 32181337, PMID 32551947, PMID 33320223, PMID 33956075, PMID 34505846, PMID 34560869, PMID 34711824, PMID 34945097, PMID 36089055, PMID 36100520, PMID 36369425, PMID 37972038, PMID 38588501, PMID 39643206, PMID 40840982, PMID 42193355
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